Discovery, synthesis, biological evaluation and molecular docking study of (R)-5-methylmellein and its analogs as selective monoamine oxidase A inhibitors.

[1]  L. Legoabe,et al.  Synthesis and evaluation of 2-substituted 4(3H)-quinazolinone thioether derivatives as monoamine oxidase inhibitors. , 2018, Bioorganic & medicinal chemistry.

[2]  Shiyang Zhou,et al.  Design, synthesis and biological evaluation of lazabemide derivatives as inhibitors of monoamine oxidase. , 2018, Bioorganic & medicinal chemistry.

[3]  Aliya Ibrar,et al.  Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery. , 2018, Bioorganic & medicinal chemistry.

[4]  E. Uriarte,et al.  Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis. , 2018, Journal of medicinal chemistry.

[5]  Yan Li,et al.  Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease. , 2018, Bioorganic & medicinal chemistry.

[6]  A. Tripathi,et al.  Privileged scaffolds as MAO inhibitors: Retrospect and prospects. , 2018, European journal of medicinal chemistry.

[7]  F. A. Saddique,et al.  Synthesis, monoamine oxidase inhibition activity and molecular docking studies of novel 4-hydroxy-N'-[benzylidene or 1-phenylethylidene]-2-H/methyl/benzyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides. , 2018, European journal of medicinal chemistry.

[8]  Ki Duk Park,et al.  Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy. , 2018, Bioorganic & medicinal chemistry.

[9]  J. P. Petzer,et al.  The evaluation of 1,4-benzoquinones as inhibitors of human monoamine oxidase. , 2017, European journal of medicinal chemistry.

[10]  Wenmin Liu,et al.  Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease. , 2017, Bioorganic & medicinal chemistry.

[11]  Wei Li,et al.  Ruthenium-NHC-Diamine Catalyzed Enantioselective Hydrogenation of Isocoumarins. , 2017, Journal of the American Chemical Society.

[12]  Xiaobing Wang,et al.  Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease. , 2016, Bioorganic & medicinal chemistry.

[13]  Khaled M. Elokely,et al.  Isolation of Acacetin from Calea urticifolia with Inhibitory Properties against Human Monoamine Oxidase-A and -B. , 2016, Journal of natural products.

[14]  E. Uriarte,et al.  Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors. , 2016, Journal of medicinal chemistry.

[15]  Liangdong Guo,et al.  A new sesquiterpene from the entomogenous fungus Phomopsis amygdali , 2016, Natural product research.

[16]  Wei Wang,et al.  Chemical Constituents from the Fermented Mycelia of the Medicinal Fungus Xylaria nigripes , 2016 .

[17]  Zhengtao Wang,et al.  Inhibitive activities detection of monoamine oxidases (MAO) A and B inhibitors in human liver MAO incubations by UPLC-ESI-MS/MS. , 2015, Journal of pharmaceutical and biomedical analysis.

[18]  Dong Jin Kim,et al.  Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors. , 2015, Bioorganic & medicinal chemistry.

[19]  J. Xiong,et al.  Xylapyrrosides A and B, two rare sugar-morpholine spiroketal pyrrole-derived alkaloids from Xylaria nigripes: isolation, complete structure elucidation, and total syntheses , 2015 .

[20]  I. Chen,et al.  Chemical Constituents of the Endophytic Fungus Hypoxylon sp. 12F0687 Isolated from Taiwanese Ilex formosana , 2015 .

[21]  Xingshu Li,et al.  Synthesis and evaluation of selegiline derivatives as monoamine oxidase inhibitor, antioxidant and metal chelator against Alzheimer's disease. , 2015, Bioorganic & medicinal chemistry.

[22]  J. N. Low,et al.  Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry. , 2015, Chemical communications.

[23]  J. Finberg Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: focus on modulation of CNS monoamine neurotransmitter release. , 2014, Pharmacology & therapeutics.

[24]  P. Ghosh,et al.  FeCl3 mediated one-pot route to nitriles , 2013 .

[25]  Ki Duk Park,et al.  Oxazolopyridines and thiazolopyridines as monoamine oxidase B inhibitors for the treatment of Parkinson's disease. , 2013, Bioorganic & medicinal chemistry.

[26]  O. Nicolotti,et al.  Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors. , 2013, Journal of medicinal chemistry.

[27]  J. Sakayaroj,et al.  Indanone and mellein derivatives from the Garcinia-derived fungus Xylaria sp. PSU-G12 , 2013 .

[28]  G. Herzner,et al.  Larvae of the parasitoid wasp Ampulex compressa sanitize their host, the American cockroach, with a blend of antimicrobials , 2013, Proceedings of the National Academy of Sciences.

[29]  J. Terao,et al.  Evaluation of the inhibitory effects of quercetin-related flavonoids and tea catechins on the monoamine oxidase-A reaction in mouse brain mitochondria. , 2012, Journal of agricultural and food chemistry.

[30]  L. Santana,et al.  Focusing on new monoamine oxidase inhibitors: differently substituted coumarins as an interesting scaffold. , 2012, Current topics in medicinal chemistry.

[31]  D. Flockhart Dietary restrictions and drug interactions with monoamine oxidase inhibitors: an update. , 2012, The Journal of clinical psychiatry.

[32]  L. Ng,et al.  Immunomodulatory properties of Xylaria nigripes in peritoneal macrophage cells of Balb/c mice. , 2011, Journal of ethnopharmacology.

[33]  E. Uriarte,et al.  Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors. , 2011, Journal of medicinal chemistry.

[34]  J. Wouters,et al.  Synthesis and evaluation of β-carboline derivatives as potential monoamine oxidase inhibitors. , 2011, Bioorganic & medicinal chemistry.

[35]  Ying Yang,et al.  Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors. , 2010, Bioorganic & medicinal chemistry.

[36]  J. Shih,et al.  Monoamine oxidase inactivation: from pathophysiology to therapeutics. , 2008, Advanced drug delivery reviews.

[37]  F. Sugawara,et al.  Synthesis and Absolute Configuration of (+)‐Pseudodeflectusin: Structural Revision of Aspergione B , 2006 .

[38]  M. Helliwell,et al.  Addition of lithiated tertiary aromatic amides to epoxides and;aziridines: Asymmetric synthesis of (S)-(+)-mellein , 2006 .

[39]  Keith F. Tipton,et al.  The therapeutic potential of monoamine oxidase inhibitors , 2006, Nature Reviews Neuroscience.

[40]  Z. Yao,et al.  Synthesis studies toward chloroazaphilone and vinylogous gamma-pyridones: two common natural product core structures. , 2005, The Journal of organic chemistry.

[41]  U. Bonnet Moclobemide: therapeutic use and clinical studies. , 2003, CNS drug reviews.

[42]  A. Kalgutkar,et al.  Interactions of nitrogen-containing xenobiotics with monoamine oxidase (MAO) isozymes A and B: SAR studies on MAO substrates and inhibitors. , 2001, Chemical research in toxicology.

[43]  I. Yoo,et al.  5-methylmellein and nectriapyrone, two new monoamine oxidase inhibitors , 1999 .

[44]  J. Shih,et al.  Determination of regions important for monoamine oxidase (MAO) A and B substrate and inhibitor selectivities. , 1998, Journal of neural transmission. Supplementum.

[45]  Robert A. Copeland,et al.  Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis , 1996 .

[46]  R. Silverman Radical Ideas about Monoamine Oxidase , 1995 .