Moyamoya disease associated with pituitary adenoma--report of two cases.

Moyamoya disease associated with prolactin (PRL)-producing pituitary adenomas occurred in two females with elevated blood PRL levels (285 and 120 ng/ml). Computed tomography revealed cystic tumors extending from the sella turcica to the suprasellar cistern. Carotid angiography demonstrated stenoses or obstructions of the bilateral internal carotid arteries at their end point and development of bilateral basal moyamoya vessels. Histological diagnosis in one case was PRL-producing chromophobe adenoma. No stigmata of neurofibromatosis or any history of irradiation was found. Compression of carotid arteries by the tumor was unlikely. These cases should therefore be classified as moyamoya disease accompanied by brain tumor, a very rare occurrence. The hypothalamic disturbance caused by moyamoya disease may have induced the hyperprolactinemia, resulting in secondary prolactinoma.

[1]  K. Suyama,et al.  A case of recurrent optic glioma presenting with moyamoya vascularity. , 1990 .

[2]  A. Yamaura,et al.  [Neurofibromatosis with occlusion of internal carotid artery and malignant astrocytoma. Case report]. , 1987, Neurologia medico-chirurgica.

[3]  S. Miyamoto,et al.  [Visual disturbances in moyamoya disease]. , 1986, No to shinkei = Brain and nerve.

[4]  M. Gado,et al.  The moyamoya syndrome associated with irradiation of an optic glioma in children: report of two cases and review of the literature. , 1985, Pediatric neurology.

[5]  W. Montanera,et al.  Meningioma and occlusive vasculopathy: coexisting complications of past extracranial radiation. , 1985, Surgical neurology.

[6]  N. Kodama,et al.  [A case of radiation necrosis with vascular changes on main cerebral arteries (author's transl)]. , 1982, No shinkei geka. Neurological surgery.

[7]  S. DeArmond,et al.  Radiation-induced large intracranial vessel occlusive vasculopathy. , 1980, AJR. American journal of roentgenology.

[8]  H. Handa,et al.  "Moyamoya" vessels on the tumor in the sellar region. , 1979, Nihon geka hokan. Archiv fur japanische Chirurgie.

[9]  A. Raimondi,et al.  Childhood Moyamoya Syndrome , 1979 .

[10]  L. Cerullo,et al.  Childhood moyamoya syndrome. Postradiation pathogenesis. , 1979, Child's brain.

[11]  M. Mikhael,et al.  Cerebrovascular Changes in Neurofibromatosis , 1978, Developmental medicine and child neurology.

[12]  E. Klaus,et al.  Neurofibromatosis v. Recklinghausen mit intrakranialer Stenose der A. carotis interna bei orbito-sphenoidaler Knochendysplasie , 1978 .

[13]  H. Handa,et al.  Occlusive arteriopathy and brain tumor. , 1978, Journal of neurosurgery.

[14]  A. Servo,et al.  Moyamoya syndrome as a complication of radiation therapy. Case report. , 1978, Journal of neurosurgery.

[15]  E. Franken,et al.  The radiographic spectrum in neurofibromatosis. , 1976, Seminars in roentgenology.

[16]  S. Hilal,et al.  Cerebrovasculopathy following irradiation in childhood , 1975, Neurology.

[17]  K. Iwatsuki,et al.  [Case of cerebral basal rete mirable associated with brain tumor]. , 1973, Rinsho shinkeigaku = Clinical neurology.

[18]  S. Hilal,et al.  Primary Cerebral Arterial Occlusive Disease in Children , 1971 .

[19]  S. Hilal,et al.  Primary cerebral arterial occlusive disease in children. II. Neurocutaneous syndromes. , 1971, Radiology.

[20]  A Takaku,et al.  Cerebrovascular "moyamoya" disease. Disease showing abnormal net-like vessels in base of brain. , 1969, Archives of neurology.

[21]  A. Nishimoto,et al.  Abnormal cerebrovascular network related to the internal cartoid arteries. , 1968, Journal of neurosurgery.

[22]  T. Kudo.  Spontaneous occlusion of the circle of Willis , 1968, Neurology.

[23]  K. F. Lee,et al.  INTRACRANIAL ISCHEMIC LESIONS , 1967, Radiologic Clinics of North America.

[24]  E. S. Gurdjian,et al.  Postirradiation vascular insufficiency syndrome , 1967, Neurology.

[25]  K. Ueki,et al.  [Evaluation of a group of cases presenting an abnormal vascular network at the base of the brain]. , 1966, No to shinkei = Brain and nerve.