Amino acid periodicities and their structural implications for the evolutionarily conservative central domain of some silkmoth chorion proteins.

The central domain is an evolutionarily conservative region that is invariant in length in the A and Hc-A families of silkmoth chorion proteins. This domain shows strong sixfold periodicities for various amino acid residues, such as glycine and large non-polar residues. The periodicities and their phase relationships, together with the documented prevalence of beta-sheets and beta-turns in the chorion, strongly support a secondary structure model in which short (4-residue) beta-sheet strands alternate with beta-turns, forming a compact antiparallel, probably twisted beta-sheet. This structure should be important for the establishment of higher order structure in the chorion.

[1]  D. Smith,et al.  Fine structure of the chorion of a moth, hyalophora cecropia. , 1971, Tissue & cell.

[2]  Y Bouligand,et al.  Twisted fibrous arrangements in biological materials and cholesteric mesophases. , 1972, Tissue & cell.

[3]  T. Eickbush,et al.  A walk in the chorion locus of bombyx mori , 1982, Cell.

[4]  F. Kafatos,et al.  Morphogenesis of silkmoth chorion: initial framework formation and its relation to synthesis of specific proteins. , 1982, Developmental biology.

[5]  S. Hamodrakas,et al.  X-ray diffraction studies of a silkmoth chorion , 1983 .

[6]  S. Hamodrakas.  Twisted β-pleated sheet: the molecular conformation which possibly dictates the formation of the helicoidal architecture of several proteinaceous eggshells , 1984 .

[7]  P. Y. Chou,et al.  Conservation of chain reversal regions in proteins. , 1979, Biophysical journal.

[8]  Cyrus Chothia,et al.  Conformation of twisted β-pleated sheets in proteins , 1973 .

[9]  R. Boswell.  Embryogenesis and reproduction , 1985 .

[10]  S. Hamodrakas,et al.  Laser-Raman spectroscopic studies of the eggshell (chorion) of Bombyx mori , 1984 .

[11]  J. Richardson,et al.  β-Sheet topology and the relatedness of proteins , 1977, Nature.

[12]  F. Kafatos,et al.  Developmentally regulated genes in silkmoths. , 1984, Annual review of genetics.

[13]  F. Kafatos,et al.  Structure, organization and evolution of developmentally regulated chorion genes in a silkmoth , 1980, Cell.

[14]  A. Mclachlan,et al.  The 14-fold periodicity in α-tropomyosin and the interaction with actin , 1976 .

[15]  N. Rosenthal,et al.  Evolution of two major chorion multigene families as inferred from cloned cDNA and protein sequences , 1979, Cell.

[16]  A. Dunker,et al.  Determination of the secondary structure of proteins from the amide I band of the laser Raman spectrum. , 1981, Journal of molecular biology.

[17]  H. Blau,et al.  Morphogenesis of the silkmoth chorion: patterns of distribution and insolubilization of the structural proteins. , 1979, Developmental biology.

[18]  F. Kafatos,et al.  Evolution of a multigene family of chorion proteins in silkmoths , 1982, Molecular and cellular biology.

[19]  S. Hamodrakas,et al.  Secondary structure predictions for silkmoth chorion proteins , 1982 .

[20]  F. Kafatos,et al.  Selection and sequence analysis of a cDNA clone encoding a known chorion protein of the A family. , 1980, Nucleic acids research.

[21]  A. Mclachlan,et al.  Analysis of periodic patterns in amino acid sequences: Collagen , 1977, Biopolymers.

[22]  G. A. Kerkut,et al.  Comprehensive insect physiology, biochemistry, and pharmacology , 1985 .

[23]  R. Bear,et al.  Disclosure by Fourier methods of a long-range pattern of non-polar residues in the alpha1(I) sequence of collagen. , 1978, Journal of molecular biology.

[24]  G. G. Stokes.  "J." , 1890, The New Yale Book of Quotations.

[25]  S. Hamodrakas,et al.  Laser Raman studies of protein conformation in the silkmoth chorion. , 1982, Biochimica et biophysica acta.

[26]  S. Subtelny,et al.  Gene structure and regulation in development , 1983 .

[27]  N M Green,et al.  Evidence for a repeating cross‐beta sheet structure in the adenovirus fibre. , 1983, The EMBO journal.

[28]  F. Kafatos,et al.  The silkmoth chorion: morphological and biochemical characterization of four surface regions. , 1980, Developmental biology.

[29]  B. Lotz,et al.  Twisted single crystals of Bombyx mori silk fibroin and related model polypeptides with beta structure. A correlation with the twist of the beta sheets in globular proteins. , 1982, Journal of molecular biology.