Calcium-dependent energetics of calmodulin domain interactions with regulatory regions of the Ryanodine Receptor Type 1 (RyR1).

[1]  Kelvin Lau,et al.  Lobe-specific calmodulin binding to different ryanodine receptor isoforms. , 2014, Biochemistry.

[2]  T. Wagenknecht,et al.  Calmodulin-binding Locations on the Skeletal and Cardiac Ryanodine Receptors* , 2012, The Journal of Biological Chemistry.

[3]  M. A. Shea,et al.  Recognition of β–calcineurin by the domains of calmodulin: Thermodynamic and structural evidence for distinct roles , 2011, Proteins.

[4]  M. A. Shea,et al.  Energetics of calmodulin domain interactions with the calmodulin binding domain of CaMKII , 2009, Proteins.

[5]  David D. Thomas,et al.  FRET-based mapping of calmodulin bound to the RyR1 Ca2+ release channel , 2009, Proceedings of the National Academy of Sciences.

[6]  M. A. Shea,et al.  Interdomain cooperativity of calmodulin bound to melittin preferentially increases calcium affinity of sites I and II , 2008, Proteins.

[7]  C. Boschek,et al.  Different conformational switches underlie the calmodulin-dependent modulation of calcium pumps and channels. , 2008, Biochemistry.

[8]  M. A. Shea,et al.  The neuronal voltage-dependent sodium channel type II IQ motif lowers the calcium affinity of the C-domain of calmodulin. , 2008, Biochemistry.

[9]  C. Boschek,et al.  Calcium occupancy of N-terminal sites within calmodulin induces inhibition of the ryanodine receptor calcium release channel. , 2007, Biochemistry.

[10]  G. Carlson,et al.  Single molecule analyses of the conformational substates of calmodulin bound to the phosphorylase kinase complex , 2007, Protein science : a publication of the Protein Society.

[11]  M. A. Shea,et al.  Calcium binding to calmodulin mutants having domain-specific effects on the regulation of ion channels. , 2006, Biochemistry.

[12]  Y. Shamoo,et al.  Complex of calmodulin with a ryanodine receptor target reveals a novel, flexible binding mode. , 2006, Structure.

[13]  D. Bers,et al.  Dynamic changes in free Ca-calmodulin levels in adult cardiac myocytes. , 2006, Journal of molecular and cellular cardiology.

[14]  G. Meissner,et al.  Calmodulin regulation and identification of calmodulin binding region of type-3 ryanodine receptor calcium release channel. , 2005, Biochemistry.

[15]  David D. Thomas,et al.  Direct detection of calmodulin tuning by ryanodine receptor channel targets using a Ca2+-sensitive acrylodan-labeled calmodulin. , 2005, Biochemistry.

[16]  Bo Wang,et al.  Biochemical properties of V91G calmodulin: A calmodulin point mutation that deregulates muscle contraction in Drosophila , 2004, Protein science : a publication of the Protein Society.

[17]  R. Kass,et al.  Calmodulin Mediates Ca2+ Sensitivity of Sodium Channels* , 2004, Journal of Biological Chemistry.

[18]  A. Persechini,et al.  Monitoring the total available calmodulin concentration in intact cells over the physiological range in free Ca2+. , 2004, Cell calcium.

[19]  J. Hell,et al.  Apo-Calmodulin Binds with its C-terminal Domain to the N-Methyl-d-aspartate Receptor NR1 C0 Region* , 2004, Journal of Biological Chemistry.

[20]  A. R. Penheiter,et al.  A model for the activation of plasma membrane calcium pump isoform 4b by calmodulin. , 2003, Biochemistry.

[21]  Ad Bax,et al.  Calcium Dependence of the Interaction between Calmodulin and Anthrax Edema Factor* , 2003, Journal of Biological Chemistry.

[22]  G. Meissner,et al.  Molecular Basis of Calmodulin Binding to Cardiac Muscle Ca2+ Release Channel (Ryanodine Receptor)* , 2003, Journal of Biological Chemistry.

[23]  S. Hamilton,et al.  A Noncontiguous, Intersubunit Binding Site for Calmodulin on the Skeletal Muscle Ca2+ Release Channel* , 2003, The Journal of Biological Chemistry.

[24]  J. Johnson,et al.  Regulation of the RYR1 and RYR2 Ca2+ release channel isoforms by Ca2+-insensitive mutants of calmodulin. , 2003, Biochemistry.

[25]  M. A. Shea,et al.  Calcium binding to calmodulin mutants monitored by domain-specific intrinsic phenylalanine and tyrosine fluorescence. , 2002, Biophysical journal.

[26]  M. A. Shea,et al.  Lobe-dependent Regulation of Ryanodine Receptor Type 1 by Calmodulin* , 2002, The Journal of Biological Chemistry.

[27]  A. Nairn,et al.  A Direct Test of the Reductionist Approach to Structural Studies of Calmodulin Activity , 2002, The Journal of Biological Chemistry.

[28]  Mitsuhiko Ikura,et al.  Calmodulin in Action Diversity in Target Recognition and Activation Mechanisms , 2002, Cell.

[29]  A. Bohm,et al.  Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin , 2002, Nature.

[30]  Montserrat Samsó,et al.  Apocalmodulin and Ca2+-Calmodulin Bind to Neighboring Locations on the Ryanodine Receptor* , 2002, The Journal of Biological Chemistry.

[31]  M. A. Shea,et al.  An interdomain linker increases the thermostability and decreases the calcium affinity of the calmodulin N-domain. , 2002, Biochemistry.

[32]  S. Hamilton,et al.  The carboxy-terminal calcium binding sites of calmodulin control calmodulin's switch from an activator to an inhibitor of RYR1. , 2001, Biochemistry.

[33]  G. Meissner,et al.  Identification of Apocalmodulin and Ca2+-Calmodulin Regulatory Domain in Skeletal Muscle Ca2+ Release Channel, Ryanodine Receptor* , 2001, The Journal of Biological Chemistry.

[34]  J. Adelman,et al.  Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin , 2001, Nature.

[35]  M. A. Shea,et al.  Paramecium calmodulin mutants defective in ion channel regulation associate with melittin in the absence of calcium but require it for tertiary collapse. , 2001, Biochemistry.

[36]  S. Hamilton,et al.  Calcium Binding to Calmodulin Leads to an N-terminal Shift in Its Binding Site on the Ryanodine Receptor* , 2001, The Journal of Biological Chemistry.

[37]  S. Hamilton,et al.  Regulation of RYR1 activity by Ca(2+) and calmodulin. , 2000, Biochemistry.

[38]  S. Hamilton,et al.  A Role for Cysteine 3635 of RYR1 in Redox Modulation and Calmodulin Binding* , 1999, The Journal of Biological Chemistry.

[39]  S. Hamilton,et al.  Apocalmodulin and Ca2+ calmodulin bind to the same region on the skeletal muscle Ca2+ release channel. , 1999, Biochemistry.

[40]  M P Walsh,et al.  Calcium-dependent and -independent interactions of the calmodulin-binding domain of cyclic nucleotide phosphodiesterase with calmodulin. , 1999, Biochemistry.

[41]  H. Vogel,et al.  Characterization of the Ca2+‐dependent and ‐independent interactions between calmodulin and its binding domain of inducible nitric oxide synthase , 1998, FEBS letters.

[42]  M. A. Shea,et al.  Interactions between domains of apo calmodulin alter calcium binding and stability. , 1998, Biochemistry.

[43]  M Ikura,et al.  Identification of Mg2+-binding sites and the role of Mg2+ on target recognition by calmodulin. , 1997, Biochemistry.

[44]  J. Falke,et al.  Intermolecular tuning of calmodulin by target peptides and proteins: Differential effects on Ca2+ binding and implications for kinase activation , 1997, Protein science : a publication of the Protein Society.

[45]  S. Martin,et al.  Target recognition by calmodulin: Dissecting the kinetics and affinity of interaction using short peptide sequences , 1996, Protein science : a publication of the Protein Society.

[46]  D. Blumenthal,et al.  Characterization of the regulatory domain of the gamma-subunit of phosphorylase kinase. The two noncontiguous calmodulin-binding subdomains are also autoinhibitory. , 1995, The Journal of biological chemistry.

[47]  H. Vogel,et al.  Interaction of Calmodulin with Its Binding Domain of Rat Cerebellar Nitric Oxide Synthase , 1995, The Journal of Biological Chemistry.

[48]  L. Xu,et al.  Calmodulin activation and inhibition of skeletal muscle Ca2+ release channel (ryanodine receptor). , 1995, Biophysical journal.

[49]  M. A. Shea,et al.  Quantitative endoproteinase GluC footprinting of cooperative Ca2+ binding to calmodulin: proteolytic susceptibility of E31 and E87 indicates interdomain interactions. , 1995, Biochemistry.

[50]  A. Mújica,et al.  Calmodulin binding proteins in the membrane vesicles released during the acrosome reaction and in the perinuclear material in isolated acrosome reacted sperm heads. , 1994, Tissue & cell.

[51]  J. Falke,et al.  Molecular Tuning of Ion Binding to Calcium Signaling Proteins , 1994, Quarterly Reviews of Biophysics.

[52]  S. Ohki,et al.  Mg2+ inhibits formation of 4Ca(2+)-calmodulin-enzyme complex at lower Ca2+ concentration. 1H and 113Cd NMR studies. , 1993, The Journal of biological chemistry.

[53]  M Ikura,et al.  Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible. , 1992, Biochemistry.

[54]  P. Kraulis A program to produce both detailed and schematic plots of protein structures , 1991 .

[55]  D. Blumenthal,et al.  Small-angle scattering studies show distinct conformations of calmodulin in its complexes with two peptides based on the regulatory domain of the catalytic subunit of phosphorylase kinase. , 1990, Biochemistry.

[56]  D. Blumenthal,et al.  The gamma-subunit of skeletal muscle phosphorylase kinase contains two noncontiguous domains that act in concert to bind calmodulin. , 1989, The Journal of biological chemistry.

[57]  M. Ikura,et al.  113Cd-NMR evidence for cooperative interaction between amino- and carboxyl-terminal domains of calmodulin. , 1989, Biochemical and biophysical research communications.

[58]  C. Bugg,et al.  Structure of calmodulin refined at 2.2 A resolution. , 1988, Journal of molecular biology.

[59]  C. L. Wang,et al.  A note on Ca2+ binding to calmodulin. , 1985, Biochemical and biophysical research communications.

[60]  A. Means,et al.  Bacterial expression and characterization of proteins derived from the chicken calmodulin cDNA and a calmodulin processed gene. , 1985, The Journal of biological chemistry.

[61]  M. A. Shea,et al.  Free energy coupling within macromolecules. The chemical work of ligand binding at the individual sites in co-operative systems. , 1983, Journal of molecular biology.

[62]  M. Ikura,et al.  Nuclear magnetic resonance studies on calmodulin: calcium-induced conformational change. , 1983, Biochemistry.

[63]  K. Sobue,et al.  Quantitative determinations of calmodulin in the supernatant and particulate fractions of mammalian tissues. , 1982, Journal of biochemistry.

[64]  J Haiech,et al.  Effects of cations on affinity of calmodulin for calcium: ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. , 1981, Biochemistry.

[65]  C. Klee,et al.  Specific perturbation by Ca2+ of tyrosyl residue 138 of calmodulin. , 1979, The Journal of biological chemistry.

[66]  G. Adair,et al.  The osmotic pressure of hæmoglobin in the absence of salts , 1925 .

[67]  S. Hamilton,et al.  A Ca2+-binding domain in RyR1 that interacts with the calmodulin binding site and modulates channel activity. , 2006, Biophysical journal.

[68]  C. Kung,et al.  Calmodulin as an ion channel subunit. , 2002, Annual review of physiology.

[69]  M. A. Shea,et al.  Proteolytic footprinting titrations for estimating ligand-binding constants and detecting pathways of conformational switching of calmodulin. , 2000, Methods in enzymology.

[70]  S. Martin,et al.  Enhancement by Mg2+ of domain specificity in Ca2+‐dependent interactions of calmodulin with target sequences , 2000, Protein science : a publication of the Protein Society.

[71]  E A Merritt,et al.  Raster3D: photorealistic molecular graphics. , 1997, Methods in enzymology.

[72]  M Ikura,et al.  Molecular and structural basis of target recognition by calmodulin. , 1995, Annual review of biophysics and biomolecular structure.

[73]  Michael L. Johnson,et al.  [16] Nonlinear least-squares analysis , 1985 .

[74]  R. Klevit [8] Spectroscopic analyses of calmodulin and its interactions , 1983 .

[75]  G. H. Beaven,et al.  Ultraviolet absorption spectra of proteins and amino acids. , 1952, Advances in protein chemistry.