Benign Epilepsy with Centro‐temporal Spikes: Spike Triggered fMRI Shows Somato‐sensory Cortex Activity

Summary:  Objective: We performed spike triggered functional MRI (fMRI) in a 12 year old girl with Benign Epilepsy with Centro‐temporal Spikes (BECTS) and left‐sided spikes. Our aim was to demonstrate the cerebral origin of her interictal spikes.

[1]  P. Wong,et al.  Topographical Analysis of the Centrotemporal Discharges in Benign Rolandic Epilepsy of Childhood , 1984, Epilepsia.

[2]  S. Blom,et al.  Benign Epilepsy of Children with Centrotemporal EEG Foci: A Follow‐up Study in Adulthood of Patients Initially Studied as Children , 1982, Epilepsia.

[3]  A. Maravita,et al.  Spike topography and functional magnetic resonance imaging (fMRI) in benign rolandic epilepsy with spikes evoked by tapping stimulation. , 1998, Electroencephalography and clinical neurophysiology.

[4]  N. Logothetis,et al.  Neurophysiological investigation of the basis of the fMRI signal , 2001, Nature.

[5]  J R Ives,et al.  EEG-triggered echo-planar functional MRI in epilepsy , 1996, Neurology.

[6]  P. Loiseau,et al.  The Seizures of Benign Childhood Epilepsy with Rolandic Paroxysmal Discharges , 1973, Epilepsia.

[7]  Afraim Salek-Haddadi,et al.  Event-Related fMRI with Simultaneous and Continuous EEG: Description of the Method and Initial Case Report , 2001, NeuroImage.

[8]  Louis Lemieux,et al.  Identification of EEG Events in the MR Scanner: The Problem of Pulse Artifact and a Method for Its Subtraction , 1998, NeuroImage.

[9]  O. Arthurs,et al.  How well do we understand the neural origins of the fMRI BOLD signal? , 2002, Trends in Neurosciences.

[10]  D. Tank,et al.  Brain magnetic resonance imaging with contrast dependent on blood oxygenation. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[11]  M. Posner,et al.  Cognitive and emotional influences in anterior cingulate cortex , 2000, Trends in Cognitive Sciences.

[12]  P. Strick,et al.  Motor areas of the medial wall: a review of their location and functional activation. , 1996, Cerebral cortex.

[13]  M R Symms,et al.  EEG-triggered functional MRI of interictal epileptiform activity in patients with partial seizures. , 1999, Brain : a journal of neurology.

[14]  Peter Kellaway,et al.  The Electroencephalographic Features of Benign Centrotemporal (Rolandic) Epilepsy of Childhood , 2000, Epilepsia.

[15]  P. Lerman Benign partial epilepsy with centro-temporal spikes , 1992 .

[16]  C M Michel,et al.  EEG‐Triggered Functional MRI in Patients With Pharmacoresistant Epilepsy , 2000, Journal of magnetic resonance imaging : JMRI.