Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
暂无分享,去创建一个
[1] C. Der,et al. Two Distinct Raf Domains Mediate Interaction with Ras (*) , 1995, The Journal of Biological Chemistry.
[2] M. Wigler,et al. Multiple ras functions can contribute to mammalian cell transformation , 1995, Cell.
[3] J. Bischoff,et al. Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[4] S. Fields,et al. Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[5] C. Der,et al. R-Ras induces malignant, but not morphologic, transformation of NIH3T3 cells. , 1994, Oncogene.
[6] S. Demo,et al. ralGDS family members interact with the effector loop of ras p21 , 1994, Molecular and cellular biology.
[7] M. Wigler,et al. Cooperative interaction of S. pombe proteins required for mating and morphogenesis , 1994, Cell.
[8] C. Der,et al. Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras , 1994, Molecular and cellular biology.
[9] Michael J. Fry,et al. Phosphatidylinositol-3-OH kinase direct target of Ras , 1994, Nature.
[10] N. Ahn,et al. Transformation of mammalian cells by constitutively active MAP kinase kinase. , 1994, Science.
[11] S. Bagrodia,et al. Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. , 1994, The Journal of biological chemistry.
[12] D. Brenner,et al. Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[13] C. Marshall,et al. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells , 1994, Cell.
[14] P. D’Eustachio,et al. Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation. , 1994, Molecular and cellular biology.
[15] J. Avruch,et al. Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation. , 1994, The Journal of biological chemistry.
[16] S. Aaronson,et al. Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. , 1994, The Journal of biological chemistry.
[17] C. Hauser,et al. Transcriptional activation analysis of oncogene function. , 1994, Methods in enzymology.
[18] Mark S. Boguski,et al. Proteins regulating Ras and its relatives , 1993, Nature.
[19] K. Fujisawa,et al. ADP-ribosylation of rho p21 inhibits lysophosphatidic acid-induced protein tyrosine phosphorylation and phosphatidylinositol 3-kinase activation in cultured Swiss 3T3 cells. , 1993, The Journal of biological chemistry.
[20] D. Morrison,et al. Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase , 1993, Molecular and cellular biology.
[21] R. Weinberg,et al. The pathway to signal achievement , 1993, Nature.
[22] J. Pouysségur,et al. Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[23] T. Pawson,et al. The N‐terminal region of GAP regulates cytoskeletal structure and cell adhesion. , 1993, The EMBO journal.
[24] S. Y. Cajal,et al. Tumorigenic activity of rho genes from Aplysia californica. , 1993, Oncogene.
[25] M. Cobb,et al. Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. , 1993, The Journal of biological chemistry.
[26] A. Hall,et al. Different structural organization of Ras and Rho effector domains. , 1993, Oncogene.
[27] R. Weinberg,et al. Characterization of a guanine nucleotide dissociation stimulator for a ras‐related GTPase. , 1993, The EMBO journal.
[28] G. Prendergast,et al. Pathways of Ras function: connections to the actin cytoskeleton. , 1993, Advances in cancer research.
[29] T. M. Roberts. A signal chain of events , 1992, Nature.
[30] C. Der,et al. Ras ( CXXX ) and Rab ( CClCXC ) Prenylation Signal Sequences Are Unique and Functionally Distinct * , 2001 .
[31] P. Goldschmidt-Clermont,et al. Rac and Rho in control , 1992, Current Biology.
[32] K. Burridge,et al. What the papers say. Rho, rac and the actin cytoskeleton , 1992 .
[33] C. Marshall,et al. MAP kinase regulation--the oncogene connection. , 1992, Trends in cell biology.
[34] Anne J. Ridley,et al. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling , 1992, Cell.
[35] Anne J. Ridley,et al. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.
[36] R. Weinberg,et al. Molecular cloning of cDNAs encoding the GAP-associated protein p190: Implications for a signaling pathway from ras to the nucleus , 1992, Cell.
[37] A. Hall,et al. Ras-related GTPases and the cytoskeleton. , 1992, Molecular biology of the cell.
[38] U. Rapp,et al. Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase. , 1992, Genes & development.
[39] K. Burridge,et al. Rho, rac and the actin cytoskeleton. , 1992, BioEssays : news and reviews in molecular, cellular and developmental biology.
[40] S. Aaronson,et al. Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product , 1991, Nature.
[41] M. Moran,et al. Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein , 1991, Molecular and cellular biology.
[42] W. Kolch,et al. Raf-1 protein kinase is required for growth of induced NIH/3T3 cells , 1991, Nature.
[43] Frank McCormick,et al. The GTPase superfamily: a conserved switch for diverse cell functions , 1990, Nature.
[44] R. Weinberg,et al. Characterization and expression of the human rhoH12 gene product , 1989, Molecular and cellular biology.
[45] G. Cooper,et al. Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP , 1988, Molecular and cellular biology.
[46] C. Der,et al. Biological and biochemical properties of human ras H genes mutated at codon 61 , 1986, Cell.
[47] R. Gaylord. unpublished results , 1985 .