Dihydrolipoic acid--a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals.

[1]  J. Prehn,et al.  Dihydrolipoate Reduces Neuronal Injury after Cerebral Ischemia , 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[2]  L. Packer,et al.  Ultraviolet light-induced generation of vitamin E radicals and their recycling. A possible photosensitizing effect of vitamin E in skin. , 1992, Free radical research communications.

[3]  S. Pagani,et al.  Uptake of iron by apoferritin from a ferric dihydrolipoate complex. , 1991, European journal of biochemistry.

[4]  L. Trümper,et al.  Morphological changes of isolated rat liver mitochondria during Fe2+/ascorbate-induced peroxidation and the effect of thioctacid , 1991, Mechanisms of Ageing and Development.

[5]  R. Mehlhorn Ascorbate- and dehydroascorbic acid-mediated reduction of free radicals in the human erythrocyte. , 1991, The Journal of biological chemistry.

[6]  A. Bast,et al.  Interplay between vitamin E, glutathione and dihydrolipoic acid in protection against lipid peroxidation , 1991 .

[7]  L. Packer,et al.  Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. , 1991, Free radical research communications.

[8]  U. Nagashima,et al.  Kinetic and ab initio study of the prooxidant effect of vitamin E. Hydrogen abstraction from fatty acid esters and egg yolk lecithin , 1990 .

[9]  L. Packer,et al.  Recycling and antioxidant activity of tocopherol homologs of differing hydrocarbon chain lengths in liver microsomes. , 1990, Archives of biochemistry and biophysics.

[10]  G. Stoltenburg‐Didinger,et al.  Effects of lipoic acid in hexacarbon-induced neuropathy. , 1990, Neurotoxicology and teratology.

[11]  L. Packer,et al.  Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling. , 1990, Biochemical and biophysical research communications.

[12]  R. C. Rose Ascorbic acid metabolism in protection against free radicals: a radiation model. , 1990, Biochemical and biophysical research communications.

[13]  H. Menzel,et al.  Studies on the efficacy of lipoate and dihydrolipoate in the alteration of cadmium2+ toxicity in isolated hepatocytes. , 1990, Biochimica et biophysica acta.

[14]  W. Piering,et al.  Role of the clinical laboratory in guiding treatment of Amanita virosa mushroom poisoning: report of two cases. , 1990, Clinical chemistry.

[15]  R. Mason,et al.  Glutathione and ascorbate reduction of the acetaminophen radical formed by peroxidase. Detection of the glutathione disulfide radical anion and the ascorbyl radical. , 1990, The Journal of biological chemistry.

[16]  R. Willson,et al.  Hydrogen peroxide cytotoxicity. Low-temperature enhancement by ascorbate or reduced lipoate. , 1989, The Biochemical journal.

[17]  R. Mason,et al.  Lipid peroxyl radical intermediates in the peroxidation of polyunsaturated fatty acids by lipoxygenase. Direct electron spin resonance investigations. , 1989, The Journal of biological chemistry.

[18]  C. C. Reddy,et al.  Mechanism of Interaction of Vitamin E and Glutathione in the Protection against Membrane Lipid Peroxidation , 1989 .

[19]  P. McCay,et al.  Evidence That Alpha‐Tocopherol Functions Cyclically to Quench Free Radicals in Hepatic Microsomes Requirement for Glutathione and a Heat‐Labile Factor , 1989, Annals of the New York Academy of Sciences.

[20]  L. Müller Protective effects of DL-α-lipoic acid on cadmium-induced deterioration of rat hepatocytes , 1989 .

[21]  A. Glazer,et al.  Phycoerythrin fluorescence-based assay for peroxy radicals: a screen for biologically relevant protective agents. , 1989, Analytical biochemistry.

[22]  L. Packer,et al.  Mitochondria and microsomal membranes have a free radical reductase activity that prevents chromanoxyl radical accumulation. , 1989, Biochemical and biophysical research communications.

[23]  H. Sies,et al.  Antioxidant activity of dihydrolipoate against microsomal lipid peroxidation and its dependence on alpha-tocopherol. , 1989, Biochimica et biophysica acta.

[24]  S. Pagani,et al.  Molecular aspects of the removal of ferritin-bound iron by DL-dihydrolipoate. , 1989, Biochimica et biophysica acta.

[25]  A. Bast,et al.  Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. , 1988, Biochimica et biophysica acta.

[26]  V. Kagan Lipid Peroxidation In Biomembranes , 1988 .

[27]  H. Sies,et al.  The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E. , 1988, European journal of biochemistry.

[28]  J. Jörg,et al.  [Drug treatment of diabetic polyneuropathy with alpha-lipoic acid or vitamin B preparations. A clinical and neurophysiologic study]. , 1988, Der Nervenarzt.

[29]  M. Bando,et al.  Ascorbate free radical reductase and ascorbate redox cycle in the human lens. , 1988, Japanese journal of ophthalmology.

[30]  B. S. Winkler In vitro oxidation of ascorbic acid and its prevention by GSH. , 1987, Biochimica et biophysica acta.

[31]  L. Packer,et al.  Simultaneous determination of tocopherols, ubiquinols, and ubiquinones in blood, plasma, tissue homogenates, and subcellular fractions. , 1986, Analytical biochemistry.

[32]  S. Pagani,et al.  Removal of ferritin-bound iron by DL-dihydrolipoate and DL-dihydrolipoamide. , 1986, European journal of biochemistry.

[33]  E. Niki,et al.  Damage to biological tissues induced by radical initiator 2,2'-azobis(2-amidinopropane) dihydrochloride and its inhibition by chain-breaking antioxidants. , 1986, Journal of free radicals in biology & medicine.

[34]  B. Halliwell,et al.  Free radicals in biology and medicine , 1985 .

[35]  A. Bast,et al.  Cytochrome P-450 and glutathione: what is the significance of their interrelationship in lipid peroxidation? , 1984 .

[36]  R. Burk,et al.  Influence of vitamin E and selenium on glutathione-dependent protection against microsomal lipid peroxidation. , 1984, Biochemical pharmacology.

[37]  A. Bast,et al.  Protection against lipid peroxidation by a microsomal glutathione‐dependent labile factor , 1983, FEBS letters.

[38]  R. Burk,et al.  Glutathione-dependent protection by rat liver microsomal protein against lipid peroxidation. , 1983, Biochimica et biophysica acta.

[39]  C. C. Reddy,et al.  Vitamin E dependent reduced glutathione inhibition of rat liver microsomal lipid peroxidation. , 1982, Life sciences.

[40]  E. Niki,et al.  REGENERATION OF VITAMIN E FROM α-CHROMANOXYL RADICAL BY GLUTATHIONE AND VITAMIN C , 1982 .

[41]  R. Burk,et al.  Rat hepatic cytosolic glutathione-dependent enzyme protection against lipid peroxidation in the NADPH-microsomal lipid peroxidation system. , 1980, Biochimica et biophysica acta.

[42]  J. Packer,et al.  Direct observation of a free radical interaction between vitamin E and vitamin C , 1979, Nature.

[43]  S. Aust,et al.  Microsomal lipid peroxidation. , 1978, Methods in enzymology.

[44]  P. McCray,et al.  Effect of glutathione peroxidase activity on lipid peroxidation in biological membranes. , 1976, Biochimica et biophysica acta.

[45]  V. Ekstrand,et al.  PURIFICATION AND PROPERTIES OF GLUTATHIONE REDUCTASE OF HUMAN ERYTHROCYTES. , 1963, The Journal of biological chemistry.

[46]  D. Sanadi,et al.  alpha-Ketoglutaric dehydrogenase. 8. Isolation and some properties of a flavoprotein compnent. , 1960, The Journal of biological chemistry.