Convolutamydine A, a novel bioactive hydroxyoxindole alkaloid from marine bryozoan Amathia convoluta

Abstract Convolutamydine A ( 1 ), a new alkaloid containing a dibromohydroxyoxindole moiety, was isolated from the Floridian bryozoan Amathia convoluta and the structure was elucidated on the basis of spectroscopic data. Compound 1 exhibited a potent activity in the differentiation of HL-60 cells.