Computational model of carbachol‐induced delta, theta, and gamma oscillations in the hippocampus

Field potential recordings from the rat hippocampus in vivo contain distinct frequency bands of activity, including δ (0.5–2 Hz), θ (4–12 Hz), and γ (30–80 Hz), that are correlated with the behavioral state of the animal. The cholinergic agonist carbachol (CCH) induces oscillations in the δ (CCH‐δ), θ (CCH‐θ), and γ (CCH‐γ) frequency ranges in the hippocampal slice preparation, eliciting asynchronous CCH‐θ, synchronous CCH‐δ, and synchronous CCH‐θ with increasing CCH concentration (Fellous and Sejnowski, Hippocampus 2000;10:187–197).

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