Enhanced solubility and dissolution of simvastatin by HPMC-based solid dispersions prepared by hot melt extrusion and spray-drying method

[1]  Jiju Antony,et al.  6 – Full Factorial Designs , 2014 .

[2]  P. Amin,et al.  Formulation of highly purified fenugreek gum based silica lipid drug delivery system for simvastatin with enhanced dissolution rate and in vitro characterization , 2013, Journal of Pharmaceutical Investigation.

[3]  Siling Wang,et al.  Enhanced dissolution rate and oral bioavailability of simvastatin nanocrystal prepared by sonoprecipitation , 2012, Drug development and industrial pharmacy.

[4]  Ya,et al.  Formulation, Optimization and characterization of Simvastatin Nanosuspension prepared by nanoprecipitation technique , 2011 .

[5]  Kamla Pathak,et al.  Development and Statistical Optimization of Solid Lipid Nanoparticles of Simvastatin by Using 23 Full-Factorial Design , 2010, AAPS PharmSciTech.

[6]  Stefan Radl,et al.  A novel design for hot-melt extrusion pelletizers , 2010 .

[7]  P. Ojha,et al.  Effect of Carriers on Solid Dispersions of Simvastatin (Sim): Physico-Chemical Characterizations and Dissolution Studies , 2010 .

[8]  S. Gattani,et al.  Co-solvent Evaporation Method for Enhancement of Solubility and Dissolution Rate of Poorly Aqueous Soluble Drug Simvastatin: In vitro–In vivo Evaluation , 2008, AAPS PharmSciTech.

[9]  A. Voilley,et al.  Applications of spray-drying in microencapsulation of food ingredients: An overview , 2007 .

[10]  S. Brun,et al.  The Tablet Formulation of Lopinavir/Ritonavir Provides Similar Bioavailability to the Soft-Gelatin Capsule Formulation With Less Pharmacokinetic Variability and Diminished Food Effect , 2007, Journal of acquired immune deficiency syndromes.

[11]  A. Paradkar,et al.  Formulation of a self-emulsifying system for oral delivery of simvastatin: In vitro and in vivo evaluation , 2007, Acta pharmaceutica.

[12]  Wei Yang,et al.  Hot-melt extrusion for enhanced delivery of drug particles. , 2007, Journal of pharmaceutical sciences.

[13]  M. Nagarsenker,et al.  Dry Adsorbed Emulsion of Simvastatin: Optimization and In Vivo Advantage , 2007, Pharmaceutical development and technology.

[14]  J. Breitenbach.  Melt extrusion: from process to drug delivery technology. , 2002, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[15]  D. Craig,et al.  The mechanisms of drug release from solid dispersions in water-soluble polymers. , 2002, International journal of pharmaceutics.

[16]  S. Hoag,et al.  Influence of various drugs on the glass transition temperature of poly(vinylpyrrolidone): a thermodynamic and spectroscopic investigation. , 2001, International journal of pharmaceutics.

[17]  A. Serajuddin,et al.  Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs. , 1999, Journal of pharmaceutical sciences.

[18]  Sean C. Sweetman,et al.  Martindale: The Complete Drug Reference , 1999 .

[19]  V. Tantishaiyakul,et al.  Properties of solid dispersions of piroxicam in polyvinylpyrrolidone. , 1996, International journal of pharmaceutics.

[20]  Raymond C Rowe,et al.  Handbook of Pharmaceutical Excipients , 1994 .

[21]  O. Corrigan,et al.  Amorphous spray‐dried hydroflumethiazide‐polyvinylpyrrolidone systems: Physicochemical properties , 1984, The Journal of pharmacy and pharmacology.

[22]  M. J. Rosen.  Surfactants and Interfacial Phenomena , 1978 .