Systematic assessment of environmental risk factors for bipolar disorder: an umbrella review of systematic reviews and meta‐analyses

The pathophysiology of bipolar disorder is likely to involve both genetic and environmental risk factors. In our study, we aimed to perform a systematic search of environmental risk factors for BD. In addition, we assessed possible hints of bias in this literature, and identified risk factors supported by high epidemiological credibility.

[1]  J. Ioannidis,et al.  Systematic evaluation of the associations between environmental risk factors and dementia: An umbrella review of systematic reviews and meta-analyses , 2017, Alzheimer's & Dementia.

[2]  A. Carvalho,et al.  The search for neuroimaging and cognitive endophenotypes: A critical systematic review of studies involving unaffected first-degree relatives of individuals with bipolar disorder , 2017, Neuroscience & Biobehavioral Reviews.

[3]  M. Leboyer,et al.  A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model. , 2017, Journal of affective disorders.

[4]  S. Bucci,et al.  Relationship between childhood adversity and bipolar affective disorder: systematic review and meta-analysis , 2016, British Journal of Psychiatry.

[5]  Cheng-Ta Li,et al.  Risk of developing major depression and bipolar disorder among adolescents with atopic diseases: A nationwide longitudinal study in Taiwan. , 2016, Journal of affective disorders.

[6]  J. Soares,et al.  The potential association between obesity and bipolar disorder: A meta-analysis. , 2016, Journal of affective disorders.

[7]  Pao-Yen Lin,et al.  A meta-analysis and systematic review of the comorbidity between irritable bowel syndrome and bipolar disorder , 2016, Medicine.

[8]  R. Post.  Epigenetic basis of sensitization to stress, affective episodes, and stimulants: implications for illness progression and prevention , 2016, Bipolar disorders.

[9]  F. Valenzuela,et al.  Evidences of Polymorphism Associated with Circadian System and Risk of Pathologies: A Review of the Literature , 2016, International journal of endocrinology.

[10]  M. Leboyer,et al.  Toxoplasma gondii exposure may modulate the influence of TLR2 genetic variation on bipolar disorder: a gene–environment interaction study , 2016, International Journal of Bipolar Disorders.

[11]  M. Maes,et al.  Bias in emerging biomarkers for bipolar disorder , 2016, Psychological Medicine.

[12]  R. J. Leo,et al.  Migraine headache and bipolar disorder comorbidity: A systematic review of the literature and clinical implications , 2016, Scandinavian journal of pain.

[13]  A. Danese,et al.  Childhood maltreatment and unfavourable clinical outcomes in bipolar disorder: a systematic review and meta-analysis. , 2016, The lancet. Psychiatry.

[14]  G. Faedda,et al.  The role of environmental exposures as risk factors for bipolar disorder: A systematic review of longitudinal studies. , 2016, Journal of affective disorders.

[15]  Pao-Yen Lin,et al.  Significantly Higher Prevalence Rate of Asthma and Bipolar Disorder Co-Morbidity , 2016, Medicine.

[16]  B. Stubbs.  A random effects meta-analysis investigating the prevalence of bipolar disorder in people with fibromyalgia: An updated analysis. , 2016, Journal of affective disorders.

[17]  M. Berger,et al.  Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis. , 2016, Journal of neurosurgery.

[18]  John P A Ioannidis,et al.  Environmental risk factors and Parkinson's disease: An umbrella review of meta-analyses. , 2016, Parkinsonism & related disorders.

[19]  Ming-Chyi Huang,et al.  Traumatic brain injury and affective disorder: A nationwide cohort study in Taiwan, 2000-2010. , 2016, Journal of affective disorders.

[20]  A. Carvalho,et al.  Exposure to Perinatal Infections and Bipolar Disorder: A Systematic Review. , 2016, Current molecular medicine.

[21]  A. Carvalho,et al.  Bias in Peripheral Depression Biomarkers , 2016, Psychotherapy and Psychosomatics.

[22]  R. McIntyre,et al.  Prevalence of fibromyalgia and co-morbid bipolar disorder: A systematic review and meta-analysis. , 2015, Journal of affective disorders.

[23]  Verinder Sharma,et al.  A Systematic Review of the Association Between Psychiatric Disturbances and Endometriosis. , 2015, Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC.

[24]  R. McIntyre,et al.  Are medical comorbid conditions of bipolar disorder due to immune dysfunction? , 2015, Acta psychiatrica Scandinavica.

[25]  M. Leboyer,et al.  Beyond the association. Toxoplasma gondii in schizophrenia, bipolar disorder, and addiction: systematic review and meta‐analysis , 2015, Acta psychiatrica Scandinavica.

[26]  P. Andersen,et al.  Life expectancy in bipolar disorder , 2015, Bipolar disorders.

[27]  A. Yang,et al.  Risk of Psychiatric Disorders following Irritable Bowel Syndrome: A Nationwide Population-Based Cohort Study , 2015, PloS one.

[28]  P. Andersen,et al.  Causes of decreased life expectancy over the life span in bipolar disorder. , 2015, Journal of affective disorders.

[29]  P. Sienaert,et al.  Prevalence and predictors of type 2 diabetes mellitus in people with bipolar disorder: a systematic review and meta-analysis. , 2015, The Journal of clinical psychiatry.

[30]  K. Blennow,et al.  Monocyte and microglial activation in patients with mood-stabilized bipolar disorder. , 2015, Journal of psychiatry & neuroscience : JPN.

[31]  N. D. de Wit,et al.  Irritable bowel syndrome: an integrated explanatory model for clinical practice , 2015, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[32]  R. McIntyre,et al.  Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders , 2015, Neuroscience & Biobehavioral Reviews.

[33]  J. Ioannidis,et al.  Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses , 2015, The Lancet Neurology.

[34]  P. Lichtenstein,et al.  Bipolar disorder and its relation to major psychiatric disorders: a family‐based study in the Swedish population , 2015, Bipolar disorders.

[35]  E. Bora.  Developmental trajectory of cognitive impairment in bipolar disorder: Comparison with schizophrenia , 2015, European Neuropsychopharmacology.

[36]  Jeffrey A. Cohen,et al.  The incidence and prevalence of psychiatric disorders in multiple sclerosis: A systematic review , 2015, Multiple sclerosis.

[37]  S. Mccarroll,et al.  Characterization of Bipolar Disorder Patient-Specific Induced Pluripotent Stem Cells from a Family Reveals Neurodevelopmental and mRNA Expression Abnormalities , 2014, Molecular Psychiatry.

[38]  A. Erfurth,et al.  Bipolar disorder in adults with Asperger׳s Syndrome: a systematic review. , 2014, Journal of affective disorders.

[39]  N. Ryan,et al.  Longitudinal trajectories and associated baseline predictors in youths with bipolar spectrum disorders. , 2014, The American journal of psychiatry.

[40]  P. Mortensen,et al.  Head injury as risk factor for psychiatric disorders: a nationwide register-based follow-up study of 113,906 persons with head injury. , 2014, The American journal of psychiatry.

[41]  C. Arango,et al.  Differential neurodevelopmental trajectories in patients with early-onset bipolar and schizophrenia disorders. , 2014, Schizophrenia bulletin.

[42]  Rudolf Uher,et al.  Gene–Environment Interactions in Severe Mental Illness , 2014, Front. Psychiatry.

[43]  A. Carvalho,et al.  Obesity and Bipolar Disorder: Synergistic Neurotoxic Effects? , 2013, Advances in Therapy.

[44]  J. Ioannidis.  Clarifications on the application and interpretation of the test for excess significance and its extensions , 2013 .

[45]  M. Leboyer,et al.  Trouble bipolaire à début précoce: Validation par les études de mélange et les biomarqueurs , 2013 .

[46]  P. Sienaert,et al.  Metabolic syndrome and metabolic abnormalities in bipolar disorder: a meta-analysis of prevalence rates and moderators. , 2013, The American journal of psychiatry.

[47]  D. Kupfer,et al.  Can bipolar disorder be viewed as a multi-system inflammatory disease? , 2012, Journal of affective disorders.

[48]  P. Boksa,et al.  Prenatal and postnatal animal models of immune activation: Relevance to a range of neurodevelopmental disorders , 2012, Developmental neurobiology.

[49]  Chiara Nosarti,et al.  Preterm birth and psychiatric disorders in young adult life. , 2012, Archives of general psychiatry.

[50]  T. Dinan,et al.  Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome? , 2011, Brain, Behavior, and Immunity.

[51]  P. Visscher,et al.  Estimating missing heritability for disease from genome-wide association studies. , 2011, American journal of human genetics.

[52]  R. Kessler,et al.  Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. , 2011, Archives of general psychiatry.

[53]  K. Kendler,et al.  Psychiatric ‘diseases’ versus behavioral disorders and degree of genetic influence , 2010, Psychological Medicine.

[54]  Jeremy Grimshaw,et al.  AMSTAR is a reliable and valid measurement tool to assess the methodological quality of systematic reviews. , 2009, Journal of clinical epidemiology.

[55]  David J Spiegelhalter,et al.  A re-evaluation of random-effects meta-analysis , 2009, Journal of the Royal Statistical Society. Series A,.

[56]  M. Keshavan,et al.  Neurodevelopmental basis of bipolar disorder: A critical appraisal , 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[57]  Keith O'Rourke,et al.  Introduction: Rationale, Potentials, and Promise of Systematic Reviews , 2008 .

[58]  Nikolaos A Patsopoulos,et al.  Uncertainty in heterogeneity estimates in meta-analyses , 2007, BMJ : British Medical Journal.

[59]  J. Ioannidis,et al.  An exploratory test for an excess of significant findings , 2007, Clinical trials.

[60]  David Moher,et al.  Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews , 2007, BMC medical research methodology.

[61]  P. Mortensen,et al.  Indicators of fetal growth and bipolar disorder: a Danish national register-based study , 2006, Psychological Medicine.

[62]  Urs Meyer,et al.  Immunological stress at the maternal–foetal interface: A link between neurodevelopment and adult psychopathology , 2006, Brain, Behavior, and Immunity.

[63]  R. Murray,et al.  Exposure to obstetric complications and subsequent development of bipolar disorder , 2006, British Journal of Psychiatry.

[64]  Lei Wang,et al.  Three options for citation tracking: Google Scholar, Scopus and Web of Science , 2006, Biomedical digital libraries.

[65]  P. Mortensen,et al.  Risk factors in relation to an emergence of bipolar disorder: a systematic review. , 2003, Bipolar disorders.

[66]  S. Thompson,et al.  Quantifying heterogeneity in a meta‐analysis , 2002, Statistics in medicine.

[67]  J. Ioannidis,et al.  Quantitative Synthesis in Systematic Reviews , 1997, Annals of Internal Medicine.

[68]  G. Smith,et al.  Bias in meta-analysis detected by a simple, graphical test , 1997, BMJ.