Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis.
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W. Busse | E. Bleecker | S. Wenzel | W. Moore | N. Jarjour | S. Peters | D. Meyers | Huashi Li | Xingnan Li | A. Hastie
[1] E. Bleecker,et al. Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects. , 2013, The Journal of allergy and clinical immunology.
[2] Johny Verschakelen,et al. Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial , 2013, Thorax.
[3] E. R. Sutherland,et al. A large subgroup of mild-to-moderate asthma is persistently noneosinophilic. , 2012, American journal of respiratory and critical care medicine.
[4] P. O'Byrne,et al. Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo‐controlled clinical trial , 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[5] Tonya S. King,et al. Cluster Analysis of Obesity and Asthma Phenotypes , 2012, PloS one.
[6] I. Pavord,et al. Stability of inflammatory phenotypes in asthma , 2012, Thorax.
[7] R. Hancox,et al. Asthma phenotypes: Consistency of classification using induced sputum , 2012, Respirology.
[8] Mario Castro,et al. Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. , 2011, The Journal of allergy and clinical immunology.
[9] D. Jarvis,et al. Identifying adult asthma phenotypes using a clustering approach , 2011, European Respiratory Journal.
[10] Jodie L Simpson,et al. Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples. , 2011, The Journal of allergy and clinical immunology.
[11] Tonya S. King,et al. A trial of clarithromycin for the treatment of suboptimally controlled asthma. , 2010, The Journal of allergy and clinical immunology.
[12] P. Paggiaro,et al. Effects of oral prednisone on sputum eosinophils and cytokines in patients with severe refractory asthma. , 2010, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[13] Deborah A Meyers,et al. Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. , 2010, The Journal of allergy and clinical immunology.
[14] C. Lemière,et al. Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: A prospective study using multiple samples. , 2010, The Journal of allergy and clinical immunology.
[15] D. Curran‐Everett,et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. , 2010, American journal of respiratory and critical care medicine.
[16] J. Cowan,et al. Effects of steroid therapy on inflammatory cell subtypes in asthma , 2009, Thorax.
[17] M. Weatherall,et al. Distinct clinical phenotypes of airways disease defined by cluster analysis , 2009, European Respiratory Journal.
[18] E. Kerwin,et al. A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. , 2009, American journal of respiratory and critical care medicine.
[19] D. Denning,et al. Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study. , 2009, American journal of respiratory and critical care medicine.
[20] Mike Thomas,et al. Cluster analysis and clinical asthma phenotypes. , 2008, American journal of respiratory and critical care medicine.
[21] R. Scott,et al. Clarithromycin targets neutrophilic airway inflammation in refractory asthma. , 2008, American journal of respiratory and critical care medicine.
[22] P. J. Barnes,et al. Global strategy for asthma management and prevention: GINA executive summary , 2008, European Respiratory Journal.
[23] Mario Castro,et al. Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines. , 2008, The Journal of allergy and clinical immunology.
[24] D. Curran‐Everett,et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. , 2007, The Journal of allergy and clinical immunology.
[25] E. Israel,et al. Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids. , 2005, The Journal of allergy and clinical immunology.
[26] A. Zwinderman,et al. "Refractory" eosinophilic airway inflammation in severe asthma: effect of parenteral corticosteroids. , 2004, American journal of respiratory and critical care medicine.
[27] I. Pavord,et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial , 2002, The Lancet.
[28] S. Spector,et al. Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. American Thoracic Society. , 2000, American journal of respiratory and critical care medicine.
[29] Third Expert Panel on theDiagnosis,et al. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma , 1997 .
[30] J. H. Ward. Hierarchical Grouping to Optimize an Objective Function , 1963 .
[31] H. Kaiser. The varimax criterion for analytic rotation in factor analysis , 1958 .