Precues enable multiple response preprogramming: evidence from startle.

When one or more response dimensions in a choice reaction time (RT) task are provided beforehand (or precued), RT decreases, indicating that the precued part of a response was prepared in advance. In this study, a startling acoustic stimulus was used to investigate the amount of preprogramming that occurs when part of the response is precued because a startling stimulus has been shown to directly trigger preprogrammed responses. Participants performed wrist flexion/extension movements in a precued one to four choice RT paradigm. A control auditory stimulus (82 dB) or a startling acoustic stimulus (124 dB) accompanied the visual "go" signal on each trial. Although RT latencies were significantly reduced by the startle, many more errors were observed in the startled conditions. Importantly, the errors seen at short RT latencies largely reflected multiple movements to the cued response alternatives, suggesting that multiple responses were preprogrammed.

[1]  D. Glencross,et al.  Some Experimental Evidence For and Against a Parametric Conception of Movement Programming , 1989 .

[2]  D J Sanderson,et al.  Startle response of human neck muscles sculpted by readiness to perform ballistic head movements , 2001, The Journal of physiology.

[3]  F. Vidal,et al.  Programming response duration in a precueing reaction time paradigm. , 1991, Journal of motor behavior.

[4]  Franck Vidal,et al.  Programming the duration of a motor sequence: role of the primary and supplementary motor areas in man , 2004, Experimental Brain Research.

[5]  Steven W. Keele,et al.  Movement control in skilled motor performance. , 1968 .

[6]  J. Kelso,et al.  Are movements prepared in parts? Not under compatible (naturalized) conditions. , 1980, Journal of experimental psychology. General.

[7]  Comparison of peripheral Ia and corticomotoneuronal composite EPSPs in human motoneurons. , 1996, Electroencephalography and clinical neurophysiology.

[8]  W A MacKay,et al.  CNV, stretch reflex and reaction time correlates of preparation for movement direction and force. , 1990, Electroencephalography and clinical neurophysiology.

[9]  I. Jentzsch,et al.  Beneficial effects of ambiguous precues: parallel motor preparation or reduced premotoric processing time? , 2004, Psychophysiology.

[10]  J C Rothwell,et al.  Role of brainstem–spinal projections in voluntary movement , 2002, Movement disorders : official journal of the Movement Disorder Society.

[11]  J Valls-Solé,et al.  Habituation of the auditory startle reaction is reduced during preparation for execution of a motor task in normal human subjects , 1997, Brain Research.

[12]  J Stahl,et al.  Preparation of response force and movement direction: onset effects on the lateralized readiness potential. , 2000, Psychophysiology.

[13]  I. Jentzsch,et al.  Neural correlates of advance movement preparation: a dipole source analysis approach. , 2001, Brain research. Cognitive brain research.

[14]  T G Reeve,et al.  Evaluation of compatibility effects in the precuing of arm and direction parameters. , 1990, Research quarterly for exercise and sport.

[15]  C M Moore,et al.  Bisecting RT with lateralized readiness potentials: precue effects of LRP onset. , 1995, Acta psychologica.

[16]  J. Valls-Solé,et al.  Reaction time and acoustic startle in normal human subjects , 1995, Neuroscience Letters.

[17]  J. Rothwell,et al.  Techniques and mechanisms of action of transcranial stimulation of the human motor cortex , 1997, Journal of Neuroscience Methods.

[18]  M. Desmurget,et al.  An ‘automatic pilot’ for the hand in human posterior parietal cortex: toward reinterpreting optic ataxia , 2000, Nature Neuroscience.

[19]  B. Cuthbert,et al.  Committee report: Guidelines for human startle eyeblink electromyographic studies. , 2005, Psychophysiology.

[20]  D L Kohfeld,et al.  Effects of the intensity of auditory and visual ready signals on simple reaction time. , 1969, Journal of experimental psychology.

[21]  W. Sommer,et al.  Partial advance information and response preparation: inferences from the lateralized readiness potential. , 1996, Journal of experimental psychology. General.

[22]  J. Valls-Solé,et al.  A startle speeds up the execution of externally guided saccades , 2007, Experimental Brain Research.

[23]  Otmar Bock,et al.  The mechanisms of movement preparation: a precuing study , 2000, Behavioural Brain Research.

[24]  Borís Burle,et al.  Partial advance information, number of alternatives, and motor processes: an electromyographic study. , 2002, Acta psychologica.

[25]  D. Pélisson,et al.  From Eye to Hand: Planning Goal-directed Movements , 1998, Neuroscience & Biobehavioral Reviews.

[26]  I. Jentzsch,et al.  Distinguishing neural sources of movement preparation and execution An electrophysiological analysis , 2002, Biological Psychology.

[27]  Michael Davis The Mammalian Startle Response , 1984 .

[28]  J. Rothwell,et al.  Patterned ballistic movements triggered by a startle in healthy humans , 1999, The Journal of physiology.

[29]  Rolf Ulrich,et al.  Preparing for Action: Inferences from CNV and LRP , 2004 .

[30]  W. E. Hick Quarterly Journal of Experimental Psychology , 1948, Nature.

[31]  Anthony N. Carlsen,et al.  Altered triggering of a prepared movement by a startling stimulus. , 2003, Journal of neurophysiology.

[32]  Paul W. Frankland,et al.  The acoustic startle reflex: neurons and connections , 1995, Brain Research Reviews.

[33]  Stuart T Klapp,et al.  Reaction Time Analysis of Two Types of Motor Preparation for Speech Articulation: Action as a Sequence of Chunks , 2003, Journal of motor behavior.

[34]  D. Rosenbaum Human movement initiation: specification of arm, direction, and extent. , 1980, Journal of experimental psychology. General.

[35]  Adam G. Davidson,et al.  Movement-related and preparatory activity in the reticulospinal system of the monkey , 2004, Experimental Brain Research.

[36]  M. Koch,et al.  The neurobiology of startle , 1999, Progress in Neurobiology.

[37]  C. MacKinnon,et al.  Preparation of anticipatory postural adjustments prior to stepping. , 2007, Journal of neurophysiology.

[38]  Romeo Chua,et al.  Startle response is dishabituated during a reaction time task , 2003, Experimental Brain Research.

[39]  J S Buchwald,et al.  Midlatency auditory evoked responses: differential recovery cycle characteristics. , 1986, Electroencephalography and clinical neurophysiology.

[40]  Ian M Franks,et al.  Prepared Movements Are Elicited Early by Startle , 2004, Journal of motor behavior.

[41]  G A Frekany,et al.  Planning and preparing expected and unexpected movements: reexamining the relationships of arm, direction, and extent of movement. , 1985, Journal of motor behavior.

[42]  H N Zelaznik,et al.  Reaction time methods in the study of motor programming: the precuing of hand, digit, and duration. , 1985, Journal of motor behavior.

[43]  Anthony N. Carlsen,et al.  Can prepared responses be stored subcortically? , 2004, Experimental Brain Research.

[44]  A. Osman,et al.  Temporal organization of covert motor processes during response selection and preparation , 2003, Biological Psychology.

[45]  Trevor Drew,et al.  Independent and convergent signals from the pontomedullary reticular formation contribute to the control of posture and movement during reaching in the cat. , 2004, Journal of neurophysiology.

[46]  Romeo Chua,et al.  Startle produces early response latencies that are distinct from stimulus intensity effects , 2006, Experimental Brain Research.

[47]  J C Rothwell,et al.  New observations on the normal auditory startle reflex in man. , 1991, Brain : a journal of neurology.

[48]  F. Vidal,et al.  The "short-long" reaction time effect in duration programming. , 1996, Journal of motor behavior.

[49]  J. Rothwell,et al.  The startle reflex, voluntary movement, and the reticulospinal tract. , 2006, Supplements to Clinical neurophysiology.

[50]  Anthony N. Carlsen,et al.  Temporal uncertainty does not affect response latencies of movements produced during startle reactions , 2006, Experimental Brain Research.

[51]  B Hyland,et al.  Cortical cell assemblies: a possible mechanism for motor programs. , 1994, Journal of motor behavior.