beta-scission of the N-O bond in alkyl hydroxamate radicals: a fast radical trap.

[reaction--see text ] The rate of the beta-scission of the N-O bond in the alkyl hydroxamate radical is faster than 2 x 10(8) s(-)(1). This reaction may be useful as a radical trap.

[1]  E. Suárez,et al.  SYNTHESIS OF ALDITOLS BY REDUCTIVE RADICAL FRAGMENTATION OF N-PHTHALIMIDO GLYCOSIDES. PREPARATION OF CHIRAL SYNTHETIC INTERMEDIATES , 1999 .

[2]  M. Newcomb,et al.  PICOSECOND RADICAL KINETICS. RATE CONSTANTS FOR RING OPENINGS OF 2-ARYL-SUBSTITUTED CYCLOPROPYLCARBINYL RADICALS , 1999 .

[3]  A. Huang,et al.  Synthesis of Tetrahydrofurans by a Tandem Hydrogen Atom Abstraction/Radical Nucleophilic Displacement Sequence , 1999 .

[4]  K. Kivirikko,et al.  Mechanism-Based Inactivation of the Human Prolyl-4-hydroxylase by 5-Oxaproline-Containing Peptides: Evidence for a Prolyl Radical Intermediate , 1999 .

[5]  M. J. Coon,et al.  Two distinct electrophilic oxidants effects hydroxylation in cytochrome P-450-catalyzed reactions [20] , 1998 .

[6]  A. Clark,et al.  Stereoselectivity in amidyl radical cyclisations. Acyl mode cyclisations , 1998 .

[7]  K. Kivirikko,et al.  Substrate specificity of human prolyl-4-hydroxylase. , 1998, Bioorganic & medicinal chemistry letters.

[8]  Hung‐wen Liu,et al.  Spiropentylacetyl-CoA, A Mechanism-Based Inactivator of Acyl-CoA Dehydrogenases , 1998 .

[9]  N. Castagnoli,et al.  Chemical model studies on the monoamine oxidase-B catalyzed oxidation of 4-substituted 1-methyl-1,2,3,6-tetrahydropyridines. , 1997, Bioorganic & medicinal chemistry.

[10]  R. Silverman.  Radical Ideas about Monoamine Oxidase , 1995 .

[11]  P. Mariano,et al.  Flavin Chemical Models for Monoamine Oxidase Inactivation by Cyclopropylamines, .alpha.-Silylamines, and Hydrazines , 1995 .

[12]  D. Putt,et al.  Cytochrome P450-catalyzed hydroxylation of hydrocarbons: kinetic deuterium isotope effects for the hydroxylation of an ultrafast radical clock. , 1994, Biochemistry.

[13]  R. Silverman,et al.  Evidence against a Nucleophilic Mechanism for Monoamine Oxidase-Catalyzed Amine Oxidation , 1994 .

[14]  S. Zard,et al.  Iminyl radicals: Part III. Further synthetically useful sources of iminyl radicals. , 1994 .

[15]  C. Townsend,et al.  Synthesis and reaction of potential alternate substrates and mechanism-based inhibitors of clavaminate synthase. , 1993, Journal of natural products.

[16]  M. Lai,et al.  Inactivation of medium-chain acyl-CoA dehydrogenase by a metabolite of hypoglycin: characterization of the major turnover product and evidence suggesting an alternative flavin modification pathway , 1993 .

[17]  Stephen J. Lippard,et al.  Radical clock substrate probes and kinetic isotope effect studies of the hydroxylation of hydrocarbons by methane monooxygenase , 1993 .

[18]  M. Lai,et al.  New evidence supporting a radical mechanism of the inactivation of general acyl-CoA dehydrogenase by a metabolite of hypoglycin , 1992 .

[19]  S. Zard,et al.  A new and synthetically useful source of iminyl radicals. , 1992 .

[20]  V. Bowry,et al.  A radical clock investigation of microsomal cytochrome P-450 hydroxylation of hydrocarbons. Rate of oxygen rebound , 1991 .

[21]  C. Schofield,et al.  Studies on the mechanism of deacetoxy–deacetylcephalosporin C synthase using cyclopropyl substituted cephalosporin probes , 1991 .

[22]  C. Suckling.  The Cyclopropyl Group in Studies of Enzyme Mechanism and Inhibition , 1988 .

[23]  J. Baldwin,et al.  Use of the cyclopropylcarbinyl test to detect a radical-like intermediate in penicillin biosynthesis , 1987 .

[24]  J. Walton,et al.  The influence of α-trialkylsilyloxy groups on the rate of ring opening of cyclopropylmethyl radicals , 1983 .