Development of a cellular assay as a personalized model for testing chronic wound therapeutics.
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T. Luger | A. Stuetz | G. Restivo | J. Holzer-Geissler | B. Wolff-Winiski | J. Umlauft | Carina Borst | T. Stockinger | N. Schoefmann | W. Weninger | Matthias Schmuth | Klemens Rappersberger | Sebastian P. Nischwitz | Wolfram Hoetzenecker | Lars E. French | L. Kamolz | Petra Doerfler | Gabriela Cabral | W. Bauer | Martin C. Berli | Barbara Binder | Sander M Botter | Tobias Goerge | J¨urg Hafner | D. Hartmann | Annette Høgh | Katrin Kofler | Michael Popovits | Justin G. Schlager | Georg Stingl | Anke Stroelin
[1] J. McDaniel,et al. Methods for sampling wound fluid from venous leg ulcers for molecular analyses: A scoping review , 2023, International wound journal.
[2] Xin Ma,et al. Metabolism‐related biomarkers, molecular classification, and immune infiltration in diabetic ulcers with validation , 2023, International wound journal.
[3] D. Mooney,et al. Breakthrough treatments for accelerated wound healing , 2023, Science advances.
[4] L. Giacomelli,et al. Researching the level of agreement among experts on terms used to describe wounds: An international study , 2023, International wound journal.
[5] D. Kerob,et al. Wound healing and microbiome, an unexpected relationship , 2023, Journal of the European Academy of Dermatology and Venereology : JEADV.
[6] Winnie Ntow-Boahene,et al. The importance of inflammation control for the treatment of chronic diabetic wounds , 2022, International wound journal.
[7] K. Glass,et al. Transcriptional changes in human palate and skin healing , 2022, bioRxiv.
[8] D. Margolis,et al. Chronic wounds , 2022, Nature Reviews Disease Primers.
[9] J. Thyssen,et al. Cytokines and Venous Leg Ulcer Healing—A Systematic Review , 2022, International journal of molecular sciences.
[10] M. Ågren,et al. Biomarkers of Skin Graft Healing in Venous Leg Ulcers , 2022, Acta dermato-venereologica.
[11] R. Kirsner,et al. Chronic wounds: Treatment consensus , 2022, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[12] J. Rembe,et al. Impact of the chronic wound microenvironment and marine omega‐3 fatty acids on skin cell regeneration processes , 2021, Experimental dermatology.
[13] K. Harding,et al. Wound healing: potential therapeutic options , 2021, The British journal of dermatology.
[14] Q. Deng,et al. Single-cell analysis reveals MHCII expressing keratinocytes in pressure ulcers with worse healing outcomes. , 2021, The Journal of investigative dermatology.
[15] R. Kirsner,et al. Advanced Wound Diagnostics: Towards Transforming Wound Care into Precision Medicine. , 2021, Advances in wound care.
[16] M. Carter,et al. Bacterial protease activity as a biomarker to assess the risk of non‐healing in chronic wounds: Results from a multicentre randomised controlled clinical trial , 2021, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[17] Y. Chai,et al. IL-1β Impaired Diabetic Wound Healing by Regulating MMP-2 and MMP-9 through the p38 Pathway , 2021, Mediators of inflammation.
[18] J. Dengjel,et al. Increased abundance of Cbl E3 ligases alters PDGFR signaling in recessive dystrophic epidermolysis bullosa , 2021, bioRxiv.
[19] Mikaël M. Martino,et al. Restoration of the healing microenvironment in diabetic wounds with matrix-binding IL-1 receptor antagonist , 2021, Communications biology.
[20] M. Bhasin,et al. Single cell transcriptomic landscape of diabetic foot ulcers , 2021, Nature Communications.
[21] Kathleen M. Jagodnik,et al. Gene Set Knowledge Discovery with Enrichr , 2021, Current protocols.
[22] R. Kirsner,et al. Assessing the Need for Negative Pressure Wound Therapy Utilization Guidelines: An Overview of the Challenges With Providing Optimal Care. , 2020, Wounds : a compendium of clinical research and practice.
[23] O. Sköldenberg,et al. Endoplasmic reticulum stress in human chronic wound healing: Rescue by 4‐phenylbutyrate , 2020, International wound journal.
[24] L. Gould,et al. Protease-Resistant Growth Factor Formulations for the Healing of Chronic Wounds. , 2020, Advances in wound care.
[25] M. Hardman,et al. Wound healing: cellular mechanisms and pathological outcomes , 2020, Open Biology.
[26] Deshka S. Foster,et al. Characterization of Diabetic and Non-Diabetic Foot Ulcers Using Single-Cell RNA-Sequencing , 2020, Micromachines.
[27] Radhika S. Khetani,et al. Integrated Skin Transcriptomics and Serum Multiplex Assays Reveal Novel Mechanisms of Wound Healing in Diabetic Foot Ulcers , 2020, Diabetes.
[28] C. Hetz,et al. Mechanisms, regulation and functions of the unfolded protein response , 2020, Nature Reviews Molecular Cell Biology.
[29] A. Seyhan. Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles , 2019, Translational Medicine Communications.
[30] D. Sharma,et al. Vacuum assisted closure (VAC)/negative pressure wound therapy (NPWT) for difficult wounds: A review. , 2019, Journal of clinical orthopaedics and trauma.
[31] V. Velebný,et al. Dual role of iodine, silver, chlorhexidine and octenidine as antimicrobial and antiprotease agents , 2019, PloS one.
[32] G. Gurtner,et al. Wound Healing: A Cellular Perspective. , 2019, Physiological reviews.
[33] S. Shi,et al. Local Administration of Interleukin-1 Receptor Antagonist Improves Diabetic Wound Healing , 2018, Annals of plastic surgery.
[34] R. Trevethan,et al. Sensitivity, Specificity, and Predictive Values: Foundations, Pliabilities, and Pitfalls in Research and Practice , 2017, Front. Public Health.
[35] D. Armstrong,et al. Diabetic Foot Ulcers and Their Recurrence. , 2017, The New England journal of medicine.
[36] K. Kirker,et al. In vitro studies evaluating the effects of biofilms on wound‐healing cells: a review , 2017, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[37] P. Vowden,et al. EWMA Document: Negative Pressure Wound Therapy. , 2017, Journal of wound care.
[38] A. Kramer,et al. Distinct cytokine and chemokine patterns in chronic diabetic ulcers and acute wounds , 2017, Experimental dermatology.
[39] K. Harding,et al. Estimating the costs associated with the management of patients with chronic wounds using linked routine data , 2016, International wound journal.
[40] J. Davidson,et al. Wound samples: moving towards a standardised method of collection and analysis , 2016, International wound journal.
[41] O. Stojadinović,et al. Biology and Biomarkers for Wound Healing , 2016, Plastic and reconstructive surgery.
[42] M. Carter,et al. Defining a new diagnostic assessment parameter for wound care: Elevated protease activity, an indicator of nonhealing, for targeted protease‐modulating treatment , 2016, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[43] R. Kirsner,et al. What's new: Management of venous leg ulcers: Approach to venous leg ulcers. , 2016, Journal of the American Academy of Dermatology.
[44] L. Stein,et al. The Reactome pathway Knowledgebase , 2015, Nucleic Acids Res..
[45] E. Neugebauer,et al. Adipose‐derived stem cells and keratinocytes in a chronic wound cell culture model: the role of hydroxyectoine , 2015, International wound journal.
[46] E. Neugebauer,et al. Acute and chronic wound fluids influence keratinocyte function differently , 2015, International wound journal.
[47] E. O’Toole,et al. Metalloproteinases and Wound Healing. , 2015, Advances in wound care.
[48] E. Neugebauer,et al. Acute and chronic wound fluids inversely influence adipose‐derived stem cell function: molecular insights into impaired wound healing , 2015, International wound journal.
[49] T. Serena. Development of a Novel Technique to Collect Proteases from Chronic Wounds. , 2014, Advances in wound care.
[50] Paul Martin,et al. Wound repair and regeneration: Mechanisms, signaling, and translation , 2014, Science Translational Medicine.
[51] L. Giurato,et al. High Matrix Metalloproteinase Levels Are Associated With Dermal Graft Failure in Diabetic Foot Ulcers , 2014, The international journal of lower extremity wounds.
[52] M. Löffler,et al. Wound Fluid in Diabetic Foot Ulceration , 2013, The international journal of lower extremity wounds.
[53] Nicholas A Richmond,et al. Evidence‐based management of common chronic lower extremity ulcers , 2013, Dermatologic therapy.
[54] D. Pincus,et al. Endoplasmic reticulum stress sensing in the unfolded protein response. , 2013, Cold Spring Harbor perspectives in biology.
[55] Jacqueline Fletcher,et al. Extending the TIME concept: what have we learned in the past 10 years? * , 2012, International wound journal.
[56] T. Joos,et al. Superficial Wound Swabbing , 2012, Diabetes Care.
[57] S. Zehtabchi,et al. Silver sulfadiazine for the treatment of partial-thickness burns and venous stasis ulcers. , 2012, Journal of the American Academy of Dermatology.
[58] O. Schilling,et al. Biological role of matrix metalloproteinases: a critical balance , 2010, European Respiratory Journal.
[59] Jay W Fox,et al. Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds. , 2010, Journal of proteome research.
[60] K. Harding,et al. Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. , 2010, Journal of dermatological science.
[61] R. Snyder,et al. A post-hoc analysis of reduction in diabetic foot ulcer size at 4 weeks as a predictor of healing by 12 weeks. , 2010, Ostomy/wound management.
[62] T. K. Hunt,et al. Human skin wounds: A major and snowballing threat to public health and the economy , 2009, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[63] L. Gould,et al. Proteolytic activity in wound fluids and tissues derived from chronic venous leg ulcers , 2009, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[64] J. Tarlton,et al. The relationship between cytokine concentrations and wound healing in chronic venous ulceration. , 2008, Journal of vascular surgery.
[65] W. Alkema,et al. BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams , 2008, BMC Genomics.
[66] E. Maltezos,et al. Becaplermin gel in the treatment of diabetic neuropathic foot ulcers , 2008, Clinical interventions in aging.
[67] E. Elster,et al. Correlation of procalcitonin and cytokine expression with dehiscence of wartime extremity wounds. , 2008, The Journal of bone and joint surgery. American volume.
[68] T. Phillips,et al. Chronic wound fluid suppresses proliferation of dermal fibroblasts through a Ras-mediated signaling pathway. , 2005, The Journal of investigative dermatology.
[69] J. Raffetto,et al. Proliferative Capacity of Venous Ulcer Wound Fibroblasts in the Presence of Platelet-Derived Growth Factor , 2004, Vascular and endovascular surgery.
[70] J. Giurini,et al. Percent change in wound area of diabetic foot ulcers over a 4-week period is a robust predictor of complete healing in a 12-week prospective trial. , 2003, Plastic and reconstructive surgery.
[71] U. Mirastschijski,et al. Ectopic localization of matrix metalloproteinase-9 in chronic cutaneous wounds. , 2002, Human pathology.
[72] M. Stacey,et al. Mitogenic activity and cytokine levels in non‐healing and healing chronic leg ulcers , 2001, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[73] F. Gottrup,et al. A new concept of a multidisciplinary wound healing center and a national expert function of wound healing. , 2001, Archives of surgery.
[74] J. Raffetto,et al. Changes in cellular motility and cytoskeletal actin in fibroblasts from patients with chronic venous insufficiency and in neonatal fibroblasts in the presence of chronic wound fluid. , 2001, Journal of vascular surgery.
[75] G. Schultz,et al. Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors , 1999, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[76] J. Raffetto,et al. The proliferative capacity of neonatal skin fibroblasts is reduced after exposure to venous ulcer wound fluid: A potential mechanism for senescence in venous ulcers. , 1999, Journal of vascular surgery.
[77] M. Leverkus,et al. Effect of chronic wound fluid on fibroblasts. , 1998, Journal of wound care.
[78] R. Diegelmann,et al. Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors , 1997, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[79] W. Cunliffe,et al. Cytokine and protease levels in healing and non‐healing chronic venous leg ulcers , 1995, Experimental dermatology.
[80] W. Eaglstein,et al. Inhibition of cell proliferation by chronic wound fluid , 1993, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[81] R. Kirsner,et al. Human wound fluid from acute wounds stimulates fibroblast and endothelial cell growth. , 1991, Journal of the American Academy of Dermatology.
[82] D. Scudiero,et al. New colorimetric cytotoxicity assay for anticancer-drug screening. , 1990, Journal of the National Cancer Institute.
[83] T. Behl,et al. Role of matrix metalloproteinase in wound healing. , 2022, American journal of translational research.
[84] T. Phillips,et al. Early healing rates and wound area measurements are reliable predictors of later complete wound closure , 2008, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[85] D. Armstrong,et al. The role of matrix metalloproteinases in wound healing. , 2002, Journal of the American Podiatric Medical Association.