Diagnosing Alzheimer's disease: A systematic review of economic evaluations

The objective of this study is to systematically review the literature on economic evaluations of interventions for the early diagnosis of Alzheimer's disease (AD) and related disorders and to describe their general and methodological characteristics. We focused on the diagnostic aspects of the decision models to assess the applicability of existing decision models for the evaluation of the recently revised diagnostic research criteria for AD.

[1]  Nick C Fox,et al.  The Diagnosis of Mild Cognitive Impairment due to Alzheimer’s Disease: Recommendations from the National Institute on Aging-Alzheimer’s Association Workgroups on Diagnostic Guidelines for Alzheimer’s Disease , 2011 .

[2]  Raphael Wittenberg,et al.  Clinical and cost effectiveness of services for early diagnosis and intervention in dementia , 2009, International journal of geriatric psychiatry.

[3]  M. Sculpher,et al.  Decision Modelling for Health Economic Evaluation , 2006 .

[4]  Denise C. Park,et al.  Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[5]  Grazyna Adamiak,et al.  Methods for the economic evaluation of health care programmes, 3rd ed , 2006 .

[6]  Khajak J. Ishak,et al.  An economic evaluation of early assessment for Alzheimer’s disease in the United Kingdom , 2012, Alzheimer's & Dementia.

[7]  Ralf Schulze,et al.  The efficacy of diagnostic imaging. , 2012, Dento maxillo facial radiology.

[8]  A. Maes,et al.  Cost‐effectiveness of 18F‐fluorodeoxyglucose positron emission tomography in the assessment of early dementia from a Belgian and European perspective , 2005, European journal of neurology.

[9]  Jeffrey L. Cummings,et al.  Practice parameter: Diagnosis of dementia (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology , 2001 .

[10]  J. Rizzo,et al.  Understanding the medical and nonmedical value of diagnostic testing. , 2010, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[11]  H. D. de Vet,et al.  Criteria list for assessment of methodological quality of economic evaluations: Consensus on Health Economic Criteria , 2005, International Journal of Technology Assessment in Health Care.

[12]  A. Norlund,et al.  Health economic evaluations: How to find them , 2006, International Journal of Technology Assessment in Health Care.

[13]  M. Folstein,et al.  Clinical diagnosis of Alzheimer's disease , 1984, Neurology.

[14]  J. Manthorpe,et al.  Editorial: The hazards of early recognition of dementia: a risk assessment , 2004, Aging & mental health.

[15]  J. Knottnerus,et al.  The Evidence Base of Clinical Diagnosis: Theory and Methods of Diagnostic Research , 2008 .

[16]  David McDaid,et al.  Searching Literature Databases for Health Care Economic Evaluations: How Systematic Can We Afford to Be? , 2002, Medical care.

[17]  S. Golder,et al.  Good Practice Guidelines for Decision-Analytic Modelling in Health Technology Assessment , 2012, PharmacoEconomics.

[18]  Denis Getsios,et al.  Cost Effectiveness of Donepezil in the Treatment of Mild to Moderate Alzheimer’s Disease , 2012, PharmacoEconomics.

[19]  Bob Woods,et al.  Nonpharmacological Therapies in Alzheimer’s Disease: A Systematic Review of Efficacy , 2010, Dementia and Geriatric Cognitive Disorders.

[20]  Andy Stergachis,et al.  The Role of Cost—Consequence Analysis in Healthcare Decision—Making , 1998, PharmacoEconomics.

[21]  A. Wimo,et al.  The global prevalence of dementia: A systematic review and metaanalysis , 2013, Alzheimer's & Dementia.

[22]  C. Green.  Modelling disease progression in Alzheimer's disease: a review of modelling methods used for cost-effectiveness analysis. , 2007, PharmacoEconomics.

[23]  Joshua T. Cohen,et al.  Willingness-to-pay for predictive tests with no immediate treatment implications: a survey of US residents. , 2012, Health economics.

[24]  G. Small,et al.  Added clinical benefit of incorporating 2-deoxy-2-[18F]fluoro-D-glucose with positron emission tomography into the clinical evaluation of patients with cognitive impairment. , 2002, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

[25]  G. Gazelle,et al.  Cost-effectiveness of PET in the diagnosis of Alzheimer disease. , 2003, Radiology.

[26]  Johan L Severens,et al.  Modeling complex treatment strategies: construction and validation of a discrete event simulation model for glaucoma. , 2010, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[27]  G. Gazelle,et al.  Cost-effectiveness of functional imaging tests in the diagnosis of Alzheimer disease. , 2000, Radiology.

[28]  M J Buxton,et al.  Modelling in economic evaluation: an unavoidable fact of life. , 1997, Health economics.

[29]  Kirsten McCaffery,et al.  Additional Patient Outcomes and Pathways in Evaluations of Testing , 2009, Medical decision making : an international journal of the Society for Medical Decision Making.

[30]  M. Folstein,et al.  Clinical diagnosis of Alzheimer's disease: Report of the NINCDS—ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease , 2011, Neurology.

[31]  J T O'Brien,et al.  EFNS guidelines for the diagnosis and management of Alzheimer’s disease , 2010, European journal of neurology.

[32]  John Bond,et al.  The worldwide economic impact of dementia 2010 , 2013, Alzheimer's & Dementia.

[33]  H. Brodaty,et al.  ALZHEIMER'S DISEASE INTERNATIONAL , 1997, International journal of geriatric psychiatry.

[34]  M. Drummond,et al.  Health Care Technology: Effectiveness, Efficiency and Public Policy@@@Methods for the Economic Evaluation of Health Care Programmes , 1988 .

[35]  S. Wilson.  Methods for the economic evaluation of health care programmes , 1987 .

[36]  J. Morris,et al.  The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[37]  M. Prince,et al.  World Alzheimer Report 2013 , 2014 .

[38]  M. Lubin,et al.  Cost-Effectiveness of Computerized Tomography and Magnetic Resonance Imaging in Dementia , 1985, Medical decision making : an international journal of the Society for Medical Decision Making.

[39]  David L. Weimer,et al.  Early identification and treatment of Alzheimer's disease: Social and fiscal outcomes , 2009, Alzheimer's & Dementia.

[40]  Milton C. Weinstein,et al.  Recent Developments in Decision-Analytic Modelling for Economic Evaluation , 2012, PharmacoEconomics.

[41]  C. Dirksen,et al.  Economic evaluation of an integrated diagnostic approach for psychogeriatric patients: results of a randomized controlled trial. , 2009, Archives of general psychiatry.

[42]  P. Scheltens,et al.  Diagnostic and economic evaluation of new biomarkers for Alzheimer’s disease: the research protocol of a prospective cohort study , 2012, BMC Neurology.

[43]  D. Ramaekers,et al.  The evaluation of diagnostic tests: evidence on technical and diagnostic accuracy, impact on patient outcome and cost-effectiveness is needed. , 2007, Journal of clinical epidemiology.

[44]  B. Miller,et al.  CME Practice parameter : Diagnosis of dementia ( an evidence-based review ) Report of the Quality Standards Subcommittee of the American Academy of Neurology , 2001 .

[45]  Vijaya L. Melnick,et al.  Alzheimer’s Dementia , 1985, Contemporary Issues in Biomedicine, Ethics, and Society.

[46]  Jill Manthorpe,et al.  Sooner or later? Issues in the early diagnosis of dementia in general practice: a qualitative study. , 2003, Family practice.

[47]  M Sculpher,et al.  Review of guidelines for good practice in decision-analytic modelling in health technology assessment. , 2004, Health technology assessment.

[48]  G. Rinkel,et al.  Decision analysis to complete diagnostic research by closing the gap between test characteristics and cost-effectiveness. , 2009, Journal of clinical epidemiology.

[49]  M. Albert,et al.  Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[50]  Joshua T. Cohen,et al.  Decision analytic models for Alzheimer's disease: State of the art and future directions , 2008, Alzheimer's & Dementia.