Routes of chloroform exposure and body burden from showering with chlorinated tap water.

While there is an awareness of the need to quantify inhalation exposure from showers, the potential for dermal exposure to organic contaminants in showers has not been appreciated or explored. To establish routes of environmental exposure from showers, comparisons of the concentration of chloroform in exhaled breath after a normal shower with municipal tap water were made with those after an inhalation-only exposure. The postexposure chloroform breath concentrations ranged from 6.0-21 micrograms/m3 for normal showers and 2.4 to 10 micrograms/m3 for inhalation-only exposure, while the pre-exposure concentrations were all less than the minimum detection limit of 0.86 micrograms/m3. According to an F-test, the difference between the normal shower and the inhalation-only exposures was considered significant at a probability of p = 0.0001. Based on the difference, the mean internal dose due to dermal exposure was found to be approximately equal to that due to the inhalation exposure. The effect of the showering activities on the concentration of chloroform shower air was examined by comparing air concentrations during a normal shower with the air concentrations obtained when the shower was unoccupied. The F-test showed that there is no significant difference between the two sets of data.

[1]  M. Wolff Evidence for existence in human tissues of monomers for plastics and rubber manufacture. , 1976, Environmental health perspectives.

[2]  D. Hattis,et al.  The Role of Skin Absorption as a Route of Exposure to Volatile Organic Compounds in Household Tap Water: A Simulated Kinetic Approach , 1989 .

[3]  T. A. Bellar,et al.  Determining volatile organics at microgram-per-litre levels by gas chromatography , 1974 .

[4]  Richard D. Stewart,et al.  ABSORPTION OF CARBON TETRACHLORIDE, TRICHLOROETHYLENE, TETRACHLOROETHYLENE, METHYLENE CHLORIDE, AND 1,1,1-TRICHLOROETHANE THROUGH THE HUMAN SKIN. , 1964 .

[5]  J. Wahlberg Percutaneous toxicity of solvents. A comparative investigation in the guinea pig with benzene, toluene and 1,1,2-trichloroethane. , 1976, Annals of Occupational Hygiene.

[6]  Thomas E. McKone,et al.  Human exposure to volatile organic compounds in household tap water: the indoor inhalation pathway , 1987 .

[7]  J. B. Andelman Inhalation exposure in the home to volatile organic contaminants of drinking water. , 1985, The Science of the total environment.

[8]  R. Scheuplein,et al.  Permeability of the Skin , 1971 .

[9]  H. Maibach,et al.  Human Skin Binding and Absorption of Contaminants from Ground and Surface Water During Swimming and Bathing , 1989 .

[10]  E M Waters,et al.  Trichloroethylene. I. An overview. , 1977, Journal of toxicology and environmental health.

[11]  H. Härkönen Styrene, its experimental and clinical toxicology. A review. , 1978, Scandinavian Journal of Work, Environment and Health.

[12]  J. B. Andelman Human exposures to volatile halogenated organic chemicals in indoor and outdoor air. , 1985, Environmental health perspectives.