Receptors of anthrax toxin and cell entry.

[1]  J. Gruenberg,et al.  Molecular assemblies and membrane domains in multivesicular endosome dynamics. , 2009, Experimental cell research.

[2]  Harald Stenmark,et al.  The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins , 2009, Nature.

[3]  M. Manchester,et al.  Anti-toxin antibodies in prophylaxis and treatment of inhalation anthrax. , 2009, Future microbiology.

[4]  Jack F. Eichler,et al.  Monitoring anthrax toxin receptor dissociation from the protective antigen by NMR , 2008, Protein science : a publication of the Protein Society.

[5]  John A. Young,et al.  Efficient Neutralization of Antibody-Resistant Forms of Anthrax Toxin by a Soluble Receptor Decoy Inhibitor , 2008, Antimicrobial Agents and Chemotherapy.

[6]  G. Davidson,et al.  Functional interactions between anthrax toxin receptors and the WNT signalling protein LRP6 , 2008, Cellular microbiology.

[7]  J. Mogridge,et al.  The Cytoplasmic Domain of Anthrax Toxin Receptor 1 Affects Binding of the Protective Antigen , 2008, Infection and Immunity.

[8]  S. Leppla,et al.  Role of N-Terminal Amino Acids in the Potency of Anthrax Lethal Factor , 2008, PloS one.

[9]  A Dual-Purpose Protein Ligand for Effective Therapy and Sensitive Diagnosis of Anthrax , 2008, The protein journal.

[10]  M. Herlyn,et al.  Cytotoxicity of the matrix metalloproteinase–activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells , 2008, Molecular Cancer Therapeutics.

[11]  John A. Young,et al.  Evidence against a Human Cell-Specific Role for LRP6 in Anthrax Toxin Entry , 2008, PloS one.

[12]  S. Leppla,et al.  Potent inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin: Implications for broad anti-tumor efficacy , 2008, Cell cycle.

[13]  H. Inoue,et al.  Arf GAPs and Their Interacting Proteins , 2007, Traffic.

[14]  S. Leppla,et al.  Characterization of the interaction between anthrax toxin and its cellular receptors , 2007, Cellular microbiology.

[15]  R. Liddington,et al.  Selection of Anthrax Toxin Protective Antigen Variants That Discriminate between the Cellular Receptors TEM8 and CMG2 and Achieve Targeting of Tumor Cells* , 2007, Journal of Biological Chemistry.

[16]  John A. Young,et al.  Anthrax Toxin Receptor 2 Determinants that Dictate the pH Threshold of Toxin Pore Formation , 2007, PloS one.

[17]  J. Resau,et al.  LRP5 and LRP6 Are Not Required for Protective Antigen–Mediated Internalization or Lethality of Anthrax Lethal Toxin , 2007, PLoS pathogens.

[18]  John A. Young,et al.  Divalent Metal Ion Coordination by Residue T118 of Anthrax Toxin Receptor 2 Is Not Essential for Protective Antigen Binding , 2006, PloS one.

[19]  M. Zaccolo,et al.  Cell entry and cAMP imaging of anthrax edema toxin , 2006, The EMBO journal.

[20]  A. Ridley.  Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. , 2006, Trends in cell biology.

[21]  John A. Young,et al.  Anthrax Toxin Receptor 2–Dependent Lethal Toxin Killing In Vivo , 2006, PLoS pathogens.

[22]  R. Kane,et al.  Polyvalent inhibitors of anthrax toxin that target host receptors , 2006, Proceedings of the National Academy of Sciences.

[23]  V. Faundez,et al.  Anthrax Toxin Receptor 1/Tumor Endothelium Marker 8 Mediates Cell Spreading by Coupling Extracellular Ligands to the Actin Cytoskeleton* , 2006, Journal of Biological Chemistry.

[24]  Benhur Lee,et al.  Anthrax oedema toxin induces anthrax toxin receptor expression in monocyte‐derived cells , 2006, Molecular microbiology.

[25]  Sanguk Kim,et al.  Self-association of the transmembrane domain of an anthrax toxin receptor. , 2006, Journal of molecular biology.

[26]  P. Hawkins,et al.  ARAP3 is essential for formation of lamellipodia after growth factor stimulation , 2006, Journal of Cell Science.

[27]  S. Leppla,et al.  Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis , 2006, The Journal of cell biology.

[28]  John A. Young,et al.  Whole-cell Voltage Clamp Measurements of Anthrax Toxin Pore Current* , 2005, Journal of Biological Chemistry.

[29]  John A. Young,et al.  A soluble receptor decoy protects rats against anthrax lethal toxin challenge. , 2005, The Journal of infectious diseases.

[30]  John A. Young,et al.  Receptor-specific requirements for anthrax toxin delivery into cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[31]  K. Hotchkiss,et al.  TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen. , 2005, Experimental cell research.

[32]  J. Ezzell,et al.  Purified Bacillus anthracis Lethal Toxin Complex Formed in Vitro and during Infection Exhibits Functional and Biological Activity* , 2005, Journal of Biological Chemistry.

[33]  K. Hotchkiss,et al.  ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection. , 2005, American journal of physiology. Cell physiology.

[34]  Stanley N Cohen,et al.  EST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxin. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[35]  N. E. Hall,et al.  ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner , 2004, Journal of Cell Science.

[36]  W. Jiang,et al.  Upregulation of tumour endothelial marker-8 by interleukin-1β and its impact in IL-1β induced angiogenesis , 2004 .

[37]  S. Harrison,et al.  Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[38]  S. Leppla,et al.  Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway , 2004, The Journal of cell biology.

[39]  Robert C. Liddington,et al.  Crystal structure of a complex between anthrax toxin and its host cell receptor , 2004, Nature.

[40]  Roger L. Williams,et al.  ARAP3 Is a PI3K- and Rap-Regulated GAP for RhoA , 2004, Current Biology.

[41]  P. De Camilli,et al.  CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors. , 2004, Molecular biology of the cell.

[42]  D. Lacy,et al.  Binding Stoichiometry and Kinetics of the Interaction of a Human Anthrax Toxin Receptor, CMG2, with Protective Antigen* , 2004, Journal of Biological Chemistry.

[43]  John A. Young,et al.  Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[44]  S. Leppla,et al.  The roles of anthrax toxin in pathogenesis. , 2004, Current opinion in microbiology.

[45]  K. Kinzler,et al.  TEM8 Interacts with the Cleaved C5 Domain of Collagen α3(VI) , 2004, Cancer Research.

[46]  Xi He,et al.  A mechanism for Wnt coreceptor activation. , 2004, Molecular cell.

[47]  W. Jiang,et al.  Upregulation of tumour endothelial marker-8 by interleukin-1beta and its impact in IL-1beta induced angiogenesis. , 2004, International journal of molecular medicine.

[48]  K. Kinzler,et al.  TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI). , 2004, Cancer research.

[49]  John A. Young,et al.  Binding of Anthrax Toxin to Its Receptor Is Similar to α Integrin-Ligand Interactions* , 2003, Journal of Biological Chemistry.

[50]  John A. Young,et al.  Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[51]  Shihui Liu,et al.  Cell Surface Tumor Endothelium Marker 8 Cytoplasmic Tail-independent Anthrax Toxin Binding, Proteolytic Processing, Oligomer Formation, and Internalization* , 2003, The Journal of Biological Chemistry.

[52]  S. Leppla,et al.  Anthrax toxin triggers endocytosis of its receptor via a lipid raft–mediated clathrin-dependent process , 2003, The Journal of cell biology.

[53]  Kenneth A Bradley,et al.  Anthrax toxin receptor proteins. , 2003, Biochemical pharmacology.

[54]  I. Dikic,et al.  Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[55]  R. Collier,et al.  Stoichiometry of anthrax toxin complexes. , 2002, Biochemistry.

[56]  P. Lipp,et al.  Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. , 2002, Molecular cell.

[57]  John A. Young,et al.  Identification of the cellular receptor for anthrax toxin , 2001, Nature.

[58]  K. Kinzler,et al.  Cell surface tumor endothelial markers are conserved in mice and humans. , 2001, Cancer research.

[59]  S. Maxwell,et al.  Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. , 2001, Journal of cell science.

[60]  H. Bujo.  [The LDL receptor-related protein (LRP)]. , 2001, Nihon rinsho. Japanese journal of clinical medicine.

[61]  William C. Skarnes,et al.  An LDL-receptor-related protein mediates Wnt signalling in mice , 2000, Nature.

[62]  Yoichi Kato,et al.  LDL-receptor-related proteins in Wnt signal transduction , 2000, Nature.

[63]  K. Kinzler,et al.  Genes expressed in human tumor endothelium. , 2000, Science.

[64]  M. Mock,et al.  Anthrax lethal factor cleaves the N‐terminus of MAPKKS and induces tyrosine/threonine phosphorylation of MAPKS in cultured macrophages , 1999, Journal of applied microbiology.

[65]  K D Paull,et al.  Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. , 1998, Science.

[66]  S. Leppla,et al.  Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.