Metabolism of arginine and ornithine in the cow and rabbit mammary tissue.

Amino acid uptake by the bovine mammary gland was determined by arteriovenous difference. Extraction of arginine from the plasma by the lactating bovine mammary gland was in excess of requirements for milk protein synthesis. Ornithine and citrulline also were extracted by the gland but are not in milk protein. Incubations of slices of lactating mammary tissue from cows and rabbits indicate that nonessential amino acids, especially proline and glutamate, are the major end products of arginine and ornithine metabolism in the lactating mammary gland.

[1]  R. Bickerstaffe,et al.  The metabolism of glucose, acetate, lipids and amino acids in lactating dairy cows , 1974, The Journal of Agricultural Science.

[2]  J. H. Clark,et al.  Effect of abomasal infusion of sodium caseinate on milk yield, nitrogen utilization and amino acid nutrition of the dairy cow. , 1974, The Journal of nutrition.

[3]  W. Knox,et al.  Function of arginase in lactating mammary gland. , 1972, The Biochemical journal.

[4]  R. E. Brown,et al.  Pathways of fatty acid synthesis and reducing equivalent generation in mammary gland of rat, sow, and cow. , 1970, Archives of biochemistry and biophysics.

[5]  O. Greengard,et al.  Developmental formation and distribution of arginase in rat tissues. , 1970, Archives of biochemistry and biophysics.

[6]  G. H. Smith,et al.  Variations with energy nutrition in the concentrations of amino acids of the blood plasma in the dairy cow , 1969, British Journal of Nutrition.

[7]  C. West,et al.  Mammary metabolism in lactating sows: arteriovenous differences of milk precursors and the mammary metabolism of [14C]glucose and [14C]acetate , 1969, British Journal of Nutrition.

[8]  C. Ramberg,et al.  Mammary blood flow and ketone body metabolism in normal, fasted, and ketotic cows. , 1968, The American journal of physiology.

[9]  R. Verbeke,et al.  Incorporation of DL-[2-14C]ornithine and DL-[5-14C]arginine in milk constituents by the isolated lactating sheep udder. , 1968, The Biochemical journal.

[10]  J. Linzell,et al.  Urea Formation by the Lactating Goat Mammary Gland , 1967, Nature.

[11]  J. Linzell,et al.  A quantitative assessment of the contribution of individual plasma amino acids to the synthesis of milk proteins by the goat mammary gland. , 1966, The Biochemical journal.

[12]  R. Verbeke,et al.  UPTAKE OF FREE PLASMA AMINO ACIDS BY THE LACTATING COW'S UDDER AND AMINO ACID COMPOSITION OF UDDER LYMPH. , 1965, The Biochemical journal.

[13]  R. Schimke.  Adaptive characteristics of urea cycle enzymes in the rat. , 1962, The Journal of biological chemistry.

[14]  D. M. Greenberg.  Carbon Catabolism of Amino Acids , 1961 .

[15]  P. Cohen,et al.  Nitrogen Metabolism of Amino Acids , 1961 .

[16]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[17]  A. Greenbaum,et al.  Changes in the arginase and alkaline phosphatase contents of the mammary gland and liver of the rat during pregnancy, lactation and mammary involution. , 1947, The Biochemical journal.

[18]  C. W. Turner,et al.  THE PRODUCTION OF UREA IN THE MAMMARY GLAND , 1937 .