In this work, we are interested to data exchanges inter-enterprises called business-to-business (B2B) e-commerce. A B2B collaboration is a set of documents exchanges and complex interactions between organizations. Such a long process transaction may be reliable, protected, secure, and requires standardization especially for accomplishing smooth business process. This need for standardization has been recognized and the development of business standards like ebXML can be viewed as a solution. In this paper, we present a framework of an agent-based approach using the ebXML specification for B2B E-commerce. The motivation for using agents in support of e-commerce is to perform dedicated processing on behalf of clients. In addition, the agents' technology can provide a high degree of flexibility by distributing the complex problem on intelligent and cooperative entities called "intelligent agents". Also, the mobility of an agent can allow for a faster time scale of service deployment.
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