CLINICAL EXPERIENCE WITH 6‐MERCAPTOPURINE IN HUMAN NEOPLASIA

This report is concerned with the results obtained from the oral administration of 6-mercaptopurine (6-MP) in 24 adult patients and 1 child with acute leukemia, 5 patients with chronic granulocytic leukemia, 1 patient with chronic lymphocytic leukemia, 2 patients with myeloma, and 9 patients with various types of miscellaneous metastatic cancers. Of the 25 patients with acute leukemia, 10 were lymphocytic, 7 were monocytic, and 8 were granulocytic. Six of the granulocytic leukemias were acute from onset, and 2 represented the acute terminal phase of chronic granulocytic leukemia.