Auto-Segmentation of Pathological Lung Parenchyma Based on Region Growing Method

Lung parenchyma extraction is a precursor to the diagnosis and analysis of lung diseases. In this study, we propose a fully automated lung segmentation method that is able to extract lung parenchyma from both normal and pathological lung. First, we adapt the threshold algorithm to perform image binary, and then utilize the connected domain labeling method to select seed for region growing segmentation method which will be performed next. Then region growing image segmentation method is adopted and a rudimentary lung volume is established. A further refinement is performed to include the areas that might have been missed during the segmentation by an improved convex hull algorithm. We evaluated the accuracy and efficiency of the proposed method on 10 3D-CT scan sets. The results show that the improved convex hull algorithm can repair the concavities of lung contour effectively and the proposed segmentation method can extract the lung parenchyma precisely.

[1]  Sabina Sonia Tangaro,et al.  Automatic Lung Segmentation in CT Images with Accurate Handling of the Hilar Region , 2011, Journal of Digital Imaging.

[2]  Richard C. Pais,et al.  The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): a completed reference database of lung nodules on CT scans. , 2011, Medical physics.

[3]  Roger Zimmermann,et al.  Flickr Circles: Aesthetic Tendency Discovery by Multi-View Regularized Topic Modeling , 2016, IEEE Transactions on Multimedia.

[4]  Michael F. McNitt-Gray,et al.  Method for segmenting chest CT image data using an anatomical model: preliminary results , 1997, IEEE Transactions on Medical Imaging.

[5]  G J Kemerink,et al.  On segmentation of lung parenchyma in quantitative computed tomography of the lung. , 1998, Medical physics.

[6]  Reinhard Beichel,et al.  An approach for reducing the error rate in automated lung segmentation , 2016, Comput. Biol. Medicine.

[7]  N. Otsu A threshold selection method from gray level histograms , 1979 .

[8]  Kai-Sheng Hsieh,et al.  Unsupervised segmentation of lung fields in chest radiographs using multiresolution fractal feature vector and deformable models , 2015, Medical & Biological Engineering & Computing.

[9]  Akinobu Shimizu,et al.  Multi-shape graph cuts with neighbor prior constraints and its application to lung segmentation from a chest CT volume , 2013, Medical Image Anal..

[10]  Robert J. Gillies,et al.  A Robust Approach for Automated Lung Segmentation in Thoracic CT , 2015, 2015 IEEE International Conference on Systems, Man, and Cybernetics.

[11]  O. M. Rijal,et al.  Enhanced automatic lung segmentation using graph cut for Interstitial Lung Disease , 2014, 2014 IEEE Conference on Biomedical Engineering and Sciences (IECBES).

[12]  S. McGuire World Cancer Report 2014. Geneva, Switzerland: World Health Organization, International Agency for Research on Cancer, WHO Press, 2015. , 2016, Advances in nutrition.

[13]  Jayaram K. Udupa,et al.  A Generic Approach to Pathological Lung Segmentation , 2014, IEEE Transactions on Medical Imaging.

[14]  Meng Wang,et al.  Multi-View Object Retrieval via Multi-Scale Topic Models , 2016, IEEE Transactions on Image Processing.

[15]  Yifei Zhang,et al.  A novel approach of lung segmentation on chest CT images using graph cuts , 2015, Neurocomputing.

[16]  Gustavo Carneiro,et al.  Lung segmentation in chest radiographs using distance regularized level set and deep-structured learning and inference , 2015, 2015 IEEE International Conference on Image Processing (ICIP).