MicroRNAs and Inflammatory Bowel Disease

[1]  G. Meister,et al.  Publisher Correction: Regulation of microRNA biogenesis and its crosstalk with other cellular pathways , 2018, Nature Reviews Molecular Cell Biology.

[2]  Gebert Lfr,et al.  Regulation of microRNA function in animals , 2019 .

[3]  Chuan He,et al.  Publisher Correction: Post-transcriptional gene regulation by mRNA modifications , 2018, Nature Reviews Molecular Cell Biology.

[4]  T. Furey,et al.  Colonic epithelial miR-31 associates with the development of Crohn's phenotypes. , 2018, JCI insight.

[5]  G. Meister,et al.  Author Correction: Regulation of microRNA biogenesis and its crosstalk with other cellular pathways , 2018, Nature Reviews Molecular Cell Biology.

[6]  P. Jedlicka,et al.  miR-106a deficiency attenuates inflammation in murine IBD models. , 2018, Mucosal Immunology.

[7]  I. MacRae,et al.  Regulation of microRNA function in animals , 2018, Nature Reviews Molecular Cell Biology.

[8]  Dirk Baumjohann,et al.  Posttranscriptional Gene Regulation of T Follicular Helper Cells by RNA-Binding Proteins and microRNAs , 2018, Front. Immunol..

[9]  B. Oldenburg,et al.  The elusive case of human intraepithelial T cells in gut homeostasis and inflammation , 2018, Nature Reviews Gastroenterology & Hepatology.

[10]  B. Nakstad,et al.  Anti-Inflammatory MicroRNAs and Their Potential for Inflammatory Diseases Treatment , 2018, Front. Immunol..

[11]  Dongyan Wang,et al.  MiRNA-155 Regulates the Th17/Treg Ratio by Targeting SOCS1 in Severe Acute Pancreatitis , 2018, Front. Physiol..

[12]  Xi-Long Zheng,et al.  Transcriptional Regulation of Macrophages Polarization by MicroRNAs , 2018, Front. Immunol..

[13]  A. Ananthakrishnan,et al.  The role of diet in the aetiopathogenesis of inflammatory bowel disease , 2018, Nature Reviews Gastroenterology & Hepatology.

[14]  Hui-Kuan Lin,et al.  Critical Role of Alternative M2 Skewing in miR-155 Deletion-Mediated Protection of Colitis , 2018, Front. Immunol..

[15]  Z. Yao,et al.  MicroRNA-181c promotes Th17 cell differentiation and mediates experimental autoimmune encephalomyelitis , 2018, Brain, Behavior, and Immunity.

[16]  D. Baltimore,et al.  Epigenetic silencing of miR-125b is required for normal B-cell development. , 2018, Blood.

[17]  M. Regueiro,et al.  ACG Clinical Guideline: Management of Crohn’s Disease in Adults , 2018, The American Journal of Gastroenterology.

[18]  D. Bartel.  Metazoan MicroRNAs , 2018, Cell.

[19]  J. Freeman,et al.  MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation , 2018, Cell reports.

[20]  S. Bueno,et al.  Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation: Opposing Effects in Crohn’s Disease and Ulcerative Colitis , 2018, Front. Immunol..

[21]  Michael T. McManus,et al.  Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals. , 2018, Molecular cell.

[22]  M. Hirst,et al.  Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice , 2017 .

[23]  R. Locksley,et al.  MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation , 2017, The Journal of experimental medicine.

[24]  C. Croce,et al.  MicroRNAs in intestinal barrier function, inflammatory bowel disease and related cancers — their effects and therapeutic potentials , 2017, Current opinion in pharmacology.

[25]  H. Ikeuchi,et al.  A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer. , 2017, Gastroenterology.

[26]  A. Rudensky,et al.  An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses , 2017, Nature Communications.

[27]  K. Ebnet.  Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development. , 2017, Physiological reviews.

[28]  Manoj Kumar,et al.  Toward the human cellular microRNAome. , 2017, Genome research.

[29]  M. Boldin,et al.  miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. , 2017, The Journal of clinical investigation.

[30]  Amit Kumar Srivastava,et al.  The role of desmosomes in carcinogenesis , 2017, OncoTargets and therapy.

[31]  Andreas Keller,et al.  A comprehensive, cell specific microRNA catalogue of human peripheral blood , 2017, Nucleic acids research.

[32]  J. Inoue,et al.  miR-146a–Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression , 2017, Proceedings of the National Academy of Sciences.

[33]  Sergei B Koralov,et al.  miRNAs in B Cell Development and Lymphomagenesis. , 2017, Trends in molecular medicine.

[34]  S. Vermeire,et al.  The intestinal barrier: a fundamental role in health and disease , 2017, Expert review of gastroenterology & hepatology.

[35]  U. Testa,et al.  miR-146 and miR-155: Two Key Modulators of Immune Response and Tumor Development , 2017, Non-coding RNA.

[36]  M. Mack,et al.  Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome , 2017, The Journal of experimental medicine.

[37]  C. Langner,et al.  Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders. , 2017, Journal of Crohn's & colitis.

[38]  L. Peyrin-Biroulet,et al.  Ulcerative colitis , 2017, The Lancet.

[39]  V. Andersen,et al.  Expression and Localization of miR-21 and miR-126 in Mucosal Tissue from Patients with Inflammatory Bowel Disease , 2017, Inflammatory bowel diseases.

[40]  Andreas Keller,et al.  miRNA assays in the clinical laboratory: workflow, detection technologies and automation aspects , 2017, Clinical chemistry and laboratory medicine.

[41]  L. Peyrin-Biroulet,et al.  Crohn's disease , 2017, The Lancet.

[42]  Liu Hong,et al.  Role of MiRNAs in Inflammatory Bowel Disease , 2017, Digestive Diseases and Sciences.

[43]  Yu-qi Fan,et al.  MicroRNA-9 Inhibits NLRP3 Inflammasome Activation in Human Atherosclerosis Inflammation Cell Models through the JAK1/STAT Signaling Pathway , 2017, Cellular Physiology and Biochemistry.

[44]  Lei Ma,et al.  MicroRNA-155 promotes the pathogenesis of experimental colitis by repressing SHIP-1 expression , 2017, World journal of gastroenterology.

[45]  H. Tilg,et al.  3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 1 Diagnosis and Medical Management , 2017, Journal of Crohn's & colitis.

[46]  K. Okazaki,et al.  Downregulation of MicroRNA-21 in Colonic CD3+ T Cells in UC Remission , 2016, Inflammatory bowel diseases.

[47]  Sashwati Roy.  miRNA in Macrophage Development and Function. , 2016, Antioxidants & redox signaling.

[48]  Chen-feng Qi,et al.  Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5 , 2016, EBioMedicine.

[49]  A. Mangoni,et al.  MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis , 2016, Nature Communications.

[50]  R. Garzon,et al.  miR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency. , 2016, Blood.

[51]  N. Shomron,et al.  MicroRNAs Expression in the Ileal Pouch of Patients with Ulcerative Colitis Is Robustly Up-Regulated and Correlates with Disease Phenotypes , 2016, PloS one.

[52]  Yutian Li,et al.  MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response , 2016, Shock.

[53]  Cheng Huang,et al.  Emerging role of microRNAs in regulating macrophage activation and polarization in immune response and inflammation , 2016, Immunology.

[54]  G. Calin,et al.  Targeting microRNAs as key modulators of tumor immune response , 2016, Journal of Experimental & Clinical Cancer Research.

[55]  C. Xiao,et al.  The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression. , 2016, Immunity.

[56]  Dirk Baumjohann,et al.  Emerging Roles for MicroRNAs in T Follicular Helper Cell Differentiation. , 2016, Trends in immunology.

[57]  D. Baltimore,et al.  MicroRNAs as regulatory elements in immune system logic , 2016, Nature Reviews Immunology.

[58]  Michael T. McManus,et al.  MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production. , 2016, Immunity.

[59]  Jun Yu,et al.  Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease , 2016, Genome Biology.

[60]  G. Veres,et al.  Role of Altered Expression of miR-146a, miR-155, and miR-122 in Pediatric Patients with Inflammatory Bowel Disease , 2016, Inflammatory bowel diseases.

[61]  Minhu Chen,et al.  Circulating MicroRNA223 is a New Biomarker for Inflammatory Bowel Disease , 2016, Medicine.

[62]  H. Weiner,et al.  The Host Shapes the Gut Microbiota via Fecal MicroRNA. , 2016, Cell host & microbe.

[63]  C. Xiao,et al.  The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity , 2015, Nature Immunology.

[64]  C. Fiocchi,et al.  Immunopathogenesis of IBD: current state of the art , 2016, Nature Reviews Gastroenterology &Hepatology.

[65]  Li Wu,et al.  MicroRNA-223 Regulates the Differentiation and Function of Intestinal Dendritic Cells and Macrophages by Targeting C/EBPβ. , 2015, Cell reports.

[66]  D. Iliopoulos,et al.  Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology , 2015, Inflammatory bowel diseases.

[67]  A. Schambach,et al.  Responsiveness of Developing T Cells to IL-7 Signals Is Sustained by miR-17∼92 , 2015, The Journal of Immunology.

[68]  S. Szymczak,et al.  Sparse Modeling Reveals miRNA Signatures for Diagnostics of Inflammatory Bowel Disease , 2015, PloS one.

[69]  D. Iliopoulos,et al.  MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. , 2015, Gastroenterology.

[70]  A. Leung,et al.  The Whereabouts of microRNA Actions: Cytoplasm and Beyond. , 2015, Trends in cell biology.

[71]  D. Baltimore,et al.  The microRNA-212/132 cluster regulates B cell development by targeting Sox4 , 2015, The Journal of experimental medicine.

[72]  James C. Lee,et al.  Low Serum Levels of MicroRNA-19 Are Associated with a Stricturing Crohn's Disease Phenotype , 2015, Inflammatory bowel diseases.

[73]  Terrence S. Furey,et al.  MicroRNAs Classify Different Disease Behavior Phenotypes of Crohn's Disease and May Have Prognostic Utility , 2015, Inflammatory bowel diseases.

[74]  X. Chen,et al.  miR-19b downregulates intestinal SOCS3 to reduce intestinal inflammation in Crohn’s disease , 2015, Scientific Reports.

[75]  D. Iliopoulos,et al.  A MicroRNA Signature in Pediatric Ulcerative Colitis: Deregulation of the miR-4284/CXCL5 Pathway in the Intestinal Epithelium , 2015, Inflammatory bowel diseases.

[76]  C. Mason,et al.  miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. , 2015, Blood.

[77]  A. Iwasaki,et al.  Control of adaptive immunity by the innate immune system , 2015, Nature Immunology.

[78]  N. Yosef,et al.  MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis. , 2015, The Journal of clinical investigation.

[79]  M. Cooper,et al.  The early history of B cells , 2015, Nature Reviews Immunology.

[80]  B. Göttgens,et al.  MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome. , 2015, Blood.

[81]  A. Opekun,et al.  MicroRNA signatures differentiate Crohn’s disease from ulcerative colitis , 2015, BMC Immunology.

[82]  Jennifer A. Doudna,et al.  Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis. , 2015, Molecular cell.

[83]  R. Lechler,et al.  MicroRNAs affect dendritic cell function and phenotype , 2015, Immunology.

[84]  J. Pekow,et al.  The emerging role of miRNAs in inflammatory bowel disease: a review , 2015, Therapeutic advances in gastroenterology.

[85]  A. Skapenko,et al.  Decreased expression of miR-146a and miR-155 contributes to an abnormal Treg phenotype in patients with rheumatoid arthritis , 2014, Annals of the rheumatic diseases.

[86]  Katherine E. Twomey,et al.  Preemption versus Entrenchment: Towards a Construction-General Solution to the Problem of the Retreat from Verb Argument Structure Overgeneralization , 2015, PloS one.

[87]  Yanhong Wu,et al.  Adoptive T-cell therapy of prostate cancer targeting the cancer stem cell antigen EpCAM , 2015, BMC Immunology.

[88]  P. Rutgeerts,et al.  Integrated miRNA and mRNA Expression Profiling in Inflamed Colon of Patients with Ulcerative Colitis , 2014, PloS one.

[89]  A H Buck,et al.  MicroRNAs: new players in IBD , 2014, Gut.

[90]  W. Cho,et al.  microRNA-124 negatively regulates TLR signaling in alveolar macrophages in response to mycobacterial infection. , 2014, Molecular immunology.

[91]  D. Taub,et al.  miR‐155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses , 2014, Immunology.

[92]  C. Abreu-Goodger,et al.  The miR-155–PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation , 2014, The Journal of experimental medicine.

[93]  S. Werner,et al.  A novel Nrf2-miR-29-desmocollin-2 axis regulates desmosome function in keratinocytes , 2014, Nature Communications.

[94]  I. Pinchuk,et al.  miR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD , 2014, Gut.

[95]  R. Baldassano,et al.  Rectal microRNAs are perturbed in pediatric inflammatory bowel disease of the colon. , 2014, Journal of Crohn's & colitis.

[96]  Taro Kawai,et al.  Toll-Like Receptor Signaling Pathways , 2014, Front. Immunol..

[97]  M. Schmidt,et al.  MicroRNAs regulate tight junction proteins and modulate epithelial/endothelial barrier functions , 2014, Tissue barriers.

[98]  Thomas C Roberts,et al.  The MicroRNA Biology of the Mammalian Nucleus , 2014, Molecular therapy. Nucleic acids.

[99]  Yi Zhang,et al.  MicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation , 2014, Cell.

[100]  Markus F. Neurath,et al.  Cytokines in inflammatory bowel disease , 2014, Nature Reviews Immunology.

[101]  Min Guo,et al.  MicroRNA-155 Is Involved in the Pathogenesis of Ulcerative Colitis by Targeting FOXO3a , 2014, Inflammatory bowel diseases.

[102]  Baojun Zhang,et al.  miR-17-92 Cluster Targets Phosphatase and Tensin Homology and Ikaros Family Zinc Finger 4 to Promote TH17-mediated Inflammation* , 2014, The Journal of Biological Chemistry.

[103]  F. Seibold,et al.  Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy. , 2014, Gastroenterology.

[104]  Z. Zhai,et al.  NOD2 Expression is Regulated by microRNAs in Colonic Epithelial HCT116 Cells , 2014, Inflammatory bowel diseases.

[105]  V. Kim,et al.  Regulation of microRNA biogenesis , 2014, Nature Reviews Molecular Cell Biology.

[106]  B. Joseph,et al.  The return of the nucleus: transcriptional and epigenetic control of autophagy , 2013, Nature Reviews Molecular Cell Biology.

[107]  K. Sun,et al.  Anti-miRNA-221 sensitizes human colorectal carcinoma cells to radiation by upregulating PTEN. , 2013, World journal of gastroenterology.

[108]  K. Green,et al.  Desmosome assembly and dynamics. , 2013, Trends in cell biology.

[109]  A. Rao,et al.  MicroRNA-directed program of cytotoxic CD8+ T-cell differentiation , 2013, Proceedings of the National Academy of Sciences.

[110]  D. Iliopoulos,et al.  MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis. , 2013, Gastroenterology.

[111]  D. Jewell,et al.  The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release. , 2013, Immunity.

[112]  K. Mark Ansel,et al.  MicroRNA-mediated regulation of T helper cell differentiation and plasticity , 2013, Nature Reviews Immunology.

[113]  Jonathan H. Esensten,et al.  microRNA-17–92 Regulates IL-10 Production by Regulatory T Cells and Control of Experimental Autoimmune Encephalomyelitis , 2013, The Journal of Immunology.

[114]  F. Marabita,et al.  Identification of serum and tissue micro‐RNA expression profiles in different stages of inflammatory bowel disease , 2013, Clinical and experimental immunology.

[115]  Sang Gon Park,et al.  Colon cancer progression is driven by APEX1-mediated upregulation of Jagged. , 2013, The Journal of clinical investigation.

[116]  J. Bluestone,et al.  The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression , 2013, Nature Immunology.

[117]  Stefan L Ameres,et al.  Diversifying microRNA sequence and function , 2013, Nature Reviews Molecular Cell Biology.

[118]  H. Lodish,et al.  MicroRNA-126–mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors , 2013, Proceedings of the National Academy of Sciences.

[119]  Soyoung Lee,et al.  Aryl hydrocarbon receptor-mediated induction of the microRNA-132/212 cluster promotes interleukin-17–producing T-helper cell differentiation , 2013, Proceedings of the National Academy of Sciences.

[120]  Ryan M. O’Connell,et al.  MicroRNA-155 Confers Encephalogenic Potential to Th17 Cells by Promoting Effector Gene Expression , 2013, The Journal of Immunology.

[121]  J. Bluestone,et al.  miR-17~92 promotes T follicular helper cell differentiation and represses subset-inappropriate gene expression , 2013, Nature immunology.

[122]  Ryan M. O’Connell,et al.  MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice , 2013, eLife.

[123]  Yongzhi Yang,et al.  Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase RhoB. , 2013, Biochemical and biophysical research communications.

[124]  P. Romero,et al.  MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer. , 2013, Immunity.

[125]  Y. Wang,et al.  miR-200b inhibits TGF-β1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells , 2013, Cell Death and Disease.

[126]  M. Neunlist,et al.  The digestive neuronal–glial–epithelial unit: a new actor in gut health and disease , 2013, Nature Reviews Gastroenterology &Hepatology.

[127]  P. Gregersen,et al.  Regulation of dendritic cell activation by microRNA let-7c and BLIMP1. , 2013, The Journal of clinical investigation.

[128]  Yu Zhou,et al.  Up-Regulation of microRNA-126 May Contribute to Pathogenesis of Ulcerative Colitis via Regulating NF-kappaB Inhibitor IκBα , 2012, PloS one.

[129]  C. Bracken,et al.  IsomiRs--the overlooked repertoire in the dynamic microRNAome. , 2012, Trends in genetics : TIG.

[130]  Huanhuan Li,et al.  MicroRNA-155 Modulates Treg and Th17 Cells Differentiation and Th17 Cell Function by Targeting SOCS1 , 2012, PloS one.

[131]  M. Gazouli,et al.  Circulating MicroRNA in inflammatory bowel disease. , 2012, Journal of Crohn's & colitis.

[132]  J. Boeckel,et al.  MicroRNAs in platelet biogenesis and function: implications in vascular homeostasis and inflammation. , 2012, Current vascular pharmacology.

[133]  R. Tooze,et al.  BLIMP-1 and STAT3 Counterregulate MicroRNA-21 during Plasma Cell Differentiation , 2012, The Journal of Immunology.

[134]  J. O’Shea,et al.  TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells , 2012, Nature Immunology.

[135]  K. Selmaj,et al.  microRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination , 2012, Proceedings of the National Academy of Sciences.

[136]  Pietro Invernizzi,et al.  MicroRNAs in autoimmunity and inflammatory bowel disease: crucial regulators in immune response. , 2012, Autoimmunity reviews.

[137]  Keith W. Jones,et al.  Genome-Wide Maps of Circulating miRNA Biomarkers for Ulcerative Colitis , 2012, PloS one.

[138]  David L. A. Wood,et al.  MicroRNAs and their isomiRs function cooperatively to target common biological pathways , 2011, Genome Biology.

[139]  N. Vigneswaran,et al.  Selective Upregulation of microRNA Expression in Peripheral Blood Leukocytes in IL-10−/− Mice Precedes Expression in the Colon , 2011, The Journal of Immunology.

[140]  Xiuping Liu,et al.  Microbiota Downregulates Dendritic Cell Expression of miR-10a, Which Targets IL-12/IL-23p40 , 2011, The Journal of Immunology.

[141]  K. Zen,et al.  Role of miR‐150‐targeting c‐Myb in colonic epithelial disruption during dextran sulphate sodium‐induced murine experimental colitis and human ulcerative colitis , 2011, The Journal of pathology.

[142]  Bo W. Han,et al.  The 3′-to-5′ Exoribonuclease Nibbler Shapes the 3′ Ends of MicroRNAs Bound to Drosophila Argonaute1 , 2011, Current Biology.

[143]  Lin He,et al.  Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation. , 2011, Blood.

[144]  Yi Zheng,et al.  miR‐21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells , 2011, FEBS letters.

[145]  Xiongfei Xu,et al.  The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ , 2011, Nature Immunology.

[146]  K. Ansel,et al.  MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells. , 2011, Immunity.

[147]  M. Leonard,et al.  Circulating MicroRNA Is a Biomarker of Pediatric Crohn Disease , 2011, Journal of pediatric gastroenterology and nutrition.

[148]  K. Basso,et al.  Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150. , 2011, Blood.

[149]  S. Brant,et al.  Peripheral blood MicroRNAs distinguish active ulcerative colitis and Crohn's disease , 2011, Inflammatory bowel diseases.

[150]  Tariq Ahmad,et al.  Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci , 2010, Nature Genetics.

[151]  K. Kodys,et al.  Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease* , 2010, The Journal of Biological Chemistry.

[152]  David Galas,et al.  Complexity of the microRNA repertoire revealed by next-generation sequencing. , 2010, RNA.

[153]  Ryan M. O’Connell,et al.  MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. , 2010, Immunity.

[154]  E. Ogier-Denis,et al.  Identification of Restricted Subsets of Mature microRNA Abnormally Expressed in Inactive Colonic Mucosa of Patients with Inflammatory Bowel Disease , 2010, PloS one.

[155]  S. Brant,et al.  Identification of microRNAs associated with ileal and colonic Crohn's disease† , 2010, Inflammatory bowel diseases.

[156]  David Baltimore,et al.  Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses , 2010, Cell.

[157]  Lai Wei,et al.  Regulation of microRNA expression and abundance during lymphopoiesis. , 2010, Immunity.

[158]  Y. Naito,et al.  Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis , 2010, Journal of gastroenterology and hepatology.

[159]  Christian Gieger,et al.  Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL) , 2010, Nature Genetics.

[160]  A. Kornbluth,et al.  Ulcerative Colitis Practice Guidelines in Adults: American College of Gastroenterology, Practice Parameters Committee , 2010, The American Journal of Gastroenterology.

[161]  Ryan M. O’Connell,et al.  Physiological and pathological roles for microRNAs in the immune system , 2010, Nature Reviews Immunology.

[162]  D. Philpott,et al.  Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry , 2010, Nature Immunology.

[163]  D. Jewell,et al.  NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation , 2010, Nature Medicine.

[164]  Jiuhong Kang,et al.  MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis , 2009, Nature Immunology.

[165]  J. Lieberman,et al.  miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53. , 2009, Blood.

[166]  C. V. Van Itallie,et al.  Physiology and function of the tight junction. , 2009, Cold Spring Harbor perspectives in biology.

[167]  M. Lindsay,et al.  microRNAs and the immune response. , 2008, Trends in immunology.

[168]  Meenu R Pillai,et al.  The development and function of regulatory T cells , 2009, Cellular and Molecular Life Sciences.

[169]  P. Tak,et al.  MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. , 2009, Arthritis and rheumatism.

[170]  A. Mantovani,et al.  Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals , 2009, Proceedings of the National Academy of Sciences.

[171]  E. Vigorito,et al.  Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells1 , 2009, The Journal of Immunology.

[172]  Manuel A. S. Santos,et al.  MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells , 2009, Proceedings of the National Academy of Sciences.

[173]  Hana Lee,et al.  Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. , 2009, Immunity.

[174]  A. Kowalczyk,et al.  The desmosome. , 2009, Cold Spring Harbor perspectives in biology.

[175]  S. Barry,et al.  Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease , 2009, Journal of Clinical Immunology.

[176]  S. Brant,et al.  MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. , 2008, Gastroenterology.

[177]  W. Paul,et al.  CD4 T cells: fates, functions, and faults. , 2008, Blood.

[178]  Judy H. Cho,et al.  Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease , 2008, Nature Genetics.

[179]  Daniel B. Martin,et al.  Circulating microRNAs as stable blood-based markers for cancer detection , 2008, Proceedings of the National Academy of Sciences.

[180]  Shangqin Guo,et al.  MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. , 2008, Developmental cell.

[181]  M. Korpal,et al.  The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2* , 2008, Journal of Biological Chemistry.

[182]  Xiaowu Gai,et al.  A GATA-1-regulated microRNA locus essential for erythropoiesis , 2008, Proceedings of the National Academy of Sciences.

[183]  A. Michalsen,et al.  Noninvasive Markers in the Assessment of Intestinal Inflammation in Inflammatory Bowel Diseases: Performance of Fecal Lactoferrin, Calprotectin, and PMN-Elastase, CRP, and Clinical Indices , 2008, The American Journal of Gastroenterology.

[184]  Ellen V. Rothenberg,et al.  Launching the T-cell-lineage developmental programme , 2008, Nature Reviews Immunology.

[185]  Z. Ge,et al.  Relationship between fecal lactoferrin and inflammatory bowel disease , 2007, Scandinavian journal of gastroenterology.

[186]  D. Baltimore,et al.  NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses , 2006, Proceedings of the National Academy of Sciences.

[187]  Z. Halpern,et al.  Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn's disease. , 2006, Gastroenterology.

[188]  T. Nagasawa.  Microenvironmental niches in the bone marrow required for B-cell development , 2006, Nature Reviews Immunology.

[189]  Mads Hald Andersen,et al.  Cytotoxic T cells. , 2006, The Journal of investigative dermatology.

[190]  George A Calin,et al.  MicroRNA fingerprints during human megakaryocytopoiesis. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[191]  H. Horvitz,et al.  MicroRNA expression profiles classify human cancers , 2005, Nature.

[192]  D. Bartel,et al.  MicroRNAs Modulate Hematopoietic Lineage Differentiation , 2004, Science.

[193]  Alastair Forbes,et al.  The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease. , 2002, Gastroenterology.

[194]  M. Vatn,et al.  Inflammatory bowel disease: re-evaluation of the diagnosis in a prospective population based study in south eastern Norway. , 1997, Gut.

[195]  C. FordAlexander,et al.  ULCERATIVE colitis. , 1997, Journal of the American Medical Association.