β2 subunit containing acetylcholine receptors mediate nicotine withdrawal deficits in the acquisition of contextual fear conditioning

[1]  R. J. Mather,et al.  Pharmacological profile of the α4β2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid , 2007, Neuropharmacology.

[2]  T. Gould,et al.  β2 subunit-containing nicotinic receptors mediate the enhancing effect of nicotine on trace cued fear conditioning in C57BL/6 mice , 2007, Psychopharmacology.

[3]  T. Gould,et al.  Atomoxetine Reverses Nicotine Withdrawal-Associated Deficits in Contextual Fear Conditioning , 2007, Neuropsychopharmacology.

[4]  Jason Gong,et al.  Efficacy of Varenicline, an 42 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation A Randomized Controlled Trial , 2006 .

[5]  David Gonzales,et al.  Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Sustained-Release Bupropion and Placebo for Smoking Cessation: A Randomized Controlled Trial , 2006 .

[6]  K. Pugh,et al.  Visuospatial Memory Deficits Emerging During Nicotine Withdrawal in Adolescents with Prenatal Exposure to Active Maternal Smoking , 2006, Neuropsychopharmacology.

[7]  J. Changeux,et al.  Genetic dissociation of two behaviors associated with nicotine addiction: Beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome , 2006, Psychopharmacology.

[8]  P. Kenny,et al.  Nicotine Self-Administration Acutely Activates Brain Reward Systems and Induces a Long-Lasting Increase in Reward Sensitivity , 2006, Neuropsychopharmacology.

[9]  Mark S. Cohen,et al.  Working memory in cigarette smokers: comparison to non-smokers and effects of abstinence. , 2006, Addictive behaviors.

[10]  D. Lancet,et al.  Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes , 2006, Molecular Psychiatry.

[11]  T. Gould,et al.  The effects of DHBE and MLA on nicotine-induced enhancement of contextual fear conditioning in C57BL/6 mice , 2006, Psychopharmacology.

[12]  J. Changeux,et al.  The β2 but not α7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice , 2006, Psychopharmacology.

[13]  S. Siegel,et al.  Withdrawal from Chronic Nicotine Administration Impairs Contextual Fear Conditioning in C57BL/6 Mice , 2005, The Journal of Neuroscience.

[14]  M. Lewis,et al.  Coantagonism of glutamate receptors and nicotinic acetylcholinergic receptors disrupts fear conditioning and latent inhibition of fear conditioning. , 2005, Learning & memory.

[15]  Ming D. Li,et al.  Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence. , 2005, Human molecular genetics.

[16]  Robert A Koeppe,et al.  Regional cerebral blood flow responses to smoking in tobacco smokers after overnight abstinence. , 2005, The American journal of psychiatry.

[17]  L. Bizarro,et al.  Deficits in a sustained attention task following nicotine withdrawal in rats , 2005, Psychopharmacology.

[18]  A. C. Collins,et al.  Modulation of nicotine but not ethanol preference by the mouse Chrna4 A529T polymorphism. , 2005, Behavioral neuroscience.

[19]  John H. Krystal,et al.  Effects of smoking and smoking abstinence on cognition in adolescent tobacco smokers , 2005, Biological Psychiatry.

[20]  A. Beaudet,et al.  Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning , 2004, Neuroscience.

[21]  R. Salas,et al.  Decreased Signs of Nicotine Withdrawal in Mice Null for the β4 Nicotinic Acetylcholine Receptor Subunit , 2004, The Journal of Neuroscience.

[22]  Tianhua Niu,et al.  A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men. , 2004, American journal of human genetics.

[23]  J. Gerberding,et al.  Actual causes of death in the United States, 2000. , 2004, JAMA.

[24]  T. Baker,et al.  Motivational influences on cigarette smoking. , 2004, Annual review of psychology.

[25]  H. Mansvelder,et al.  Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. , 2003, European journal of pharmacology.

[26]  M. Damaj,et al.  Characterization of Spontaneous and Precipitated Nicotine Withdrawal in the Mouse , 2003, Journal of Pharmacology and Experimental Therapeutics.

[27]  J. S. Higgins,et al.  Nicotine enhances contextual fear conditioning in C57BL/6J mice at 1 and 7 days post-training , 2003, Neurobiology of Learning and Memory.

[28]  A. C. Collins,et al.  A polymorphism in the alpha4 nicotinic receptor gene (Chrna4) modulates enhancement of nicotinic receptor function by ethanol. , 2003, Alcoholism, clinical and experimental research.

[29]  J. Changeux,et al.  The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. , 2002, Journal of neurobiology.

[30]  E. Nestler,et al.  Common Molecular and Cellular Substrates of Addiction and Memory , 2002, Neurobiology of Learning and Memory.

[31]  A. C. Collins,et al.  A polymorphism in the mouse neuronal alpha4 nicotinic receptor subunit results in an alteration in receptor function. , 2002, Molecular pharmacology.

[32]  D. Rubin,et al.  Activation in mesolimbic and visuospatial neural circuits elicited by smoking cues: evidence from functional magnetic resonance imaging. , 2002, The American journal of psychiatry.

[33]  D. Hamer,et al.  Genetic and functional analysis of single nucleotide polymorphisms in the beta2-neuronal nicotinic acetylcholine receptor gene (CHRNB2). , 2002, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

[34]  A. Harrison,et al.  Nicotine potentiation of brain stimulation reward reversed by DHβE and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats , 2002, Psychopharmacology.

[35]  A. Markou,et al.  The nicotinic antagonist methyllycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat. , 2001, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

[36]  A. C. Collins,et al.  Long sleep and short sleep mice differ in nicotine-stimulated 86Rb+ efflux and alpha4 nicotinic receptor subunit cDNA sequence. , 2001, Pharmacogenetics.

[37]  R. Papke,et al.  Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes. , 2001, The Journal of pharmacology and experimental therapeutics.

[38]  M. Picciotto,et al.  Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain , 2000, Neuropharmacology.

[39]  P. Sullivan,et al.  Haplotypes of four novel single nucleotide polymorphisms in the nicotinic acetylcholine receptor beta2-subunit (CHRNB2) gene show no association with smoking initiation or nicotine dependence. , 2000, American journal of medical genetics.

[40]  G. Higgins,et al.  Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine. , 2000, The Journal of pharmacology and experimental therapeutics.

[41]  J P Changeux,et al.  Nicotinic receptor function: new perspectives from knockout mice. , 2000, Trends in pharmacological sciences.

[42]  Arthur L. Beaudet,et al.  Multiorgan Autonomic Dysfunction in Mice Lacking the β2 and the β4 Subunits of Neuronal Nicotinic Acetylcholine Receptors , 1999, The Journal of Neuroscience.

[43]  J. Wehner,et al.  Nicotine enhancement of contextual fear conditioning , 1999, Behavioural Brain Research.

[44]  G. Koob,et al.  Dramatic decreases in brain reward function during nicotine withdrawal , 1998, Nature.

[45]  J. Changeux,et al.  Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine , 1998, Nature.

[46]  A. Beaudet,et al.  Mice Deficient in the α7 Neuronal Nicotinic Acetylcholine Receptor Lack α-Bungarotoxin Binding Sites and Hippocampal Fast Nicotinic Currents , 1997, The Journal of Neuroscience.

[47]  R. Lester,et al.  Influence of Subunit Composition on Desensitization of Neuronal Acetylcholine Receptors at Low Concentrations of Nicotine , 1997, The Journal of Neuroscience.

[48]  R. Paylor,et al.  Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task. , 1997, Behavioral neuroscience.

[49]  C. Luetje,et al.  Multiple Determinants of Dihydro‐β‐Erythroidine Sensitivity on Rat Neuronal Nicotinic Receptor α Subunits , 1996 .

[50]  J. Susman,et al.  Physician counseling for smoking cessation: is the glass half empty? , 1995, The Journal of family practice.

[51]  W K Bickel,et al.  Nicotine withdrawal versus other drug withdrawal syndromes: similarities and dissimilarities. , 1994, Addiction.

[52]  W. Corrigall,et al.  Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area , 1994, Brain Research.

[53]  P. Blackman.  Actual causes of death in the United States. , 1994, JAMA.

[54]  J. Henningfield,et al.  Nicotine delivery kinetics and abuse liability. , 1993, Journal of consulting and clinical psychology.

[55]  M. Fanselow,et al.  Modality-specific retrograde amnesia of fear. , 1992, Science.

[56]  Joseph E LeDoux,et al.  Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. , 1992, Behavioral neuroscience.

[57]  D. Overton,et al.  Historical context of state dependent learning and discriminative drug effects. , 1991, Behavioural pharmacology.

[58]  M. Williams,et al.  Binding of the nicotinic cholinergic antagonist, dihydro-beta- erythroidine, to rat brain tissue , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[59]  G. O. Lignac.  [Actual causes of death]. , 1951, Nederlands tijdschrift voor geneeskunde.

[60]  R. Hurst,et al.  Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid. , 2007, Neuropharmacology.

[61]  S. Rennard,et al.  Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial. , 2006, JAMA.

[62]  N. Rigotti,et al.  Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. , 2006, JAMA.

[63]  D. Bertrand,et al.  Nicotinic acetylcholine receptors: from structure to brain function. , 2003, Reviews of physiology, biochemistry and pharmacology.

[64]  A. Beaudet,et al.  Multiorgan autonomic dysfunction in mice lacking the beta2 and the beta4 subunits of neuronal nicotinic acetylcholine receptors. , 1999, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[65]  A. Beaudet,et al.  Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents. , 1997, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[66]  C. Luetje,et al.  Multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal nicotinic receptor alpha subunits. , 1996, Journal of neurochemistry.

[67]  J R Hughes,et al.  Symptoms of tobacco withdrawal. A replication and extension. , 1991, Archives of general psychiatry.

[68]  N. Benowitz,et al.  Nicotine dependence and tolerance in man: pharmacokinetic and pharmacodynamic investigations. , 1989, Progress in brain research.