Looking back and thinking forwards — 15 years of cardiology and cardiovascular research

[1]  Jun Liu,et al.  Association of Serum Potassium Levels with Mortality and Cardiovascular Events: Findings from the Chinese Multi-provincial Cohort Study , 2021, Journal of General Internal Medicine.

[2]  Septimiu E. Salcudean,et al.  A new era: artificial intelligence and machine learning in prostate cancer , 2019, Nature Reviews Urology.

[3]  P. Ridker,et al.  Lipid levels and the risk of hemorrhagic stroke among women , 2019, Neurology.

[4]  Kavita Sharma,et al.  Nitrosative stress drives heart failure with preserved ejection fraction , 2019, Nature.

[5]  G. Hindricks,et al.  Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial , 2019, JAMA.

[6]  K. Anstrom,et al.  Effect of Catheter Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial , 2019, JAMA.

[7]  G. Butrous,et al.  Infection in pulmonary vascular diseases: Would another consortium really be the way to go? , 2019, Global cardiology science & practice.

[8]  F. Ginhoux,et al.  Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches , 2019, Science.

[9]  Eric Topol,et al.  Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again , 2019 .

[10]  Robert D. Atkinson,et al.  Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again , 2019 .

[11]  S. Pocock,et al.  Ambulatory heart rate reduction after catheter-based renal denervation in hypertensive patients not receiving anti-hypertensive medications: data from SPYRAL HTN-OFF MED, a randomized, sham-controlled, proof-of-concept trial , 2019, European heart journal.

[12]  A. Roddick,et al.  Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis , 2019, JAMA.

[13]  C. Sudlow,et al.  Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226) , 2019, Neurology.

[14]  U. Landmesser,et al.  Maintaining Cardiovascular Health in the digital era , 2019, European heart journal.

[15]  T. Arndt,et al.  In vivo , 2019, Springer Reference Medizin.

[16]  Shoba Ranganathan,et al.  Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics , 2019 .

[17]  E. Wolf,et al.  Consistent success in life-supporting porcine cardiac xenotransplantation , 2018, Nature.

[18]  David Tsay,et al.  From Machine Learning to Artificial Intelligence Applications in Cardiac Care. , 2018, Circulation.

[19]  S. Knecht,et al.  Improving procedural and one-year outcome after contact force-guided pulmonary vein isolation: the role of interlesion distance, ablation index, and contact force variability in the 'CLOSE'-protocol. , 2018, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[20]  M. Yacoub,et al.  The expanding role of implantable devices to monitor heart failure and pulmonary hypertension , 2018, Nature Reviews Cardiology.

[21]  R. Collins,et al.  Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus , 2018, The New England journal of medicine.

[22]  M. Böhm,et al.  Catheter-based renal denervation: the next chapter begins. , 2018, European heart journal.

[23]  P. Whelton,et al.  Prevention and Control of Hypertension: JACC Health Promotion Series. , 2018, Journal of the American College of Cardiology.

[24]  P. Rothwell,et al.  Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial , 2018, The Lancet.

[25]  Yan Li,et al.  Twenty-year epidemiologic study on LDL-C levels in relation to the risks of atherosclerotic event, hemorrhagic stroke, and cancer death among young and middle-aged population in China. , 2018, Journal of clinical lipidology.

[26]  S. Yusuf,et al.  Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study , 2018, The Lancet.

[27]  M. Yacoub,et al.  Pulmonary hypertension: the unaddressed global health burden. , 2018, The Lancet. Respiratory medicine.

[28]  S. Pocock,et al.  Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial , 2018, The Lancet.

[29]  Wilbert S Aronow,et al.  2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. , 2018, Hypertension.

[30]  J. Williamson,et al.  2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. , 2018, Hypertension.

[31]  Neil Chapman,et al.  Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial , 2018, The Lancet.

[32]  D. Kreisel,et al.  The Human Heart Contains Distinct Macrophage Subsets with Divergent Origins and Functions , 2018, Nature Medicine.

[33]  E. Ashley,et al.  Cardiovascular Precision Medicine in the Genomics Era , 2018, JACC. Basic to translational science.

[34]  L. Jordaens,et al.  Catheter Ablation for Atrial Fibrillation with Heart Failure , 2018, The New England journal of medicine.

[35]  S. Large,et al.  Heart transplantation from donation after circulatory determined death. , 2018, Annals of cardiothoracic surgery.

[36]  R. Brook,et al.  2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. , 2018, Journal of the American Society of Hypertension : JASH.

[37]  Erratum to: ‘Proceedings from the 2nd European Clinical Consensus Conference for device-based therapies for hypertension: state of the art and considerations for the future , 2017, European heart journal.

[38]  R. Krauss,et al.  Low-density lipoproteins cause atherosclerotic cardiovascular disease , 2018 .

[39]  Neil Chapman,et al.  Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial , 2017, The Lancet.

[40]  S. Yusuf,et al.  World Heart Federation Cholesterol Roadmap. , 2017, Global heart.

[41]  P. Libby,et al.  Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease , 2017, The New England journal of medicine.

[42]  Prashanthan Sanders,et al.  Modifiable Risk Factors and Atrial Fibrillation , 2017, Circulation.

[43]  S. Yusuf,et al.  Eliminating acute rheumatic fever and rheumatic heart disease , 2017, The Lancet.

[44]  R. Pierson,et al.  Selection of Patients for Initial Clinical Trials of Solid Organ Xenotransplantation. , 2017, Transplantation.

[45]  M. Humbert,et al.  Epidemiology and treatment of pulmonary arterial hypertension , 2017, Nature Reviews Cardiology.

[46]  K. Khunti,et al.  Lower Risk of Heart Failure and Death in Patients Initiated on Sodium-Glucose Cotransporter-2 Inhibitors Versus Other Glucose-Lowering Drugs , 2017, Circulation.

[47]  G. Chatellier,et al.  Proceedings from the 2nd European Clinical Consensus Conference for device-based therapies for hypertension: state of the art and considerations for the future , 2017, European heart journal.

[48]  Akshay S. Desai,et al.  Effect of sacubitril/valsartan versus enalapril on glycaemic control in patients with heart failure and diabetes: a post-hoc analysis from the PARADIGM-HF trial. , 2017, The lancet. Diabetes & endocrinology.

[49]  Lale Tokgözoğlu,et al.  Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel , 2017, European heart journal.

[50]  Andrej J. Savol,et al.  Macrophages Facilitate Electrical Conduction in the Heart , 2017, Cell.

[51]  M. Yacoub,et al.  Left Ventricular Assist Device as a Bridge to Recovery for Patients With Advanced Heart Failure , 2017, Journal of the American College of Cardiology.

[52]  A. Keech,et al.  Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease , 2017, The New England journal of medicine.

[53]  E. Fisher,et al.  Inflammatory processes in cardiovascular disease: a route to targeted therapies , 2017, Nature Reviews Cardiology.

[54]  Ivy Shiue,et al.  Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015 , 2017, JAMA.

[55]  S. Fullerton,et al.  Genomics is failing on diversity , 2016, Nature.

[56]  M. Madani Surgical Treatment of Chronic Thromboembolic Pulmonary Hypertension: Pulmonary Thromboendarterectomy. , 2016, Methodist DeBakey cardiovascular journal.

[57]  Deepak Srivastava,et al.  In Vivo Cellular Reprogramming: The Next Generation , 2016, Cell.

[58]  J. Staessen,et al.  Evaluation of Adherence Should Become an Integral Part of Assessment of Patients With Apparently Treatment-Resistant Hypertension , 2016, Hypertension.

[59]  E. Wolf,et al.  Efficient production of multi-modified pigs for xenotransplantation by ‘combineering’, gene stacking and gene editing , 2016, Scientific Reports.

[60]  I. Y. Chen,et al.  Induced pluripotent stem cells: at the heart of cardiovascular precision medicine , 2016, Nature Reviews Cardiology.

[61]  S. Jacobsen,et al.  Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. , 2016, Circulation research.

[62]  D. Arnett,et al.  The Role of Healthy Lifestyle in the Primordial Prevention of Cardiovascular Disease , 2016, Current Cardiology Reports.

[63]  J. Berry,et al.  Lifetime Perspectives on Primary Prevention of Atherosclerotic Cardiovascular Disease. , 2016, JAMA.

[64]  S. Pocock,et al.  Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation. , 2016, The New England journal of medicine.

[65]  M. Humbert,et al.  A global view of pulmonary hypertension. , 2016, The Lancet. Respiratory medicine.

[66]  Heart failure: SGLT2 inhibitors and heart failure — clinical implications , 2016, Nature Reviews Cardiology.

[67]  L. Friberg,et al.  Catheter ablation for atrial fibrillation is associated with lower incidence of stroke and death: data from Swedish health registries. , 2016, European heart journal.

[68]  N. Rosenthal,et al.  Revisiting Cardiac Cellular Composition. , 2016, Circulation research.

[69]  Andrea K. Chomistek,et al.  Association Between a Healthy Heart Score and the Development of Clinical Cardiovascular Risk Factors Among Women: Potential Role for Primordial Prevention , 2016, Circulation. Cardiovascular quality and outcomes.

[70]  Carla M. T. Bauer,et al.  Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth , 2015, Nature Immunology.

[71]  B. Zinman,et al.  Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. , 2015, The New England journal of medicine.

[72]  Muhammad Mamdani,et al.  Next Steps in Primary Prevention of Coronary Heart Disease: Rationale for and Design of the ECAD Trial. , 2015, Journal of the American College of Cardiology.

[73]  G. Chatellier,et al.  Proceedings from the European clinical consensus conference for renal denervation: considerations on future clinical trial design. , 2015, European heart journal.

[74]  M. Yacoub Cardiac donation after circulatory death: a time to reflect , 2015, The Lancet.

[75]  P. Gosse,et al.  Optimum and stepped care standardised antihypertensive treatment with or without renal denervation for resistant hypertension (DENERHTN): a multicentre, open-label, randomised controlled trial , 2015, The Lancet.

[76]  Prashanthan Sanders,et al.  Approaches to catheter ablation for persistent atrial fibrillation. , 2015, The New England journal of medicine.

[77]  Jennifer G. Robinson,et al.  Efficacy and safety of alirocumab in reducing lipids and cardiovascular events. , 2015, The New England journal of medicine.

[78]  U. Schotten,et al.  Catheter-Based Renal Denervation Reduces Atrial Nerve Sprouting and Complexity of Atrial Fibrillation in Goats , 2015, Circulation. Arrhythmia and electrophysiology.

[79]  S. Lai,et al.  Status of cardiovascular health in Chinese adults. , 2015, Journal of the American College of Cardiology.

[80]  Jun Liu,et al.  Lifetime risk for cardiovascular disease in a Chinese population: the Chinese Multi–Provincial Cohort Study , 2015, European journal of preventive cardiology.

[81]  Deepak L. Bhatt,et al.  Predictors of blood pressure response in the SYMPLICITY HTN-3 trial. , 2015, European heart journal.

[82]  Christie M. Ballantyne,et al.  Lipid lowering with PCSK9 inhibitors , 2014, Nature Reviews Cardiology.

[83]  Akshay S. Desai,et al.  Angiotensin-neprilysin inhibition versus enalapril in heart failure. , 2014, The New England journal of medicine.

[84]  A. Nair,et al.  The burden of pulmonary hypertension in resource-limited settings. , 2014, Global heart.

[85]  Douglas L. Packer,et al.  Paroxysmal AF catheter ablation with a contact force sensing catheter: results of the prospective, multicenter SMART-AF trial. , 2014, Journal of the American College of Cardiology.

[86]  S. Yusuf,et al.  Urinary sodium and potassium excretion, mortality, and cardiovascular events. , 2014, The New England journal of medicine.

[87]  M. Böhm,et al.  Renal denervation for the treatment of cardiovascular high risk-hypertension or beyond? , 2014, Circulation research.

[88]  Darrel P Francis,et al.  Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117 411 patients , 2014, BMJ : British Medical Journal.

[89]  R. Weissleder,et al.  Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction , 2014, Circulation research.

[90]  H. Krum,et al.  Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial. , 2014, European heart journal.

[91]  P. Pais,et al.  Darapladib for preventing ischemic events in stable coronary heart disease. , 2014, The New England journal of medicine.

[92]  Deepak L. Bhatt,et al.  Refining calcium test for diagnosis of medullary thyroid cancer: cutoffs, procedures and safety , 2014, The New England journal of medicine.

[93]  E. Olson,et al.  Macrophages are required for neonatal heart regeneration. , 2014, The Journal of clinical investigation.

[94]  Michael Böhm,et al.  Percutaneous renal denervation in patients with treatment-resistant hypertension: final 3-year report of the Symplicity HTN-1 study , 2014, The Lancet.

[95]  Ansuman T. Satpathy,et al.  Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. , 2014, Immunity.

[96]  E. Chao SGLT-2 Inhibitors: A New Mechanism for Glycemic Control , 2014, Clinical Diabetes.

[97]  Magdi H. Yacoub,et al.  Hydrogel scaffolds for tissue engineering: Progress and challenges , 2013, Global cardiology science & practice.

[98]  N. Rosenthal,et al.  Macrophages are required for adult salamander limb regeneration , 2013, Proceedings of the National Academy of Sciences.

[99]  H. Krum,et al.  Substantial Reduction in Single Sympathetic Nerve Firing After Renal Denervation in Patients With Resistant Hypertension , 2013, Hypertension.

[100]  Markus Abt,et al.  Effects of dalcetrapib in patients with a recent acute coronary syndrome. , 2012, The New England journal of medicine.

[101]  U. Schotten,et al.  Renal Sympathetic Denervation Suppresses Postapneic Blood Pressure Rises and Atrial Fibrillation in a Model for Sleep Apnea , 2012, Hypertension.

[102]  N. Rosenthal,et al.  An Abundant Tissue Macrophage Population in the Adult Murine Heart with a Distinct Alternatively-Activated Macrophage Profile , 2012, PloS one.

[103]  J. Atherton Stage B heart failure: rationale for screening. , 2012, Heart failure clinics.

[104]  P. Libby,et al.  Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis , 2012, The Journal of experimental medicine.

[105]  D. Bick Time to reflect. , 2011, Midwifery.

[106]  M. Yacoub,et al.  Bridge to recovery and the search for decision nodes. , 2011, Circulation. Heart failure.

[107]  G. Butrous,et al.  Pulmonary vascular disease associated with schistosomiasis , 2010, Expert review of anti-infective therapy.

[108]  K. Kuck,et al.  Fatal End of a Safety Algorithm for Pulmonary Vein Isolation With Use of High-Intensity Focused Ultrasound , 2010, Circulation. Arrhythmia and electrophysiology.

[109]  R. Sarangapani,et al.  Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual‐Acting Angiotensin Receptor—Neprilysin Inhibitor (ARNi) , 2010, Journal of clinical pharmacology.

[110]  H. Krum,et al.  Renal sympathetic-nerve ablation for uncontrolled hypertension. , 2009, The New England journal of medicine.

[111]  David O. Martin,et al.  Pulmonary vein antral isolation using an open irrigation ablation catheter for the treatment of atrial fibrillation: a randomized pilot study. , 2007, Journal of the American College of Cardiology.

[112]  G. Collins The next generation. , 2006, Scientific American.

[113]  Thomas R. Riley,et al.  A Randomized Double-blind Placebo-controlled Trial , 2004 .

[114]  E. Wright,et al.  Renal Na(+)-glucose cotransporters. , 2001, American journal of physiology. Renal physiology.

[115]  J Clémenty,et al.  Electrophysiological end point for catheter ablation of atrial fibrillation initiated from multiple pulmonary venous foci. , 2000, Circulation.

[116]  J Clémenty,et al.  Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. , 1998, The New England journal of medicine.

[117]  S. Jamieson Pulmonary thromboendarterectomy , 1998, Heart.