Fas and Fas ligand: a death factor and its receptor.

[1]  H Hengartner,et al.  Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. , 1994, Science.

[2]  Hans Hengartner,et al.  Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice , 1994, Nature.

[3]  C. Ware,et al.  A lymphotoxin-beta-specific receptor. , 1994, Science.

[4]  N. Jenkins,et al.  Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand , 1994, Cell.

[5]  S. Nagata,et al.  Purification and characterization of the Fas-ligand that induces apoptosis , 1994, The Journal of experimental medicine.

[6]  Takashi Suda,et al.  Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family , 1993, Cell.

[7]  N. Brot,et al.  The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[8]  F. Chisari,et al.  Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis , 1993, The Journal of experimental medicine.

[9]  N. Copeland,et al.  Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor , 1993, European journal of immunology.

[10]  R. Eisenberg,et al.  Selection of the T cell receptor repertoire in Lpr mice. , 1993, Journal of immunology.

[11]  L. Tartaglia,et al.  A novel domain within the 55 kd TNF receptor signals cell death , 1993, Cell.

[12]  S. Nagata,et al.  Lethal effect of the anti-Fas antibody in mice , 1993, Nature.

[13]  J. Mountz,et al.  Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene , 1993, The Journal of experimental medicine.

[14]  K. Elkon,et al.  The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn , 1993, The Journal of experimental medicine.

[15]  S. Nagata,et al.  Effect of bcl-2 on Fas antigen-mediated cell death. , 1993, Journal of immunology.

[16]  N. Copeland,et al.  CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF , 1993, Cell.

[17]  P. Krammer,et al.  Activation interferes with the APO-1 pathway in mature human T cells. , 1993, International immunology.

[18]  M. Sitkovsky,et al.  Cell-mediated cytotoxicity: contact and secreted factors. , 1993, Current opinion in immunology.

[19]  S. Nagata,et al.  A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. , 1993, The Journal of biological chemistry.

[20]  C. Weaver,et al.  Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[21]  D. Banner,et al.  Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation , 1993, Cell.

[22]  G. Sutherland,et al.  Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor , 1993, Cell.

[23]  J. Mountz,et al.  Origin of CD4-CD8-B220+ T cells in MRL-lpr/lpr mice. Clues from a T cell receptor beta transgenic mouse. , 1993, Journal of immunology.

[24]  P. Möller,et al.  Coregulation of the APO-1 antigen with intercellular adhesion molecule-1 (CD54) in tonsillar B cells and coordinate expression in follicular center B cells and in follicle center and mediastinal B-cell lymphomas. , 1993, Blood.

[25]  Carl F. Ware,et al.  Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface , 1993, Cell.

[26]  T. Uede,et al.  Transcriptional repression and differential splicing of Fas mRNA by early transposon (ETn) insertion in autoimmune lpr mice. , 1993, Biochemical and biophysical research communications.

[27]  S. Nagata,et al.  Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[28]  P. Golstein,et al.  Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity , 1993, The Journal of experimental medicine.

[29]  P. Möller,et al.  Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens. , 1992, Journal of immunology.

[30]  J. Inazawa,et al.  Assignment of the human Fas antigen gene (Fas) to 10q24.1. , 1992, Genomics.

[31]  T. Farrah,et al.  Emerging cytokine family , 1992, Nature.

[32]  G. Lenoir,et al.  Expression of the APO-1 antigen in Burkitt lymphoma cell lines correlates with a shift towards a lymphoblastoid phenotype. , 1992, Blood.

[33]  M. Pawlita,et al.  Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. , 1992, The Journal of biological chemistry.

[34]  E. Clark,et al.  Molecular and biological characterization of a murine ligand for CD40 , 1992, Nature.

[35]  M. Raff,et al.  Social controls on cell survival and cell death , 1992, Nature.

[36]  N. Copeland,et al.  Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis , 1992, Nature.

[37]  L. Owen-Schaub,et al.  DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement. , 1992, Cellular immunology.

[38]  N. Copeland,et al.  The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. , 1992, Journal of immunology.

[39]  H. Stein,et al.  Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease , 1992, Cell.

[40]  C. Ware,et al.  Lymphotoxin is expressed as a heteromeric complex with a distinct 33-kDa glycoprotein on the surface of an activated human T cell hybridoma. , 1992, Journal of Biological Chemistry.

[41]  S R Sprang,et al.  The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution. , 1992, The Journal of biological chemistry.

[42]  F. Chisari.  Hepatitis B virus biology and pathogenesis. , 1992, Molecular genetic medicine.

[43]  B. Seed,et al.  The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. , 1991, Journal of immunology.

[44]  L. Tartaglia,et al.  The two different receptors for tumor necrosis factor mediate distinct cellular responses. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[45]  Atsushi Hase,et al.  The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis , 1991, Cell.

[46]  J. D. Young,et al.  Cell Death Mechanisms and the Immune System , 1991, Immunological reviews.

[47]  E. Podack,et al.  A central role of perforin in cytolysis? , 1991, Annual review of immunology.

[48]  R. Eisenberg,et al.  Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. , 1991, Annual review of immunology.

[49]  H. Horvitz,et al.  Mechanisms and functions of cell death. , 1991, Annual review of cell biology.

[50]  N. Yamamoto,et al.  Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[51]  J. D. Marshall,et al.  Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of molecules. , 1990, The Journal of experimental medicine.

[52]  F. Ramsdell,et al.  Clonal deletion versus clonal anergy: the role of the thymus in inducing self tolerance. , 1990, Science.

[53]  C. Smith,et al.  A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. , 1990, Science.

[54]  G. Wong,et al.  Molecular cloning and expression of a receptor for human tumor necrosis factor , 1990, Cell.

[55]  A. Barclay,et al.  Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes‐‐a molecule related to nerve growth factor receptor. , 1990, The EMBO journal.

[56]  T. Waldmann,et al.  Monoclonal-antibody-mediated apoptosis in adult T-cell leukaemia , 1990, The Lancet.

[57]  T. Katagiri,et al.  A new allele of the lpr locus, lprcg, that complements the gld gene in induction of lymphadenopathy in the mouse , 1990, The Journal of experimental medicine.

[58]  P. Möller,et al.  Monoclonal antibody-mediated tumor regression by induction of apoptosis. , 1989, Science.

[59]  I. Stamenkovic,et al.  A B‐lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. , 1989, The EMBO journal.

[60]  S. Yonehara,et al.  A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor , 1989, The Journal of experimental medicine.

[61]  S. Weissman,et al.  cDNA sequences of two inducible T-cell genes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[62]  M. Spiess,et al.  A hepatocyte-specific basolateral membrane protein is targeted to the same domain when expressed in Madin-Darby canine kidney cells. , 1989, The Journal of biological chemistry.

[63]  C. Perez,et al.  A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF , 1988, Cell.

[64]  J. Kerr,et al.  Patterns of cell death. , 1988, Methods and achievements in experimental pathology.

[65]  R. Smith,et al.  The active form of tumor necrosis factor is a trimer. , 1987, The Journal of biological chemistry.

[66]  M. Chao,et al.  Expression and structure of the human NGF receptor , 1986, Cell.

[67]  L. Old,et al.  Tumor necrosis factor (TNF). , 1985, Science.

[68]  Bharat B. Aggarwal,et al.  Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin , 1984, Nature.

[69]  B. Aggarwal,et al.  Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity , 1984, Nature.

[70]  P. Brûlet,et al.  Early differential tissue expression of transposon-like repetitive DNA sequences of the mouse. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[71]  A. Wyllie,et al.  Cell death: the significance of apoptosis. , 1980, International review of cytology.