Editorial: escalation to weekly dosing in adalimumab‐treated patients with active ulcerative colitis

activity. For instance, investigation of novel therapeutic approaches could bypass UV trials, with their potential health risks, and more efficiently focus on trials based on more direct mechanisms. At the moment, it is unclear whether the effect of UV light on disease activity is independent of or dependent on vitamin D. If independent, then a new direction of UV-related research can emerge. If dependent, then UV research in IBD will continue to forge ahead in the context of vitamin D. In either case, an individual-level study of UV exposure and IBD activity, as well as clarification of causal mechanisms including vitamin D levels, can be done in parallel and is beneficial to the advancement of this burgeoning area of research.