Round-the-clock performance of coronary CT angiography for suspected acute coronary syndrome: Results from the BEACON trial

AbstractObjectiveTo assess the image quality of coronary CT angiography (CCTA) for suspected acute coronary syndrome (ACS) outside office hours.MethodsPatients with symptoms suggestive of an ACS underwent CCTA at the emergency department 24 hours, 7 days a week. A total of 118 patients, of whom 89 (75 %) presented during office hours (weekdays between 07:00 and 17:00) and 29 (25 %) outside office hours (weekdays between 17:00 and 07:00, weekends and holidays) underwent CCTA. Image quality was evaluated per coronary segment by two experienced readers and graded on an ordinal scale ranging from 1 to 3.ResultsThere were no significant differences in acquisition parameters, beta-blocker administration or heart rate between patients presenting during office hours and outside office hours. The median quality score per patient was 30.5 [interquartile range 26.0–33.5] for patients presenting during office hours in comparison to 27.5 [19.75–32.0] for patients presenting outside office hours (p=0.043). The number of non-evaluable segments was lower for patients presenting during office hours (0 [0–1.0] vs. 1.0 [0–4.0], p=0.009).ConclusionImage quality of CCTA outside office hours in the diagnosis of suspected ACS is diminished.Key Points• Quality scores were higher for coronary-CTA during office hours. • There were no differences in acquisition parameters. • There was a non-significant trend towards higher heart rates outside office hours. • Coronary-CTA on the ED requires state-of-the-art scanner technology and sufficiently trained staff. • Coronary-CTA on the ED needs preparation time and optimisation of the procedure.

[1]  H. Krumholz,et al.  Relationship between time of day, day of week, timeliness of reperfusion, and in-hospital mortality for patients with acute ST-segment elevation myocardial infarction. , 2005, JAMA.

[2]  Relationship between time of day, day of week, timeliness of reperfusion, and in-hospital mortality for patients with acute ST-segment elevation myocardial infarction. , 2005 .

[3]  I. Palacios,et al.  Impact of Time of Presentation on the Care and Outcomes of Acute Myocardial Infarction , 2008, Circulation.

[4]  R. Morin,et al.  Ionizing Radiation in Cardiac Imaging: A Science Advisory From the American Heart Association Committee on Cardiac Imaging of the Council on Clinical Cardiology and Committee on Cardiovascular Imaging and Intervention of the Council on Cardiovascular Radiology and Intervention , 2009, Circulation.

[5]  James McCord,et al.  Testing of low-risk patients presenting to the emergency department with chest pain: a scientific statement from the American Heart Association. , 2010, Circulation.

[6]  D. Berman,et al.  The CT-STAT (Coronary Computed Tomographic Angiography for Systematic Triage of Acute Chest Pain Patients to Treatment) trial. , 2011, Journal of the American College of Cardiology.

[7]  C. Gatsonis,et al.  CT angiography for safe discharge of patients with possible acute coronary syndromes. , 2012, The New England journal of medicine.

[8]  J. Fleg,et al.  Coronary CT angiography versus standard evaluation in acute chest pain. , 2012, The New England journal of medicine.

[9]  U. Schoepf,et al.  Expert opinion: Is 24/7 coverage necessary for implementing coronary CT angiography in the emergency room setting? , 2013, Journal of thoracic imaging.

[10]  R. Cury,et al.  Triage of patients presenting with chest pain to the emergency department: implementation of coronary CT angiography in a large urban health care system. , 2013, AJR. American journal of roentgenology.

[11]  K. Chinnaiyan,et al.  SCCT guidelines on the use of coronary computed tomographic angiography for patients presenting with acute chest pain to the emergency department: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee. , 2014, Journal of cardiovascular computed tomography.

[12]  H. Nathoe,et al.  Coronary CT Angiography for Suspected ACS in the Era of High-Sensitivity Troponins: Randomized Multicenter Study. , 2016, Journal of the American College of Cardiology.

[13]  Jeffrey L. Greenwald,et al.  Clinical implementation of an emergency department coronary computed tomographic angiography protocol for triage of patients with suspected acute coronary syndrome , 2017, European Radiology.