Current sample handling methods for measurement of platinum-DNA adducts in leucocytes in man lead to discrepant results in DNA adduct levels and DNA repair.

[1]  F. Perera,et al.  Platinum‐DNA adducts assayed in leukocytes of patients with germ cell tumors measured by atomic absorbance spectrometry and enzyme‐linked immunosorbent assay , 1994, Cancer.

[2]  J. Verweij,et al.  Pharmacokinetic-dynamic relationship of cisplatin in vitro: simulation of an i.v. bolus and 3 h and 20 h infusion. , 1994, British Journal of Cancer.

[3]  R. Tarone,et al.  Platinum-DNA adduct in leukocyte DNA of a cohort of 49 patients with 24 different types of malignancies. , 1993, Cancer research.

[4]  R. Tarone,et al.  Platinum drug-DNA interactions in human tissues measured by cisplatin-DNA enzyme-linked immunosorbent assay and atomic absorbance spectroscopy. , 1993, Environmental health perspectives.

[5]  R. Tarone,et al.  Platinum-DNA damage in leukocyte DNA of patients receiving carboplatin and cisplatin chemotherapy, measured by atomic absorption spectrometry. , 1991, Carcinogenesis.

[6]  R. Baan,et al.  Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: comparison with in vitro adduct formation. , 1990, Cancer research.

[7]  S. Steinberg,et al.  Evaluation of platinum-DNA adduct levels relative to known prognostic variables in a cohort of ovarian cancer patients. , 1990, Cancer research.

[8]  R. Baan,et al.  Influence of the degree of DNA modification on the immunochemical determination of cisplatin-DNA adduct levels. , 1989, Carcinogenesis.

[9]  P. Steerenberg,et al.  Platinum concentrations and DNA adduct levels in tumors and organs of cisplatin-treated LOU/M rats inoculated with cisplatin-sensitive or -resistant immunoglobulin M immunocytoma. , 1989, Cancer research.

[10]  Shirley A. Miller,et al.  A simple salting out procedure for extracting DNA from human nucleated cells. , 1988, Nucleic acids research.

[11]  R. Tarone,et al.  Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[12]  A. V. van Oosterom,et al.  cis-Diamminedichloroplatinum(II)-induced DNA adducts in peripheral leukocytes from seven cancer patients: quantitative immunochemical detection of the adduct induction and removal after a single dose of cis-diamminedichloroplatinum(II). , 1987, Cancer research.

[13]  S. Yuspa,et al.  cis-Diamminedichloroplatinum (II)-DNA adduct formation in renal, gonadal, and tumor tissues of male and female rats. , 1987, Cancer research.

[14]  H. Pinedo,et al.  Pharmacokinetics of free platinum species following rapid, 3-hr and 24-hr infusions of cis-diamminedichloroplatinum (II) and its therapeutic implications. , 1982, European journal of cancer & clinical oncology.

[15]  K. Kirby [98] Isolation of nucleic acids with phenolic solvents , 1968 .