Swallowing and speech ability after treatment for head and neck cancer with targeted intraarterial versus intravenous chemoradiation

RADPLAT (concurrent selective supradose intraarterial cisplatin and external‐beam irradiation) delivers extraordinarily high cisplatin concentration to head and neck structures. This study was designed to quantify and compare RADPLAT and systemic chemoradiation treatment effects on swallowing and speech.

[1]  A. Rademaker,et al.  Oropharyngeal swallow efficiency as a representative measure of swallowing function. , 1994, Journal of speech and hearing research.

[2]  T. Murry,et al.  A novel organ preservation protocol for advanced carcinoma of the larynx and pharynx. , 1996, Archives of otolaryngology--head & neck surgery.

[3]  Jo Shapiro,et al.  Evaluation and treatment of swallowing disorders , 1992, Comprehensive therapy.

[4]  P. Kahrilas,et al.  The benefit of head rotation on pharyngoesophageal dysphagia. , 1989, Archives of physical medicine and rehabilitation.

[5]  C. Lazarus,et al.  Swallowing Disorders in Head and Neck Cancer Patients Treated With Radiotherapy and Adjuvant Chemotherapy , 1996, The Laryngoscope.

[6]  A. Rademaker,et al.  Pretreatment swallowing function in patients with head and neck cancer , 2000, Head & neck.

[7]  Karl J. Friston,et al.  Variance Components , 2003 .

[8]  S. Howell,et al.  A targeted supradose cisplatin chemoradiation protocol for advanced head and neck cancer. , 1994, American journal of surgery.

[9]  J. Logemann,et al.  Manual for the videofluorographic study of swallowing , 1986 .

[10]  J. Logemann.  Swallowing physiology and pathophysiology. , 1988, Otolaryngologic clinics of North America.

[11]  T. Murry,et al.  Eating and weight changes following chemoradiation therapy for advanced head and neck cancer. , 1998, Archives of otolaryngology--head & neck surgery.

[12]  K. Robbins,et al.  Concomitant radiation therapy and targeted cisplatin chemotherapy for the treatment of advanced pyriform sinus carcinoma: Disease control and preservation of organ function , 1999, Head & neck.

[13]  K. Robbins,et al.  Targeted chemoradiation for advanced head and neck cancer: Analysis of 213 patients , 2000, Head & neck.