Genetic Instability Markers in Cancer.

[1]  O. Schildgen,et al.  Microsatellite instability testing in colorectal cancer using the QiaXcel advanced platform , 2018, BMC Cancer.

[2]  F. Chang,et al.  Microsatellite Instability: A Predictive Biomarker for Cancer Immunotherapy , 2017, Applied immunohistochemistry & molecular morphology : AIMM.

[3]  Laurence Zitvogel,et al.  The immune contexture in cancer prognosis and treatment , 2017, Nature Reviews Clinical Oncology.

[4]  Cynthia J. Sakofsky,et al.  Break induced replication in eukaryotes: mechanisms, functions, and consequences , 2017, Critical reviews in biochemistry and molecular biology.

[5]  Levi Garraway,et al.  Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden , 2017, Genome Medicine.

[6]  Maria Colombino,et al.  Genetic instability and increased mutational load: which diagnostic tool best direct patients with cancer to immunotherapy? , 2017, Journal of Translational Medicine.

[7]  J. Guinney,et al.  Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer , 2017, Nature Reviews Cancer.

[8]  N. Jamieson,et al.  Gene expression profiling to predict responsiveness to immunotherapy , 2016, Cancer Gene Therapy.

[9]  James R. Eshleman,et al.  Microsatellite Instability as a Biomarker for PD-1 Blockade , 2016, Clinical Cancer Research.

[10]  C. E. Pearson,et al.  Disease-associated repeat instability and mismatch repair. , 2016, DNA repair.

[11]  K. Kinzler,et al.  The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints , 2015, Journal of Immunotherapy for Cancer.

[12]  Jeffrey S. Morris,et al.  The Consensus Molecular Subtypes of Colorectal Cancer , 2015, Nature Medicine.

[13]  S. Richman.  Deficient mismatch repair: Read all about it (Review) , 2015, International journal of oncology.

[14]  Bert Vogelstein,et al.  PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. , 2015, The New England journal of medicine.

[15]  G. Rancati,et al.  Aneuploidy and chromosomal instability in cancer: a jackpot to chaos , 2015, Cell Division.

[16]  A. Cossu,et al.  Impact of tissue type and content of neoplastic cells of samples on the quality of epidermal growth factor receptor mutation analysis among patients with lung adenocarcinoma , 2015, Molecular medicine reports.

[17]  Alexander M. Metcalf,et al.  Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks , 2014, eLife.

[18]  X. Matías-Guiu,et al.  Mismatch repair status and clinical outcome in endometrial cancer: a systematic review and meta-analysis. , 2013, Critical reviews in oncology/hematology.

[19]  Steven J. M. Jones,et al.  Comprehensive molecular characterization of human colon and rectal cancer , 2012, Nature.

[20]  N. Moatamed,et al.  The effect of delay in fixation, different fixatives, and duration of fixation in estrogen and progesterone receptor results in breast carcinoma. , 2011, American journal of clinical pathology.

[21]  Heather Hampel,et al.  Feasibility of screening for Lynch syndrome among patients with colorectal cancer. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[22]  J. Shia.  Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part I. The utility of immunohistochemistry. , 2008, The Journal of molecular diagnostics : JMD.

[23]  M. Andreu,et al.  Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer. , 2005, JAMA.

[24]  G. Botti,et al.  Microsatellite instability in melanocytic skin lesions (benign nevi, dysplastic nevi, and primari melanomas along with their metastases , 2004 .

[25]  G. Botti,et al.  Microsatellite instability and mutation analysis among southern Italian patients with colorectal carcinoma: detection of different alterations accounting for MLH1 and MSH2 inactivation in familial cases. , 2003, Annals of oncology : official journal of the European Society for Medical Oncology.

[26]  G. Botti,et al.  Assessment of genetic instability in melanocytic skin lesions through microsatellite analysis of benign naevi, dysplastic naevi, and primary melanomas and their metastases , 2003, Melanoma research.

[27]  A. Cossu,et al.  Chromosomal abnormalities and microsatellite instability in sporadic endometrial cancer. , 2002, European journal of cancer.

[28]  A. Cossu,et al.  Prevalence and prognostic role of microsatellite instability in patients with rectal carcinoma. , 2002, Annals of oncology : official journal of the European Society for Medical Oncology.

[29]  C. Schlötterer.  Evolutionary dynamics of microsatellite DNA , 2000, Chromosoma.

[30]  J. Jurka,et al.  Microsatellites in different eukaryotic genomes: survey and analysis. , 2000, Genome research.

[31]  M. Jasin.  Chromosome Breaks and Genomic Instability , 2000, Cancer investigation.

[32]  F. Pontén,et al.  A high frequency of sequence alterations is due to formalin fixation of archival specimens. , 1999, The American journal of pathology.

[33]  K. Kinzler,et al.  Genetic instabilities in human cancers , 1998, Nature.

[34]  N. Pandis,et al.  Near-diploid karyotypes with recurrent chromosome abnormalities characterize early-stage endometrial cancer. , 1995, Cancer genetics and cytogenetics.

[35]  R. Richards,et al.  Dynamic mutations: where are they now? , 2012, Advances in experimental medicine and biology.

[36]  S. Thibodeau,et al.  EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome , 2009, Genetics in Medicine.

[37]  Copyright © American Society for Investigative Pathology Review Effect of Fixatives and Tissue Processing on the Content and Integrity of Nucleic Acids , 2022 .