Articular cartilage and growth plate defects are associated with chondrocyte cytoskeletal abnormalities in Tg737orpk mice lacking the primary cilia protein polaris.
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B. Yoder | C. Haycraft | S. McGlashan | C. Jensen | C. Poole
[1] S. McGlashan,et al. Localization of Extracellular Matrix Receptors on the Chondrocyte Primary Cilium , 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[2] Johan Ericson,et al. Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. , 2005, Developmental biology.
[3] Peter Satir,et al. PDGFRαα Signaling Is Regulated through the Primary Cilium in Fibroblasts , 2005, Current Biology.
[4] Didier Y. R. Stainier,et al. Vertebrate Smoothened functions at the primary cilium , 2005, Nature.
[5] Qihong Zhang,et al. Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function , 2005, PLoS genetics.
[6] Véronique Lefebvre,et al. Transcriptional control of chondrocyte fate and differentiation. , 2005, Birth defects research. Part C, Embryo today : reviews.
[7] F. Beier,et al. Rac1/Cdc42 and RhoA GTPases Antagonistically Regulate Chondrocyte Proliferation, Hypertrophy, and Apoptosis , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[8] F. Beier,et al. RhoA/ROCK Signaling Regulates Sox9 Expression and Actin Organization during Chondrogenesis* , 2005, Journal of Biological Chemistry.
[9] E. Schipani,et al. Molecular mechanisms of endochondral bone development. , 2005, Biochemical and biophysical research communications.
[10] Bethan E. Hoskins,et al. Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse , 2004, Nature Genetics.
[11] G. Pazour,et al. orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization , 2004, Development.
[12] Bethan E. Hoskins,et al. The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression , 2004, Nature Genetics.
[13] F. Beier,et al. RhoA/ROCK Signaling Suppresses Hypertrophic Chondrocyte Differentiation* , 2004, Journal of Biological Chemistry.
[14] V. Lefebvre,et al. Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate , 2004, The Journal of cell biology.
[15] Ilyas M. Khan,et al. The surface of articular cartilage contains a progenitor cell population , 2004, Journal of Cell Science.
[16] S. Bowser,et al. Ultrastructural, tomographic and confocal imaging of the chondrocyte primary cilium in situ , 2004, Cell biology international.
[17] H. Gruber,et al. Alterations in growth plate and articular cartilage morphology are associated with reduced SOX9 localization in the magnesium-deficient rat , 2004, Biotechnic & histochemistry : official publication of the Biological Stain Commission.
[18] Lee Niswander,et al. Hedgehog signalling in the mouse requires intraflagellar transport proteins , 2003, Nature.
[19] S. V. Webster,et al. The distribution of Notch receptors and their ligands during articular cartilage development , 2003, Journal of anatomy.
[20] A. Pitsillides,et al. A mechanism underlying the movement requirement for synovial joint cavitation. , 2003, Matrix biology : journal of the International Society for Matrix Biology.
[21] H. Kronenberg,et al. Developmental regulation of the growth plate , 2003, Nature.
[22] C. Archer,et al. Development of synovial joints. , 2003, Birth defects research. Part C, Embryo today : reviews.
[23] Qihong Zhang,et al. Loss of the Tg737 protein results in skeletal patterning defects , 2003, Developmental dynamics : an official publication of the American Association of Anatomists.
[24] D. Ingber. Tensegrity I. Cell structure and hierarchical systems biology , 2003, Journal of Cell Science.
[25] G. Pazour,et al. The vertebrate primary cilium is a sensory organelle. , 2003, Current opinion in cell biology.
[26] L. Guay-Woodford,et al. The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. , 2002, Journal of the American Society of Nephrology : JASN.
[27] C. Bugg,et al. Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium. , 2002, American journal of physiology. Renal physiology.
[28] A. McMahon,et al. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. , 2001, Development.
[29] C. A. Poole,et al. The differential distribution of acetylated and detyrosinated alpha‐tubulin in the microtubular cytoskeleton and primary cilia of hyaline cartilage chondrocytes , 2001, Journal of anatomy.
[30] C. Archer,et al. The development of articular cartilage: evidence for an appositional growth mechanism , 2001, Anatomy and Embryology.
[31] J. Thomas,et al. The C. elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms. , 2001, Development.
[32] B. Yoder,et al. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. , 2001, Molecular biology of the cell.
[33] U. Aebi,et al. The Chondrocyte Cytoskeleton in Mature Articular Cartilage: Structure and Distribution of Actin, Tubulin, and Vimentin Filaments , 2000, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[34] Dan L. Bader,et al. Confocal Analysis of Cytoskeletal Organisation within Isolated Chondrocyte Sub-populations Cultured in Agarose , 2000, The Histochemical Journal.
[35] C. Farquharson,et al. Microtubules are potential regulators of growth-plate chondrocyte differentiation and hypertrophy. , 1999, Bone.
[36] E. Hunziker,et al. Hypertrophy of growth plate chondrocytes in vivo is accompanied by modulations in the activity state and surface area of their cytoplasmic organelles , 1999, Histochemistry and Cell Biology.
[37] V. Trinkaus-Randall,et al. Chondrocyte survival and differentiation in situ are integrin mediated , 1997, Developmental dynamics : an official publication of the American Association of Anatomists.
[38] D. Wheatley,et al. CONFOCAL ANALYSIS OF PRIMARY CILIA STRUCTURE AND COLOCALIZATION WITH THE GOLGI APPARATUS IN CHONDROCYTES AND AORTIC SMOOTH MUSCLE CELLS , 1997, Cell biology international.
[39] D. Ingber,et al. Integrins, tensegrity, and mechanotransduction. , 1997, Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology.
[40] Jeffrey H. Price,et al. Video microscopy to quantitate the inhomogeneous equilibrium strain within articular cartilage during confined compression , 1996, Annals of Biomedical Engineering.
[41] R. Killiany,et al. Increased cell diameter precedes chondrocyte terminal differentiation, whereas cell‐matrix attachment complex proteins appear constant , 1996, The Anatomical record.
[42] E. Hunziker. Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes , 1994, Microscopy research and technique.
[43] J. Ralphs,et al. Cytoskeleton of cartilage cells , 1994, Microscopy research and technique.
[44] W E Sweeney,et al. Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. , 1994, Science.
[45] P. Eggli,et al. Quantitation of structural features characterizing weight‐ and less‐weight‐bearing regions in articular cartilage: A stereological analysis of medical femoral condyles in young adult rabbits , 1988, The Anatomical record.
[46] P. Benya,et al. Alterations in chondrocyte cytoskeletal architecture during phenotypic modulation by retinoic acid and dihydrocytochalasin B-induced reexpression , 1988, The Journal of cell biology.
[47] P. Benya,et al. Microfilament modification by dihydrocytochalasin B causes retinoic acid-modulated chondrocytes to reexpress the differentiated collagen phenotype without a change in shape , 1988, The Journal of cell biology.
[48] K.,et al. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. , 1987, The Journal of bone and joint surgery. American volume.
[49] E. Hunziker,et al. The role of hypertrophic chondrocytes in endochondral ossification and in the development of secondary centers of ossification. , 1987, The Journal of bone and joint surgery. American volume.
[50] C. Farnum,et al. Incidence and morphology of equine and murine chondrocytic cilia , 1980, The Anatomical record.
[51] N. Wilsman. Numerical density of convex, nonbranching organelles in anisotropically oriented cells. Cilia in tangential chondrocytes. , 1979, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[52] C. Rieder,et al. The occurrence and structure of primary cilia in a subline of Potorous tridactylus. , 1979, Experimental cell research.
[53] N. Wilsman. Cilia of adult canine articular chondrocytes. , 1978, Journal of ultrastructure research.
[54] N. Wilsman,et al. Cilia of neonatal articular chondrocytes incidence and morphology , 1978, The Anatomical record.
[55] G E Kempson,et al. The tensile properties of the cartilage of human femoral condyles related to the content of collagen and glycosaminoglycans. , 1973, Biochimica et biophysica acta.
[56] B. Yoder,et al. Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737orpk mutant mice , 2005, Laboratory Investigation.
[57] John F. Bolton,et al. Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels. , 2000, Journal of biomechanics.
[58] D E Ingber,et al. Tensegrity and mechanoregulation: from skeleton to cytoskeleton. , 1999, Osteoarthritis and cartilage.
[59] C. Rieder,et al. Primary cilia cycle in PtK1 cells: effects of colcemid and taxol on cilia formation and resorption. , 1987, Cell motility and the cytoskeleton.
[60] C A Poole,et al. Analysis of the morphology and function of primary cilia in connective tissues: a cellular cybernetic probe? , 1985, Cell motility.