Transcriptome Sequence of the Bloodstream Form of Trypanoplasma borreli, a Hematozoic Parasite of Fish Transmitted by Leeches

ABSTRACT Here, we report a transcriptome sequence of Trypanoplasma borreli isolated from its natural host, the common carp, Cyprinus carpio. The transcriptome allows an analysis of abundant cell surface proteins and acts as a comparator for understanding the evolution and pathogenicity of other Kinetoplastida, including several that infect humans.

[1]  S. Kelly,et al.  OrthoFinder: solving fundamental biases in whole genome comparisons dramatically improves orthogroup inference accuracy , 2015, Genome Biology.

[2]  C. S. Sutherland,et al.  A Literature Review of Economic Evaluations for a Neglected Tropical Disease: Human African Trypanosomiasis (“Sleeping Sickness”) , 2015, PLoS neglected tropical diseases.

[3]  Alexandre Lomsadze,et al.  Identification of protein coding regions in RNA transcripts , 2014, BCB.

[4]  W. Pirovano,et al.  SSPACE-LongRead: scaffolding bacterial draft genomes using long read sequence information , 2014, BMC Bioinformatics.

[5]  R. Durbin,et al.  Efficient de novo assembly of large genomes using compressed data structures. , 2012, Genome research.

[6]  J. Stevens,et al.  Resolving the question of trypanosome monophyly: a comparative genomics approach using whole genome data sets with low taxon sampling. , 2011, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

[7]  A. Simpson,et al.  The evolution and diversity of kinetoplastid flagellates. , 2006, Trends in parasitology.

[8]  S. Adl,et al.  The New Higher Level Classification of Eukaryotes with Emphasis on the Taxonomy of Protists , 2005, The Journal of eukaryotic microbiology.

[9]  J. Saeij,et al.  The immune response of carp to Trypanoplasma borreli: kinetics of immune gene expression and polyclonal lymphocyte activation. , 2003, Developmental and comparative immunology.

[10]  S. Poynton,et al.  A novel trypanoplasm-like flagellate Jarrellia atramenti n. g., n. sp. (Kinetoplastida: Bodonidae) and ciliates from the blowhole of a stranded pygmy sperm whale Kogia breviceps (Physeteridae): morphology, life cycle and potential pathogenicity. , 2001, Diseases of aquatic organisms.

[11]  D. Steinhagen,et al.  The parasitemia of cloned Trypanoplasma borreli Laveran and Mesnil, 1901, in laboratory-infected common carp (Cyprinus carpio L.). , 1989, The Journal of parasitology.

[12]  D. Steinhagen,et al.  Morphometries and Redescription of Trypanoplasma borreli Laveran & Mesnil, 1901 (Mastigophora, Kinetoplastida) from Experimentally Infected Common Carp (Cyprinus carpio L.) , 1989 .