Multi-subcarrier system with multiple numerologies

A method of operating a wireless communication device or a radio access node comprises addressing multi-subcarrier system resources using at least one of multiple different numerologies available within a single carrier, wherein the multiple different numerologies comprise a first numerology having resource blocks with a first bandwidth and a first subcarrier spacing, DELTAf1, and a second numerology having RBs with a second bandwidth and a second subcarrier spacing, DELTAf2, which is different from DELTAf1, and wherein the first numerology is aligned in the frequency domain relative to a frequency reference, Fref, according to m*DELTAf1 + Fref and the second numerology is aligned in the frequency domain relative to the frequency reference, Fref, according to n*DELTAf2 + Fref, where m andn are integers. The method further comprises transmitting and/or receiving information within the single carrier according to the at least one of the multiple different numerologies.