patterning provide context and positional information in Shh-directed neural Neural-specific Sox 2 input and differential Gli-binding affinity
暂无分享,去创建一个
T. Mikkelsen | A. Oudenaarden | W. Wong | M. Bulyk | A. McMahon | B. Bernstein | T. Bailey | Wenxiu Ma | Anastasia Vedenko | J. Junker | Leila Shokri | Xiaoxiao Zhang | Kevin A. Peterson | Y. Nishi | José-Manuel Baizabal | Matthew R McFarlane | W. Wong
[1] J. Ericson,et al. Mechanistic differences in the transcriptional interpretation of local and long-range Shh morphogen signaling. , 2012, Developmental cell.
[2] Johan Ericson,et al. Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors , 2012, Development.
[3] Raymond K. Auerbach,et al. An Integrated Encyclopedia of DNA Elements in the Human Genome , 2012, Nature.
[4] A. McMahon,et al. An embryonic stem cell‐based system for rapid analysis of transcriptional enhancers , 2012, Genesis.
[5] James Briscoe,et al. Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube , 2012, Cell.
[6] R. Sandberg,et al. Sequentially acting Sox transcription factors in neural lineage development. , 2011, Genes & development.
[7] Hui Wang,et al. Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS , 2011, Development.
[8] A. McMahon,et al. Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function. , 2011, Developmental cell.
[9] Matt Thomson,et al. Pluripotency Factors in Embryonic Stem Cells Regulate Differentiation into Germ Layers , 2011, Cell.
[10] Andrea I. Ramos,et al. The cis-Regulatory Logic of Hedgehog Gradient Responses: Key Roles for Gli Binding Affinity, Competition, and Cooperativity , 2011, Science Signaling.
[11] E. Metzakopian,et al. Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity , 2011, Mechanisms of Development.
[12] Ryan A. Flynn,et al. A unique chromatin signature uncovers early developmental enhancers in humans , 2011, Nature.
[13] James Briscoe,et al. Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. , 2010, Genes & development.
[14] James Briscoe,et al. Dynamic Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by the Morphogen Sonic Hedgehog , 2010, PLoS biology.
[15] Martha L Bulyk,et al. Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity. , 2010, Genes & development.
[16] M. Berger,et al. Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors , 2009, Nature Protocols.
[17] Hongkai Ji,et al. A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb. , 2008, Genes & development.
[18] Scott A. Rifkin,et al. Imaging individual mRNA molecules using multiple singly labeled probes , 2008, Nature Methods.
[19] James Briscoe,et al. Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network , 2008, Development.
[20] A. McMahon,et al. Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning , 2008, Development.
[21] James Briscoe,et al. Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism , 2007, Nature.
[22] C. Fan,et al. Gas1 extends the range of hedgehog action by facilitating its signaling , 2007 .
[23] Andrew P. McMahon,et al. Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning , 2007, Development.
[24] Toyoaki Tenzen,et al. The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development. , 2007, Genes & development.
[25] A. Philippakis,et al. Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities , 2006, Nature Biotechnology.
[26] M. Matise,et al. Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube. , 2006, Developmental cell.
[27] Toyoaki Tenzen,et al. The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice. , 2006, Developmental cell.
[28] A. Joyner,et al. Sonic hedgehog Signaling Regulates Gli2 Transcriptional Activity by Suppressing Its Processing and Degradation , 2006, Molecular and Cellular Biology.
[29] E. Ukkonen,et al. Genome-wide Prediction of Mammalian Enhancers Based on Analysis of Transcription-Factor Binding Affinity , 2006, Cell.
[30] Yanyun Li,et al. Evidence for the direct involvement of βTrCP in Gli3 protein processing , 2006 .
[31] Dmitri Papatsenko,et al. Quantitative analysis of binding motifs mediating diverse spatial readouts of the Dorsal gradient in the Drosophila embryo. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[32] J. Briscoe,et al. The floor plate: multiple cells, multiple signals , 2005, Nature Reviews Neuroscience.
[33] L. Pevny,et al. SOX genes and neural progenitor identity , 2005, Current Opinion in Neurobiology.
[34] A. McMahon,et al. Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1 , 2004, Development.
[35] B. Novitch,et al. Vertebrate neurogenesis is counteracted by Sox1–3 activity , 2003, Nature Neuroscience.
[36] H. Wichterle,et al. A Requirement for Retinoic Acid-Mediated Transcriptional Activation in Ventral Neural Patterning and Motor Neuron Specification , 2003, Neuron.
[37] Kuniya Abe,et al. Identification of Cis-regulatory elements in the mouse Pax9/Nkx2-9 genomic region: implication for evolutionary conserved synteny. , 2003, Genetics.
[38] L. Pevny,et al. SOX2 Functions to Maintain Neural Progenitor Identity , 2003, Neuron.
[39] B. Oostra,et al. A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. , 2003, Human molecular genetics.
[40] A. McMahon,et al. A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord. , 2002, Genes & development.
[41] Jens Böse,et al. Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. , 2002, Genes & development.
[42] Jussi Taipale,et al. Small molecule modulation of Smoothened activity , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[43] H. Wichterle,et al. Directed Differentiation of Embryonic Stem Cells into Motor Neurons , 2002, Cell.
[44] S. Mango,et al. Regulation of Organogenesis by the Caenorhabditis elegans FoxA Protein PHA-4 , 2002, Science.
[45] T. Jessell,et al. Coordinate Regulation of Motor Neuron Subtype Identity and Pan-Neuronal Properties by the bHLH Repressor Olig2 , 2001, Neuron.
[46] A. McMahon,et al. The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides. , 2001, Developmental biology.
[47] T. Jessell. Neuronal specification in the spinal cord: inductive signals and transcriptional codes , 2000, Nature Reviews Genetics.
[48] T. Jessell,et al. A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube , 2000, Cell.
[49] Philip A Beachy,et al. Hedgehog-Regulated Processing of Gli3 Produces an Anterior/Posterior Repressor Gradient in the Developing Vertebrate Limb , 2000, Cell.
[50] A. Joyner,et al. Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms. , 1999, Development.
[51] A. Joyner,et al. Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. , 1998, Development.
[52] J. Rossant,et al. Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. , 1998, Development.
[53] M. Nakafuku,et al. A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. , 1997, Development.
[54] P. Beachy,et al. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function , 1996, Nature.
[55] M. Scott,et al. Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. , 1996, Genes & development.
[56] A. McMahon,et al. Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants , 1995, Nature.
[57] T. Jessell,et al. Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis , 1995, Cell.
[58] Michael Levine,et al. Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen , 1993, Cell.
[59] K. Kinzler,et al. The GLI gene encodes a nuclear protein which binds specific sequences in the human genome , 1990, Molecular and cellular biology.
[60] Martin Renqiang Min,et al. An integrated encyclopedia of DNA elements in the human genome , 2012 .
[61] W. Wong,et al. The analysis of ChIP-Seq data. , 2011, Methods in enzymology.
[62] A. Joyner,et al. All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3. , 2004, Developmental cell.