论文信息 - DoriC: a database of oriC regions in bacterial genomes

DoriC: a database of oriC regions in bacterial genomes

UNLABELLED Replication origins (oriCs) of bacterial genomes currently available in GenBank have been predicted by using a systematic method comprising the Z-curve analysis for nucleotide distribution asymmetry, DnaA box distribution, genes adjacent to candidate oriCs and phylogenetic relationships. These oriCs are organized into a MySQL database, DoriC, which provides extensive information and graphical views of the oriC regions. In addition, users can Blast a query sequence or even a whole genome against DoriC to find a homologous one. DoriC will be updated timely and the latest version is DoriC 1.8, in which oriCs of 425 genomes (468 chromosomes) are identified. AVAILABILITY DoriC can be accessed from http://tubic.tju.edu.cn/doric/. SUPPLEMENTARY INFORMATION Supplementary data are available at http://tubic.tju.edu.cn/doric/supplementary.htm.

Feng Gao | Chun-Ting Zhang | F. Gao | Chun-Ting Zhang

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