An RNA interference screen identifies metabolic regulators NR1D1 and PBP as novel survival factors for breast cancer cells with the ERBB2 signature.
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Ritu Jain | M. Brosnan | D. Conklin | M. Brosnan | C. Eifert | A. Kourtidis | Antonis Kourtidis | M Julia Brosnan | Cheryl Eifert | Richard D Carkner | Douglas S Conklin | R. Jain | Richard D. Carkner
[1] P. Tan,et al. Immunohistochemical detection of Ki67 in breast cancer correlates with transcriptional regulation of genes related to apoptosis and cell death , 2005, Modern Pathology.
[2] M. Rao,et al. Isolation and Characterization of PBP, a Protein That Interacts with Peroxisome Proliferator-activated Receptor* , 1997, The Journal of Biological Chemistry.
[3] T. Scholz,et al. Metabolic adaptation of the hypertrophied heart: role of the malate/aspartate and alpha-glycerophosphate shuttles. , 2000, Journal of molecular and cellular cardiology.
[4] M. Polymeropoulos,et al. Gene expression profiling detects gene amplification and differentiates tumor types in breast cancer. , 2003, Cancer research.
[5] J. Ross,et al. The HER‐2/neu Oncogene in Breast Cancer: Prognostic Factor, Predictive Factor, and Target for Therapy , 1998, Stem cells.
[6] R. Espinosa,et al. Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[7] Jayanta Debnath,et al. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. , 2003, Methods.
[8] Patrick J. Paddison,et al. Second-generation shRNA libraries covering the mouse and human genomes , 2005, Nature Genetics.
[9] Daohai Zhang,et al. Proteomic Study Reveals That Proteins Involved in Metabolic and Detoxification Pathways Are Highly Expressed in HER-2/neu-positive Breast Cancer* , 2005, Molecular & Cellular Proteomics.
[10] S. Ménard,et al. HER2 as a Prognostic Factor in Breast Cancer , 2001, Oncology.
[11] S. Mandrup,et al. The Orphan Nuclear Receptor Rev-Erbα Is a Peroxisome Proliferator-activated Receptor (PPAR) γ Target Gene and Promotes PPARγ-induced Adipocyte Differentiation* , 2003, Journal of Biological Chemistry.
[12] Youngsoo Kim,et al. Identification of novel PPARgamma target genes in primary human adipocytes. , 2006, Gene.
[13] Wen-Lin Kuo,et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. , 2006, Cancer cell.
[14] D. Conklin,et al. RNAi applications in target validation. , 2007, Ernst Schering Research Foundation workshop.
[15] Allison Jones,et al. cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells , 2003, Oncogene.
[16] Stefano Iacobelli,et al. Effects of light and food schedules on liver and tumor molecular clocks in mice. , 2005, Journal of the National Cancer Institute.
[17] C. Fontaine,et al. The role of the orphan nuclear receptor Rev-Erbα in adipocyte differentiation and function , 2005 .
[18] L. Chin,et al. A Genetic Screen for Candidate Tumor Suppressors Identifies REST , 2005, Cell.
[19] J. Engelman,et al. Constitutively Active Mitogen-activated Protein Kinase Kinase 6 (MKK6) or Salicylate Induces Spontaneous 3T3-L1 Adipogenesis* , 1999, The Journal of Biological Chemistry.
[20] Lyndsay N Harris,et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[21] Ajay N. Jain,et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. , 2006, Cancer cell.
[22] J. Folch,et al. A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.
[23] J. Menéndez,et al. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis , 2007, Nature Reviews Cancer.
[24] Y. Yarden,et al. Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.
[25] J. Pollack,et al. RNA interference‐based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes , 2006, Genes, chromosomes & cancer.
[26] Daniel Birnbaum,et al. Identification and validation of an ERBB2 gene expression signature in breast cancers , 2004, Oncogene.
[27] Christian A. Rees,et al. Molecular portraits of human breast tumours , 2000, Nature.
[28] R. Deberardinis,et al. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. , 2008, Cell metabolism.
[29] M. Brosnan,et al. Peroxisome proliferator-activated receptor-γ protects ERBB2-positive breast cancer cells from palmitate toxicity , 2009, Breast Cancer Research.
[30] J. Ramser,et al. Identification of brain- and bone-specific breast cancer metastasis genes. , 2009, Cancer letters.
[31] Ueli Schibler,et al. REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis , 2009, PLoS biology.
[32] P. Kauraniemi,et al. Activation of multiple cancer-associated genes at the ERBB2 amplicon in breast cancer. , 2006, Endocrine-related cancer.
[33] J. Gingrich,et al. Oxidative stress is the new stress , 2005, Nature Medicine.
[34] G. Muscat,et al. The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation? , 2006, Nuclear receptor signaling.
[35] M. Prentki,et al. A Role for ATP-Citrate Lyase, Malic Enzyme, and Pyruvate/Citrate Cycling in Glucose-induced Insulin Secretion* , 2007, Journal of Biological Chemistry.
[36] Patrick J. Paddison,et al. A resource for large-scale RNA-interference-based screens in mammals , 2004, Nature.
[37] S. Edlbacher,et al. Über den Stoffwechsel der Tumoren. IV. Mitteilung. , 2022 .
[38] H. Brentani,et al. Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma , 2008, Breast Cancer Research.
[39] S. Fox,et al. The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy , 2009, British Journal of Cancer.
[40] A Howell,et al. TPD52 and NFKB1 gene expression levels correlate with G2 chromosomal radiosensitivity in lymphocytes of women with and at risk of hereditary breast cancer , 2007, International journal of radiation biology.