Coagulopathy, Hypothermia and Acidosis in Trauma Patients: the Rationale for Damage Control Surgery

Abstract Severe trauma to the torso or extremities often results in significant hemorraghe, which contributes to morbidity and mortality. The pathophysiological mechanisms contributing to this traumatic blood loss are complex. We review its major components: coagulopathy, acidosis and hypothermia, which have led to the concept of damage control surgery.

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