Non-aggregated boron–fluorine derivatives with photodynamic activity

Novel non-aggregated boron–fluorine derivatives with large Stokes shift were facilely synthesized and characterized. These dyes show moderate absorptive coefficients and intense fluorescence emission, and excellent photo-stability in solvents and also in solid state. According to X-ray single-crystal analysis, non-covalent intermolecular interactions provide a rigid structure, which inhibits aggregate formation. These non-aggregated dyes can generate singlet oxygen under light irradiation, which makes them good candidates for photodynamic therapy. Copyright © 2012 John Wiley & Sons, Ltd.

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