Toxoplasma antibody titers by ELISA and indirect latex agglutination test in pregnant women.

The seroepidemiologic studies on anti-Toxoplasma antibody titers were carried out using ELISA and indirect latex agglutination test. Among 899 sera prepared from pregnant women, 39 cases (4.3%) revealed positive reaction and 218 sera from middle school students showed 4 positive reaction (1.8%) by ELISA. By LAT (newly established by National Veterinary Research Institute. Korea), the sera of 7 pregnant women (0.8%) showed positive reaction. When 80 sera showing > or = 1:8 by LAT were used for comparing the results obtained from LAT and Toxotest-MT (Eiken Chemical Co., Japan), 7 cases and 8 sera were positive, respectively. All of 11 sera of proven toxoplasmosis patients showed positive reaction in both tests. Overall proportion of agreement between LAT kit and Toxotest-MT was 0.94 (kappa-index = 0.632, p < 0.011, and LAT was considered to be useful for the screening of toxoplasmosis.

[1]  W. Sohn,et al.  [Infection status of Tapes philippinarum collected from southern coastal areas of Korea with Parvatrema spp. (Digenea:Gymnophallidae) metacercariae]. , 1996, The Korean journal of parasitology.

[2]  T. Yong,et al.  A carbohydrate antigen of Clonorchis sinensis recognized by a species-specific monoclonal antibody. , 1996, The Korean journal of parasitology.

[3]  Y. Kong,et al.  Detection of antibodies in serum and cerebrospinal fluid to Toxoplasma gondii by indirect latex agglutination test and enzyme-linked immunosorbent assay. , 1992, Kisaengch'unghak chapchi. The Korean journal of parasitology.

[4]  Y. Suzuki,et al.  Recognition of tachyzoite and bradyzoite antigens of Toxoplasma gondii by infected hosts , 1991, Infection and immunity.

[5]  J. Chatterton,et al.  Congenital toxoplasmosis - why and how to screen , 1990 .

[6]  A. Joss,et al.  Simultaneous serological screening for congenital cytomegalovirus and toxoplasma infection. , 1988, Public health.

[7]  K. Katakura,et al.  Toxoplasma antibodies by indirect latex agglutination tests in zoo animals. , 1987, Kisaengch'unghak chapchi. The Korean journal of parasitology.

[8]  J. Rha,et al.  [Significance of Toxoplasma antibody titers by indirect latex agglutination tests in pregnant women and pelvic tumor patients] , 1985, Kisaengch'unghak chapchi. The Korean journal of parasitology.

[9]  L. Kasper,et al.  Identification of stage-specific sporozoite antigens of Toxoplasma gondii by monoclonal antibodies. , 1984, Journal of immunology.

[10]  Sung-Nam Cho,et al.  [Toxoplasma Antibodies By Indirect Latex Agglutination Tests In National Seoul Mental Hospital Patients] , 1983, Kisaengch'unghak chapchi. The Korean journal of parasitology.

[11]  L. Jacobs,et al.  Antigenic differences between endozoites and cystozoites of Toxoplasma gondii. , 1983, The Journal of parasitology.

[12]  W. Y. Choi,et al.  [Toxoplasma antibodies by indirect latex agglutination tests in St. Mary's Hospital patients] , 1982, Kisaengch'unghak chapchi. The Korean journal of parasitology.

[13]  C. Wilson,et al.  Development of adverse sequelae in children born with subclinical congenital Toxoplasma infection. , 1980, Pediatrics.

[14]  P. Viens,et al.  Serological survey for congenital toxoplasmosis among 4,136 pregnant women. , 1977, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[15]  A. Bartlett,et al.  Enzyme immunoassays for parasitic diseases. , 1976, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[16]  J. Couvreur,et al.  Congenital toxoplasmosis. A prospective study of 378 pregnancies. , 1974, The New England journal of medicine.