Preparation and optical characterization of DNA-riboflavin thin films

Thin films of DNA biopolymer thin film are fabricated by a drop casting process on glass and silicon substrates, as well as freestanding. The refractive index is measured by elliposmetry and in bulk DNA film the refractive index is shown to be increased in the 600 to 900 nm DNA transparency window by doping with riboflavin. Further analysis with FT-IR, Raman, and XRD are used to determine whether binding between riboflavin and DNA occurs.

[1]  Jung-Il Jin,et al.  Materials science of DNA , 2011 .

[2]  Francois Kajzar,et al.  Optical Properties of Thin Films of DNA-CTMA and DNA-CTMA Doped with Nile Blue , 2012 .

[3]  E. Pun,et al.  Optical Amplification in Eu $^{3+}$-Doped DNA-Based Biopolymer , 2011, IEEE Photonics Technology Letters.

[4]  C. Borsarelli,et al.  Hydrogen-bonding modulation of excited-state properties of flavins in a model of aqueous confined environment. , 2012, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[5]  E FREDERICQ,et al.  The ultraviolet spectrum of deoxyribonucleic acids and their constituents. , 1961, Journal of molecular biology.

[6]  G. Lindblom,et al.  Electronic transitions in the isoalloxazine ring and orientation of flavins in model membranes studied by polarized light spectroscopy. , 1979, Biochemistry.

[7]  Naoya Ogata,et al.  Amplified Spontaneous Emission from Fluorescent‐Dye‐Doped DNA–Surfactant Complex Films , 2000 .

[8]  ANDREW J. STECKL,et al.  DNA – a new material for photonics? , 2007 .

[9]  James G. Grote,et al.  Optical properties of deoxyribonucleic acid (DNA) polymer host , 2006, SPIE Security + Defence.

[10]  Norio Nishi,et al.  Applied chemistry of natural DNA. , 2008, Chemical Society reviews.

[11]  Emily M. Heckman,et al.  Novel cationic dye and crosslinkable surfactant for DNA biophotonics , 2012, Other Conferences.

[12]  Naoya Ogata,et al.  Self-assembled supramolecular films derived from marine deoxyribonucleic acid (DNA)-cationic surfactant complexes : Large-scale preparation and optical and thermal properties , 2001 .

[13]  James G. Grote,et al.  Complex nonlinear refractive index of DNA , 2006 .

[14]  Sunghwan Kim,et al.  A fully biocompatible single-mode distributed feedback laser. , 2015, Lab on a chip.

[15]  Nithyaja Balan,et al.  Selective mode excitation in dye-doped DNA polyvinyl alcohol thin film. , 2009, Applied optics.

[16]  T. Dupont,et al.  Capillary flow as the cause of ring stains from dried liquid drops , 1997, Nature.

[17]  James G. Grote,et al.  On the Stability and Degradation of DNA Based Thin Films , 2010 .