CellsAssociation with Syk in Human B Chain Signals Through α The IL-15 R

[1]  L. Lanier,et al.  The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function. , 2000, Immunology today.

[2]  T. Waldmann,et al.  IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[3]  P. Musiani,et al.  The Combined Action of IL-15 and IL-12 Gene Transfer Can Induce Tumor Cell Rejection Without T and NK Cell Involvement1 , 2000, The Journal of Immunology.

[4]  K. Asadullah,et al.  Inhibition of Keratinocyte Apoptosis by IL-15: A New Parameter in the Pathogenesis of Psoriasis?1 , 2000, The Journal of Immunology.

[5]  S. Dubois,et al.  Subunit structure of the high and low affinity human interleukin-15 receptors. , 2000, European cytokine network.

[6]  T. Waldmann,et al.  Differences of biodistribution, pharmacokinetics, and tumor targeting between interleukins 2 and 15. , 2000, Cancer research.

[7]  J. D. Di Santo,et al.  Tyrosine kinase SYK: essential functions for immunoreceptor signalling. , 2000, Immunology today.

[8]  J. Shayman,et al.  Syk activation initiates downstream signaling events during human polymorphonuclear leukocyte phagocytosis. , 1999, Journal of immunology.

[9]  A. Weiss,et al.  Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression. , 1999, Journal of immunology.

[10]  R. Paus,et al.  Death deflected: IL‐15 inhibits TNF‐α‐mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL‐15Rα chain , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[11]  A. Waage,et al.  Interleukin‐15 blocks apoptosis and induces proliferation of the human myeloma cell line OH‐2 and freshly isolated myeloma cells , 1999, British journal of haematology.

[12]  M. Zucca,et al.  Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15. , 1999, Blood.

[13]  R. Gerstein,et al.  The role of cytokine receptor signaling in lymphocyte development. , 1999, Current opinion in immunology.

[14]  R. Abraham,et al.  Cutting edge: a role for the adaptor protein LAT in human NK cell-mediated cytotoxicity. , 1999, Journal of immunology.

[15]  P. Mayeux,et al.  Physical and Functional Interaction between p72 syk and Erythropoietin Receptor* , 1998, The Journal of Biological Chemistry.

[16]  J. Ihle,et al.  Signaling by the Cytokine Receptor Superfamily a , 1998, Annals of the New York Academy of Sciences.

[17]  T. Dassopoulos,et al.  IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. , 1998, Immunity.

[18]  Teruaki Kimura,et al.  Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity. , 1998, Journal of immunology.

[19]  W. Fiers,et al.  Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen. , 1998, Journal of immunology.

[20]  J. Satoh,et al.  Interleukin-15, a T-cell growth factor, is expressed in human neural cell lines and tissues , 1998, Journal of the Neurological Sciences.

[21]  R. Paus,et al.  Interleukin-15 protects from lethal apoptosis in vivo , 1997, Nature Medicine.

[22]  R. Zambello,et al.  Interleukin-15: a novel cytokine with regulatory properties on normal and neoplastic B lymphocytes. , 1997, Leukemia & lymphoma.

[23]  R. Paus,et al.  Differential regulation of human T lymphoblast functions by IL-2 and IL-15. , 1997, Cytokine.

[24]  T. Strom,et al.  Interleukin-15 signals T84 colonic epithelial cells in the absence of the interleukin-2 receptor beta-chain. , 1997, The American journal of physiology.

[25]  H. Kanegane,et al.  Interleukin-15 promotes angiogenesis in vivo. , 1997, Biochemical and biophysical research communications.

[26]  T. Pohl,et al.  Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms. , 1997, Journal of immunology.

[27]  M. Ueffing,et al.  Cloning and functional analysis of the hematopoietic cell‐specific phospholipase Cγ 2 promoter , 1996 .

[28]  P. Keely,et al.  The α2β1 Integrin Is a Necessary Co-receptor for Collagen-induced Activation of Syk and the Subsequent Phosphorylation of Phospholipase Cγ2 in Platelets* , 1996, The Journal of Biological Chemistry.

[29]  J. Kaptein,et al.  Anti-IgM-mediated Regulation of c-myc and Its Possible Relationship to Apoptosis* , 1996, The Journal of Biological Chemistry.

[30]  M. Matsuda,et al.  Abrogation of the Fc gamma receptor IIA-mediated phagocytic signal by stem-loop Syk antisense oligonucleotides. , 1996, Molecular biology of the cell.

[31]  N. Tanaka,et al.  Dispensability of Jak1 tyrosine kinase for interleukin‐2‐induced cell growth signaling in a human T cell line , 1996, European journal of immunology.

[32]  L. Lanier,et al.  Analysis of the costimulatory role of IL-2 and IL-15 in initiating proliferation of resting (CD56dim) human NK cells. , 1996, Journal of immunology.

[33]  G. Mills,et al.  Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils , 1996, The Journal of experimental medicine.

[34]  A. Sher,et al.  Induction and regulation of IL-15 expression in murine macrophages. , 1996, Journal of immunology.

[35]  N. Copeland,et al.  Functional Characterization of the Human Interleukin-15 Receptor αChain and Close Linkage of IL15RA and IL2RA Genes (*) , 1995, The Journal of Biological Chemistry.

[36]  R. Rees,et al.  Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[37]  A. Brunati,et al.  Site specificity of p72 syk protein tyrosine kinase: efficient phosphorylation of motifs recognized by Src homology 2 domains of the Src family , 1995, FEBS letters.

[38]  D. Cosman,et al.  IL‐15, a novel T cell growth factor that shares activities and receptor components with IL‐2 , 1995, Journal of leukocyte biology.

[39]  T. Taniguchi.  Cytokine signaling through nonreceptor protein tyrosine kinases. , 1995, Science.

[40]  R. Paxton,et al.  IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. , 1995, Journal of immunology.

[41]  B. Wilson,et al.  Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol. , 1994, The Journal of biological chemistry.

[42]  M. Caligiuri,et al.  Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor , 1994, The Journal of experimental medicine.

[43]  J. Kinet,et al.  The high-affinity receptor for immunoglobulin E. , 1994, Chemical immunology.

[44]  T. Waldmann,et al.  A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[45]  T. Waldmann,et al.  The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[46]  W. Leonard,et al.  The Molecular Basis of X‐Linked Severe Combined Immunodeficiency: The Role of the Interleukin‐2 Receptor γ Chain as a Common γ Chain, γc , 1994, Immunological reviews.

[47]  G. Kroemer,et al.  Signal Transduction Pathways Involved in B‐Cell Induction , 1993, Immunological reviews.

[48]  Y. Hannun,et al.  Programmed cell death induced by ceramide. , 1993, Science.

[49]  J. Bolen,et al.  The Src family of tyrosine protein kinases in hemopoietic signal transduction , 1992, Stem cells.

[50]  R. Perlmutter,et al.  Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association , 1991, Science.

[51]  M. Reth.  Antigen receptor tail clue , 1989, Nature.

[52]  R. Tsien,et al.  A new generation of Ca2+ indicators with greatly improved fluorescence properties. , 1985, The Journal of biological chemistry.

[53]  E. Jaffe,et al.  Mitogen requirements for the in vitro propagation of cutaneous T-cell lymphomas. , 1980, Blood.

[54]  T. Kurosaki,et al.  BLNK: connecting Syk and Btk to calcium signals. , 2000, Immunity.

[55]  T. Waldmann,et al.  The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. , 1999, Annual review of immunology.

[56]  W. Carson,et al.  Interleukin-15 as a potential regulator of the innate immune response. , 1998, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[57]  M. Reth,et al.  Initiation and processing of signals from the B cell antigen receptor. , 1997, Annual review of immunology.

[58]  黒木淳.  Cell-permeable ceramide inhibits the growth of B lymphoma Raji cells lacking TNF-α-receptors by inducing G0/G1 arrest but not apoptosis: a new model for dissecting cell-cycle arrest and apoptosis , 1996 .

[59]  T. Taniguchi,et al.  Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway. , 1995, Immunity.

[60]  J. Bolen,et al.  Interaction of p72 syk with the gand bSubunits of the High-Affinity Receptor for Immunoglobulin E, FcεRI , 1995 .

[61]  N. Tanaka,et al.  The Common γ-Chain for Multiple Cytokine Receptors , 1995 .

[62]  Phospholipase C- (cid:103) 1 Interacts with Conserved Phosphotyrosyl Residues in the Linker Region of Syk and Is a Substrate for Syk , 2022 .