A System for Analysis of Tremor in Patients with Parkinson's Disease Based on Motion Capture Technique

Resting tremor is one of the primary motor symptoms of Parkinson's Disease. In this paper we analyze the occurrence of tremor in Parkinson's disease by using a system for measurements of kinematic data of upper limbs. The experimental group includes seven PD patients during standing. Analysis is based on kinematic measurements done by using multimodal motion capture (MOCAP) system for registration of 3D positions of body markers, ground reaction forces and electromyography signals. All patients taking part in examination have undergone deep brain stimulation surgical treatment. Examination involved comparisons of tremor parameters across four conditions, where stimulator was turned ON/OFF and medication was ON/OFF. Obtained results confirm statistically significant differences of certain tremor parameters between different experimental conditions.

[1]  Giuliana Grimaldi,et al.  Neurological Tremor: Sensors, Signal Processing and Emerging Applications , 2010, Sensors.

[2]  L. Findley,et al.  Classification of tremors. , 1996, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[3]  Goutham Rao,et al.  Does this patient have Parkinson disease? , 2003, JAMA.

[4]  Elias S. Manolakos,et al.  Signal Background Estimation and Baseline Correction Algorithms for Accurate DNA Sequencing , 2003, J. VLSI Signal Process..

[5]  J. Jankovic,et al.  Physiologic and pathologic tremors. Diagnosis, mechanism, and management. , 1980, Annals of internal medicine.

[6]  M. Gelabert-González,et al.  [Deep brain stimulation in Parkinson's disease]. , 2013, Revista de neurologia.

[7]  A. Benabid.  Deep brain stimulation for Parkinson’s disease , 2003, Current Opinion in Neurobiology.