Investigating the mechanism for maintaining eucalcemia despite immobility and anuria in the hibernating American black bear (Ursus americanus).

[1]  F. Kainberger,et al.  Sclerostin serum levels correlate positively with bone mineral density and microarchitecture in haemodialysis patients. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[2]  A. Branscum,et al.  Sclerostin and Dickkopf-1 in renal osteodystrophy. , 2011, Clinical journal of the American Society of Nephrology : CJASN.

[3]  Dale M Edgar,et al.  Hibernation in Black Bears: Independence of Metabolic Suppression from Body Temperature , 2011, Science.

[4]  L. Bonewald,et al.  The Amazing Osteocyte , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[5]  L. Melton,et al.  Relation of Age, Gender, and Bone Mass to Circulating Sclerostin Levels in Women and Men , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[6]  Gerhard Hawa,et al.  Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss. , 2010, The Journal of clinical endocrinology and metabolism.

[7]  Guoyin Feng,et al.  Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β‐Catenin Signaling , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[8]  Kenji F. Tanaka,et al.  A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure , 2009, Cell.

[9]  M. Bouxsein,et al.  Serum IGF‐1 Determines Skeletal Strength by Regulating Subperiosteal Expansion and Trait Interactions , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[10]  S. Bloomfield,et al.  β‐Adrenergic Blockade and Leptin Replacement Effectively Mitigate Disuse Bone Loss , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[11]  B. Williams,et al.  Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone , 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[12]  K. Kaestner,et al.  The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity , 2008, The Journal of cell biology.

[13]  Miho Sato,et al.  Annual changes in serum leptin concentration in the adult female Japanese black bear (Ursus thibetanus japonicus). , 2008, The Journal of veterinary medical science.

[14]  M. Markel,et al.  Functional Adaptation to Loading of a Single Bone Is Neuronally Regulated and Involves Multiple Bones , 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[15]  C. Rubin,et al.  Functional Adaptation to Loading of a Single Bone Is Neuronally Regulated and Involves Multiple Bones , 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[16]  Matthew R Allen,et al.  Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/Sclerostin* , 2008, Journal of Biological Chemistry.

[17]  C. T. Robbins,et al.  Decreased bone turnover with balanced resorption and formation prevent cortical bone loss during disuse (hibernation) in grizzly bears (Ursus arctos horribilis). , 2008, Bone.

[18]  G. Karsenty.  CHAPTER 47 – Leptin-Dependent Regulation of Bone Mass , 2008 .

[19]  D. Bikle,et al.  CHAPTER 46 – Mechanisms of Immobilization-Induced Bone Loss , 2008 .

[20]  C. Rubin,et al.  CHAPTER 22 – Inhibition of Osteoporosis by Biophysical Intervention , 2008 .

[21]  S. Sprague,et al.  Role of Vitamin D Deficiency in Chronic Kidney Disease , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[22]  A. Arnold,et al.  Effects of anesthetic agents on serum parathyroid hormone and calcium concentrations in mice. , 2007, Veterinary anaesthesia and analgesia.

[23]  L. Lanyon,et al.  Wnt/β-Catenin Signaling Is a Component of Osteoblastic Bone Cell Early Responses to Load-bearing and Requires Estrogen Receptor α* , 2007, Journal of Biological Chemistry.

[24]  K. Clément,et al.  Cart overexpression is the only identifiable cause of high bone mass in melanocortin 4 receptor deficiency. , 2006, Endocrinology.

[25]  L. Demers,et al.  Parathyroid hormone may maintain bone formation in hibernating black bears (Ursus americanus) to prevent disuse osteoporosis , 2006, Journal of Experimental Biology.

[26]  Mary L Bouxsein,et al.  Mechanisms of Disease: is osteoporosis the obesity of bone? , 2006, Nature Clinical Practice Rheumatology.

[27]  Masaki Noda,et al.  Unloading Induces Osteoblastic Cell Suppression and Osteoclastic Cell Activation to Lead to Bone Loss via Sympathetic Nervous System* , 2005, Journal of Biological Chemistry.

[28]  Hans Clevers,et al.  Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. , 2005, Developmental cell.

[29]  Masaki Noda,et al.  Leptin regulation of bone resorption by the sympathetic nervous system and CART , 2005, Nature.

[30]  S. Donahue,et al.  Bending properties, porosity, and ash fraction of black bear (Ursus americanus) cortical bone are not compromised with aging despite annual periods of disuse. , 2004, Journal of biomechanics.

[31]  R. Zernicke,et al.  Maintenance of bone mass and architecture in denning black bears (Ursus americanus) , 2004 .

[32]  T. Phillips,et al.  Serum markers of bone metabolism show bone loss in hibernating bears. , 2004, Clinical orthopaedics and related research.

[33]  R. Eastell,et al.  Clinical performance of immunoreactive tartrate-resistant acid phosphatase isoform 5b as a marker of bone resorption. , 2004, Bone.

[34]  C. Marcelli,et al.  Sympathetic nervous system as transmitter of mechanical loading in bone. , 2003, Joint, bone, spine : revue du rhumatisme.

[35]  L. Demers,et al.  Bone formation is not impaired by hibernation (disuse) in black bears Ursus americanus , 2003, Journal of Experimental Biology.

[36]  B. Bergeron.  New Media, Medicine , 2003 .

[37]  S. Bonnick.  Bone Densitometry in Clinical Practice: Application and Interpretation , 2003 .

[38]  J. Zanchetta,et al.  Serum CrossLaps as Bone Resorption Marker in Peritoneal Dialysis , 2002, Peritoneal Dialysis International.

[39]  G. Stenhouse,et al.  A body-condition index for ursids , 2002 .

[40]  汪关煜.  Renal osteodystrophy , 2002 .

[41]  L. Lanyon,et al.  Perspective: Postmenopausal Osteoporosis as a Failure of Bone's Adaptation to Functional Loading: A Hypothesis * , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[42]  P. Iaizzo,et al.  Muscle strength in overwintering bears , 2001, Nature.

[43]  C. Rubin,et al.  Inhibition of Osteopenia by Biophysical Intervention , 2001 .

[44]  I Perkash,et al.  Bone mineral and geometric changes through the femur with immobilization due to spinal cord injury. , 2000, Journal of rehabilitation research and development.

[45]  J. Jones,et al.  The glyoxylate cycle: does it function in the dormant or active bear? , 1999, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[46]  J. Friedman,et al.  Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[47]  Roger P. Smith.  Osteoporosis: Diagnostic and therapeutic principles , 1997, European Journal of Clinical Nutrition.

[48]  S. Bonnick.  Bone Densitometry Techniques in Modern Medicine , 1996 .

[49]  J. Houde,et al.  Bone Mineral Density Changes in the Forearm After Immobilization , 1995, Clinical orthopaedics and related research.

[50]  L. Lanyon,et al.  Interruption of disuse by short duration walking exercise does not prevent bone loss in the sheep calcaneus. , 1995, Bone.

[51]  F. Abboud,et al.  Sympathetic-nerve activity during sleep in normal subjects. , 1993, The New England journal of medicine.

[52]  F. Coe,et al.  Disorders of bone and mineral metabolism , 1992 .

[53]  R. Nelson,et al.  Calcium and bone metabolic homeostasis in active and denning black bears (Ursus americanus). , 1990, Clinical orthopaedics and related research.

[54]  M. Caron,et al.  Precision and Accuracy of Estimating Age of Maine Black Bears by Cementum Annuli , 1990 .

[55]  D. V. Lindley,et al.  Applied nonparametric statistical methods , 1988 .

[56]  R. Nelson,et al.  BLOOD CHEMISTRY OF BLACK BEARS FROM PENNSYLVANIA DURING WINTER DORMANCY , 1988, Journal of wildlife diseases.

[57]  T. Beck,et al.  Ratio of serum urea to serum creatinine in wild black bears. , 1984, Science.

[58]  I. J. Singh,et al.  The effects of cold‐stress, hibernation, and prolonged inactivity on bone dynamics in the golden hamster, Mesocricetus auratus , 1981, Journal of morphology.

[59]  Z. Jaworski,et al.  Bone loss in response to long-term immobilisation. , 1978, The Journal of bone and joint surgery. British volume.

[60]  J. Whalen,et al.  A radiographic and histologic study of bone in the active and hibernating bat (Myotis lucifugus) , 1972, The Anatomical Record.

[61]  J M Vogel,et al.  Effect of prolonged bed rest on bone mineral. , 1970, Metabolism: clinical and experimental.