Application of photonic band gap fibers in capillary electrophoresis systems

In this paper we present a novel concept of using photonic band gap fibers for capillary electrophoresis (CE) in a configuration where both the analyzed solution and the light are fed through the hollow core of the fiber. The tested fiber was an HC19-1550-01 with 20 μm core size, manufactured by Blaze Photonics and rated for 1550 nm wavelength. Results of initial experiments in reflectometric and electrophoretic configurations are presented, opening up the possibility of developing a fiber-optic sensor based on CE for remote detection of targeted compounds. Such a sensor can be expected to have a wide temperature range of operation to excellent thermal stability of hollow-core PBG fibers.

[1]  Janusz Pawliszyn,et al.  Whole-column imaging-detection techniques and their analytical applications , 2005 .

[2]  Chun-Che Lin,et al.  Recent progress in pharmacokinetic applications of capillary electrophoresis , 2003, Electrophoresis.

[3]  Yafeng Guan,et al.  Light-emitting-diode-induced fluorescence detector for capillary electrophoresis using optical fiber with spherical end. , 2003, Talanta.

[4]  Emily F Hilder,et al.  Poly(tetrafluoroethylene) separation capillaries for capillary electrophoresis. Properties and applications. , 2004, Journal of chromatography. A.

[5]  Ewa Dabek-Zlotorzynska,et al.  Determination of hydroxymethanesulfonic acid in environmental samples by capillary electrophoresis , 2002 .

[6]  E. Lai,et al.  Determination of low-molecular-mass carboxylic acids in atmospheric aerosol and vehicle emission samples by capillary electrophoresis. , 2001, Journal of chromatography. A.

[7]  Janusz Pawliszyn,et al.  Whole‐column fluorescence‐imaged capillary electrophoresis , 2004, Electrophoresis.

[8]  Ewa Dabek-Zlotorzynska,et al.  Development and validation of capillary electrophoresis for the determination of selected metal ions in airborne particulate matter after sequential extraction , 2002, Analytical and bioanalytical chemistry.

[9]  Abdul Malik,et al.  Polymeric hollow fibers for capillary electrophoresis , 1993 .

[10]  Ewa Dabek‐Zlotorzynska,et al.  Recent advances in capillary electrophoresis and capillary electrochromatography of pollutants , 2003, Electrophoresis.

[11]  E Dabek-Zlotorzynska,et al.  Determination of dimethylamine and other low-molecular-mass amines using capillary electrophoresis with laser-induced fluorescence detection. , 1998, Journal of chromatography. B, Biomedical sciences and applications.

[12]  Günther K Bonn,et al.  Recent progress in high‐performance capillary bioseparations , 2003, Electrophoresis.

[13]  M J Sepaniak,et al.  Development of a new capillary electrophoresis-based fibre optic sensor. , 1997, Biomedical chromatography : BMC.

[14]  Yafeng Guan,et al.  A collinear light-emitting diode-induced fluorescence detector for capillary electrophoresis. , 2005, Talanta.

[15]  M J Sepaniak,et al.  Demonstration of an integrated capillary electrophoresis-laser-induced fluorescence fiber-optic sensor. , 1996, Talanta.

[16]  John M. Fini,et al.  Microstructure fibres for optical sensing in gases and liquids , 2004 .