Correction

The Careers feature 'Mind wide open' (Nature 525, 147–148; 2015) stated that BEST had offered career training to about 10,000 graduate students and 600 postdocs since its launch. In fact, at least 4,000 postdocs have benefited.

[1]  T. Shinkai,et al.  Metagenomic analysis of the rumen microbial community following inhibition of methane formation by a halogenated methane analog , 2015, Front. Microbiol..

[2]  P. Moate,et al.  An inhibitor persistently decreased enteric methane emission from dairy cows with no negative effect on milk production , 2015, Proceedings of the National Academy of Sciences.

[3]  N. Asanuma,et al.  Effects of nitrate addition to a diet on fermentation and microbial populations in the rumen of goats, with special reference to Selenomonas ruminantium having the ability to reduce nitrate and nitrite. , 2015, Animal science journal = Nihon chikusan Gakkaiho.

[4]  E. Okine,et al.  Sustained reduction in methane production from long-term addition of 3-nitrooxypropanol to a beef cattle diet. , 2015, Journal of animal science.

[5]  E. Ungerfeld.  Shifts in metabolic hydrogen sinks in the methanogenesis-inhibited ruminal fermentation: a meta-analysis , 2015, Front. Microbiol..

[6]  A. Bacher,et al.  Inhibition of methyl-CoM Reductase from Methanobrevibacter ruminantium by 2-bromoethanesulfonate. , 2014, Journal of agricultural and food chemistry.

[7]  J. McEwan,et al.  Genomic breed prediction in New Zealand sheep , 2014, BMC Genetics.

[8]  Yanning Zheng,et al.  Hydrogen Formation and Its Regulation in Ruminococcus albus: Involvement of an Electron-Bifurcating [FeFe]-Hydrogenase, of a Non-Electron-Bifurcating [FeFe]-Hydrogenase, and of a Putative Hydrogen-Sensing [FeFe]-Hydrogenase , 2014, Journal of bacteriology.

[9]  C. Reynolds,et al.  Effects of 3-nitrooxypropanol on methane emission, digestion, and energy and nitrogen balance of lactating dairy cows. , 2014, Journal of dairy science.

[10]  G. Martinez-Fernandez,et al.  Effects of ethyl-3-nitrooxy propionate and 3-nitrooxypropanol on ruminal fermentation, microbial abundance, and methane emissions in sheep. , 2014, Journal of dairy science.

[11]  S. Hay,et al.  Mapping the Global Distribution of Livestock , 2014, PloS one.

[12]  S. Suh,et al.  Elucidating the Process of Activation of Methyl-Coenzyme M Reductase , 2014, Journal of bacteriology.

[13]  P. Gerber,et al.  Special topics--Mitigation of methane and nitrous oxide emissions from animal operations: I. A review of enteric methane mitigation options. , 2013, Journal of animal science.

[14]  B. Jaun,et al.  Methyl-coenzyme M reductase from methanogenic archaea: isotope effects on the formation and anaerobic oxidation of methane. , 2013, Journal of the American Chemical Society.

[15]  Min Wang,et al.  A mathematical model to describe in vitro kinetics of H2 gas accumulation , 2013 .

[16]  P. Tocchetti,et al.  Metabolism and Pathways for Denitration of Organic Nitrates in the Human Liver , 2013, The Journal of Pharmacology and Experimental Therapeutics.

[17]  P. Janssen,et al.  Progress in the development of vaccines against rumen methanogens. , 2013, Animal : an international journal of animal bioscience.

[18]  S. Ragsdale,et al.  In vivo activation of methyl-coenzyme M reductase by carbon monoxide , 2013, Front. Microbiol..

[19]  W. Grajek,et al.  Physiological predisposition of various Clostridium species to synthetize 1,3-propanediol from glycerol , 2012 .

[20]  Kaarle Kupiainen,et al.  Simultaneously Mitigating Near-Term Climate Change and Improving Human Health and Food Security , 2012, Science.

[21]  C. Ghelardini,et al.  Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties. , 2011, Journal of medicinal chemistry.

[22]  C. Wilmot,et al.  Structural analysis of a Ni-methyl species in methyl-coenzyme M reductase from Methanothermobacter marburgensis. , 2011, Journal of the American Chemical Society.

[23]  Owen Johnson,et al.  iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM , 2011, Acta crystallographica. Section D, Biological crystallography.

[24]  Anne-Kristin Kaster,et al.  Coupling of ferredoxin and heterodisulfide reduction via electron bifurcation in hydrogenotrophic methanogenic archaea , 2011, Proceedings of the National Academy of Sciences.

[25]  E. Duin,et al.  Methyl-coenzyme M reductase from Methanothermobacter marburgensis. , 2011, Methods in enzymology.

[26]  P. Janssen.  Influence of hydrogen on rumen methane formation and fermentation balances through microbial growth kinetics and fermentation thermodynamics , 2010 .

[27]  C. Martin,et al.  Microbial ecosystem and methanogenesis in ruminants. , 2010, Animal : an international journal of animal bioscience.

[28]  Paul D. Adams,et al.  phenix.model_vs_data: a high-level tool for the calculation of crystallographic model and data statistics , 2010, Journal of applied crystallography.

[29]  R. Conrad,et al.  The global methane cycle: recent advances in understanding the microbial processes involved. , 2009, Environmental microbiology reports.

[30]  N. Scrutton,et al.  Reduction of aliphatic nitroesters and N‐nitramines by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase , 2008, The FEBS journal.

[31]  B. Jaun,et al.  Coordination and binding geometry of methyl-coenzyme M in the red1m state of methyl-coenzyme M reductase , 2008, JBIC Journal of Biological Inorganic Chemistry.

[32]  Anne-Kristin Kaster,et al.  Methanogenic archaea: ecologically relevant differences in energy conservation , 2008, Nature Reviews Microbiology.

[33]  Richard A. Friesner,et al.  Flexible ligand docking with Glide. , 2007, Current protocols in bioinformatics.

[34]  Matthew P. Repasky,et al.  Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes. , 2006, Journal of medicinal chemistry.

[35]  B. Jaun,et al.  A nickel-alkyl bond in an inactivated state of the enzyme catalyzing methane formation. , 2006, Angewandte Chemie.

[36]  U. Ermler.  On the mechanism of methyl-coenzyme M reductase. , 2005, Dalton transactions.

[37]  S. Frame,et al.  Inhalation Toxicity of 1,3-Propanediol in the Rat , 2005, Inhalation toxicology.

[38]  Thierry Langer,et al.  LigandScout: 3-D Pharmacophores Derived from Protein-Bound Ligands and Their Use as Virtual Screening Filters , 2005, J. Chem. Inf. Model..

[39]  Kevin Cowtan,et al.  research papers Acta Crystallographica Section D Biological , 2005 .

[40]  D. Boone,et al.  Effects of several inhibitors on pure cultures of ruminal methanogens * , 2004, Journal of applied microbiology.

[41]  B. Jaun,et al.  Probing the reactivity of Ni in the active site of methyl-coenzyme M reductase with substrate analogues , 2004, JBIC Journal of Biological Inorganic Chemistry.

[42]  B. Jaun,et al.  Spectroscopic investigation of the nickel-containing porphinoid cofactor F430. Comparison of the free cofactor in the +1, +2 and +3 oxidation states with the cofactor bound to methyl-coenzyme M reductase in the silent, red and ox forms , 2004, JBIC Journal of Biological Inorganic Chemistry.

[43]  Hege S. Beard,et al.  Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening. , 2004, Journal of medicinal chemistry.

[44]  Matthew P. Repasky,et al.  Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy. , 2004, Journal of medicinal chemistry.

[45]  R. Thauer,et al.  Growth parameters (Ks, μmax, Ys) of Methanobacterium thermoautotrophicum , 1980, Archives of Microbiology.

[46]  R. E. Hungate.  Hydrogen as an intermediate in the rumen fermentation , 2004, Archiv für Mikrobiologie.

[47]  R. Thauer.  Biochemistry of methanogenesis: a tribute to Marjory Stephenson. 1998 Marjory Stephenson Prize Lecture. , 1998, Microbiology.

[48]  A. Vagin,et al.  MOLREP: an Automated Program for Molecular Replacement , 1997 .

[49]  S. Shima,et al.  Crystal structure of methyl-coenzyme M reductase: the key enzyme of biological methane formation. , 1997, Science.

[50]  G. Murshudov,et al.  Refinement of macromolecular structures by the maximum-likelihood method. , 1997, Acta crystallographica. Section D, Biological crystallography.

[51]  M. P. Bryant,et al.  The rumen bacteria , 1997 .

[52]  D. Johnson,et al.  Methane emissions from cattle. , 1995, Journal of animal science.

[53]  R. Thauer,et al.  Properties of the two isoenzymes of methyl-coenzyme M reductase in Methanobacterium thermoautotrophicum. , 1993, European journal of biochemistry.

[54]  B. Lindenbach,et al.  Component A2 of methylcoenzyme M reductase system from Methanobacterium thermoautotrophicum delta H: nucleotide sequence and functional expression by Escherichia coli , 1993, Journal of bacteriology.

[55]  Stephen H. Zinder,et al.  Physiological Ecology of Methanogens , 1993 .

[56]  R. Thauer,et al.  Methyl-coenzyme-M reductase from Methanobacterium thermoautotrophicum (strain Marburg). Purity, activity and novel inhibitors. , 1989, European journal of biochemistry.

[57]  J. Konisky,et al.  Characterization of bromoethanesulfonate-resistant mutants of Methanococcus voltae: evidence of a coenzyme M transport system , 1987, Journal of bacteriology.

[58]  D. Lovley,et al.  Rapidly growing rumen methanogenic organism that synthesizes coenzyme M and has a high affinity for formate , 1984, Applied and environmental microbiology.

[59]  M. Wolin.  Fermentation in the rumen and human large intestine. , 1981, Science.

[60]  W. Balch,et al.  Transport of coenzyme M (2-mercaptoethanesulfonic acid) in Methanobacterium ruminantium , 1979, Journal of bacteriology.

[61]  R. Thauer,et al.  Energy conservation in chemotrophic anaerobic bacteria , 1977, Bacteriological reviews.

[62]  M. P. Bryant,et al.  Coenzyme M, Essential for Growth of a Rumen Strain of Methanobacterium ruminantium , 1974, Journal of bacteriology.