Modeling Circadian Oscillations with Interlocking Positive and Negative Feedback Loops
暂无分享,去创建一个
[1] B. Goodwin. Oscillatory behavior in enzymatic control processes. , 1965, Advances in enzyme regulation.
[2] Marcel Abendroth,et al. Biological delay systems: Linear stability theory , 1990 .
[3] M. Rosbash,et al. Circadian fluctuations of period protein immunoreactivity in the CNS and the visual system of Drosophila , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[4] M. Rosbash,et al. Temporal phosphorylation of the Drosophila period protein. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[5] L. Vosshall,et al. Block in nuclear localization of period protein by a second clock mutation, timeless. , 1994, Science.
[6] A. Sehgal,et al. Isolation of timeless by PER Protein Interaction: Defective Interaction Between timeless Protein and Long-Period Mutant PERL , 1995, Science.
[7] Jennifer J. Loros,et al. Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript , 1995, Cell.
[8] Michael W Young,et al. Regulation of Nuclear Entry of the Drosophila Clock Proteins Period and Timeless , 1996, Neuron.
[9] Zuwei Qian,et al. A light-entrainment mechanism for the Drosophila circadian clock , 1996, Nature.
[10] J. Lieb,et al. Sex-Specific Assembly of a Dosage Compensation Complex on the Nematode X Chromosome , 1996, Science.
[11] M. W. Young,et al. Light-Induced Degradation of TIMELESS and Entrainment of the Drosophila Circadian Clock , 1996, Science.
[12] Hongkui Zeng,et al. Effect of constant light and circadian entrainment of perS flies: evidence for light‐mediated delay of the negative feedback loop in Drosophila. , 1996, The EMBO journal.
[13] Yi Liu,et al. Alternative Initiation of Translation and Time-Specific Phosphorylation Yield Multiple Forms of the Essential Clock Protein FREQUENCY , 1997, Cell.
[14] J. Dunlap,et al. Neurospora wc-1 and wc-2: transcription, photoresponses, and the origins of circadian rhythmicity. , 1997, Science.
[15] M. Rosbash,et al. Post‐transcriptional regulation contributes to Drosophila clock gene mRNA cycling , 1997, The EMBO journal.
[16] M. Merrow,et al. Dissection of a circadian oscillation into discrete domains. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[17] I. Edery,et al. The Drosophila CLOCK Protein Undergoes Daily Rhythms in Abundance, Phosphorylation, and Interactions with the PER–TIM Complex , 1998, Neuron.
[18] Jeffrey C. Hall,et al. CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless , 1998, Cell.
[19] M. W. Young,et al. double-time Is a Novel Drosophila Clock Gene that Regulates PERIOD Protein Accumulation , 1998, Cell.
[20] D. Sidote,et al. Circadian Regulation of a Drosophila Homolog of the Mammalian Clock Gene: PER and TIM Function as Positive Regulators , 1998, Molecular and Cellular Biology.
[21] J. Dunlap,et al. Nuclear localization is required for function of the essential clock protein FRQ , 1998, The EMBO journal.
[22] A. Goldbeter,et al. A Model for Circadian Rhythms in Drosophila Incorporating the Formation of a Complex between the PER and TIM Proteins , 1998, Journal of biological rhythms.
[23] Michael W Young,et al. The Drosophila Clock Gene double-time Encodes a Protein Closely Related to Human Casein Kinase Iε , 1998, Cell.
[24] S. Kay,et al. Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim. , 1998, Science.
[25] Paul Smolen,et al. Effects of macromolecular transport and stochastic fluctuations on dynamics of genetic regulatory systems. , 1999, American journal of physiology. Cell physiology.
[26] P. Hardin,et al. Interlocked feedback loops within the Drosophila circadian oscillator. , 1999, Science.
[27] C. Pennartz,et al. A Mathematical Model for the Intracellular Circadian Rhythm Generator , 1999, The Journal of Neuroscience.
[28] J. Dunlap. Molecular Bases for Circadian Clocks , 1999, Cell.
[29] Steven M Reppert,et al. mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop , 1999, Cell.
[30] J. Tyson,et al. A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM. , 1999, Biophysical journal.
[31] A. Goldbeter,et al. Limit Cycle Models for Circadian Rhythms Based on Transcriptional Regulation in Drosophila and Neurospora , 1999, Journal of biological rhythms.
[32] I. Edery,et al. PER and TIM Inhibit the DNA Binding Activity of aDrosophila CLOCK-CYC/dBMAL1 Heterodimer without Disrupting Formation of the Heterodimer: a Basis for Circadian Transcription , 1999, Molecular and Cellular Biology.
[33] G. Macino,et al. Role of a white collar‐1–white collar‐2 complex in blue‐light signal transduction , 1999, The EMBO journal.
[34] P Ruoff,et al. The Goodwin model: simulating the effect of cycloheximide and heat shock on the sporulation rhythm of Neurospora crassa. , 1999, Journal of theoretical biology.
[35] P. Lakin-Thomas,et al. Circadian rhythms in Neurospora crassa: lipid deficiencies restore robust rhythmicity to null frequency and white-collar mutants. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[36] J. C. Hall,et al. Differential regulation of circadian pacemaker output by separate clock genes in Drosophila. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[37] Martin A. Lema,et al. Delay model of the circadian pacemaker. , 2000, Journal of theoretical biology.
[38] A. Goldbeter,et al. Modeling the molecular regulatory mechanism of circadian rhythms in Drosophila. , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.
[39] M. Hastings,et al. Circadian clockwork: two loops are better than one , 2000, Nature Reviews Neuroscience.
[40] D Gonze,et al. Theoretical models for circadian rhythms in Neurospora and Drosophila. , 2000, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.
[41] J. Dunlap,et al. Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[42] K Kume,et al. Interacting molecular loops in the mammalian circadian clock. , 2000, Science.
[43] H. Iwasaki,et al. Microbial circadian oscillatory systems in Neurospora and Synechococcus: models for cellular clocks. , 2000, Current opinion in microbiology.
[44] P. Lakin-Thomas. Circadian rhythms: new functions for old clock genes. , 2000, Trends in genetics : TIG.
[45] J. Dunlap,et al. Interconnected feedback loops in the Neurospora circadian system. , 2000, Science.
[46] D. A. Baxter,et al. Modeling transcriptional control in gene networks—methods, recent results, and future directions , 2000, Bulletin of mathematical biology.
[47] Paul E. Hardin,et al. dCLOCK Is Present in Limiting Amounts and Likely Mediates Daily Interactions between the dCLOCK–CYC Transcription Factor and the PER–TIM Complex , 2000, The Journal of Neuroscience.
[48] D. A. Baxter,et al. Mathematical Modeling of Gene Networks , 2000, Neuron.
[49] J. Dunlap,et al. WC‐2 mediates WC‐1–FRQ interaction within the PAS protein‐linked circadian feedback loop of Neurospora , 2001, The EMBO journal.