A cross‐sectional investigation of cognition and epileptiform discharges in juvenile absence epilepsy

Despite the prevalence of cognitive symptoms in the idiopathic generalized epilepsies (IGEs), cognitive dysfunction in juvenile absence epilepsy (JAE), a common yet understudied IGE subtype, remains poorly understood. This descriptive study provides a novel, comprehensive characterization of cognitive functioning in a JAE sample and examines the relationship between cognition and 24‐h epileptiform discharge load.

[1]  U. Seneviratne,et al.  Brainwaves beyond diagnosis: Wider applications of electroencephalography in idiopathic generalized epilepsy , 2021, Epilepsia.

[2]  E. Hessen,et al.  Addressing neuropsychological diagnostics in adults with epilepsy: Introducing the International Classification of Cognitive Disorders in Epilepsy: The IC CODE Initiative , 2021, Epilepsia open.

[3]  I. Karakis,et al.  Concurrent EEG monitoring helps interpret neuropsychological testing results in patients with epilepsy , 2020, Epilepsy & Behavior.

[4]  M. Koepp,et al.  Cognitive Function in Genetic Generalized Epilepsies: Insights From Neuropsychology and Neuroimaging , 2020, Frontiers in Neurology.

[5]  M. Cook,et al.  “Sleep Surge”: The impact of sleep onset and offset on epileptiform discharges in idiopathic generalized epilepsies , 2020, Clinical Neurophysiology.

[6]  J. Murre,et al.  The Factor Structure of Cognitive Functioning in Cognitively Healthy Participants: a Meta-Analysis and Meta-Analysis of Individual Participant Data , 2020, Neuropsychology Review.

[7]  U. Seneviratne,et al.  The effect of antiepileptic drugs on epileptiform discharges in genetic generalized epilepsy: A systematic review , 2019, Epilepsy & Behavior.

[8]  I. García-Morales,et al.  The cognitive phenotype of idiopathic generalized epilepsy , 2018, Epilepsy & Behavior.

[9]  Christian E Elger,et al.  Diagnostic challenges in epilepsy: seizure under-reporting and seizure detection , 2018, The Lancet Neurology.

[10]  Adriana Bermeo-Ovalle,et al.  Cognitive Problems in Epilepsy: Are Interictal Epileptiform Discharges to Blame? , 2018, Epilepsy currents.

[11]  Mark J. Cook,et al.  Electroencephalography in the Diagnosis of Genetic Generalized Epilepsy Syndromes , 2017, Front. Neurol..

[12]  Paul A. Jewsbury,et al.  Construct Validity of Fluency and Implications for the Factorial Structure of Memory , 2017 .

[13]  Edouard Hirsch,et al.  ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology , 2017, Epilepsia.

[14]  Wendyl D'Souza,et al.  EEG correlates of seizure freedom in genetic generalized epilepsies , 2017, Neurology. Clinical practice.

[15]  S. Baxendale,et al.  Reprint of: The new approach to epilepsy classification: Cognition and behavior in adult epilepsy syndromes , 2016, Epilepsy & Behavior.

[16]  M. Cook,et al.  Temporal patterns of epileptiform discharges in genetic generalized epilepsies , 2016, Epilepsy & Behavior.

[17]  W. D’Souza,et al.  A Systematic Review of Psychiatric and Psychosocial Comorbidities of Genetic Generalised Epilepsies (GGE) , 2016, Neuropsychology Review.

[18]  Udaya Seneviratne,et al.  Epilepsy beyond seizures: Predicting enduring cognitive dysfunction in genetic generalized epilepsies , 2016, Epilepsy & Behavior.

[19]  Mark S. Seidenberg,et al.  Cognitive phenotypes in childhood idiopathic epilepsies , 2016, Epilepsy & Behavior.

[20]  M. Cook,et al.  Consistent topography and amplitude symmetry are more typical than morphology of epileptiform discharges in genetic generalized epilepsy , 2016, Clinical Neurophysiology.

[21]  Paul A. Jewsbury,et al.  Integrating the switching, inhibition, and updating model of executive function with the Cattell-Horn-Carroll model. , 2016, Journal of experimental psychology. General.

[22]  G. Ghacibeh,et al.  Epilepsy and Cognition , 2016 .

[23]  R. Tuchman,et al.  The other side of epilepsy , 2015, Epilepsia.

[24]  K. Nickels Seizure and Psychosocial Outcomes of Childhood and Juvenile Onset Generalized Epilepsies: Wolf in Sheep's Clothing, or Well-Dressed Wolf? , 2015, Epilepsy currents.

[25]  W. D’Souza,et al.  Cognitive functioning in idiopathic generalised epilepsies: A systematic review and meta-analysis , 2014, Neuroscience & Biobehavioral Reviews.

[26]  Li Cui,et al.  Cognitive correlates of interictal epileptiform discharges in adult patients with epilepsy in China , 2013, Epilepsy & Behavior.

[27]  E. Mizrahi,et al.  Pretreatment EEG in childhood absence epilepsy , 2013, Neurology.

[28]  J. Born,et al.  About sleep's role in memory. , 2013, Physiological reviews.

[29]  M. Cook,et al.  The prognosis of idiopathic generalized epilepsy , 2012, Epilepsia.

[30]  C. Helmstaedter,et al.  The effects of levetiracetam on cognition: A non-interventional surveillance study , 2008, Epilepsy & Behavior.

[31]  M. Tenhunen,et al.  Beneficial effects of antiepileptic medication on absence seizures and cognitive functioning in children , 2007, Epilepsy & Behavior.

[32]  S. Chokroverty,et al.  The visual scoring of sleep in adults. , 2007, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[33]  A. Aldenkamp,et al.  Psychopathology in children with epilepsy: a meta-analysis. , 2005, Journal of pediatric psychology.

[34]  K. McGrew The Cattell-Horn-Carroll Theory of Cognitive Abilities: Past, Present, and Future. , 2005 .

[35]  J. Arends,et al.  The Relative Influence of Epileptic EEG Discharges, Short Nonconvulsive Seizures, and Type of Epilepsy on Cognitive Function , 2004, Epilepsia.

[36]  C. Binnie,et al.  Cognitive impairment during epileptiform discharges: is it ever justifiable to treat the EEG? , 2003, The Lancet Neurology.

[37]  L. Ford,et al.  Assessment with the Woodcock-Johnson III and Young Children , 2003 .

[38]  Henry L. Janzen,et al.  Handbook of psychoeducational assessment : ability, achievement, and behavior in children , 2001 .

[39]  G. Kostopoulos,et al.  Spike-and-wave discharges of absence seizures as a transformation of sleep spindles: the continuing development of a hypothesis , 2000, Clinical Neurophysiology.

[40]  R. Gunst Applied Regression Analysis , 1999, Technometrics.

[41]  E. Wirrell,et al.  Long-term psychosocial outcome in typical absence epilepsy. Sometimes a wolf in sheeps' clothing. , 1997, Archives of pediatrics & adolescent medicine.

[42]  O. Spreen,et al.  A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary , 1991 .

[43]  K J Rothman,et al.  No Adjustments Are Needed for Multiple Comparisons , 1990, Epidemiology.