Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease.

[1]  P. Boor,et al.  Interleukin-1α Is a Central Regulator of Leukocyte-Endothelial Adhesion in Myocardial Infarction and in Chronic Kidney Disease , 2021, Circulation.

[2]  M. Nyegaard,et al.  Sortilin as a Biomarker for Cardiovascular Disease Revisited , 2021, Frontiers in Cardiovascular Medicine.

[3]  J. Lash,et al.  Protein carbamylation and chronic kidney disease progression in the Chronic Renal Insufficiency Cohort Study. , 2020, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[4]  F. Lang,et al.  Circulating uromodulin inhibits vascular calcification by interfering with pro-inflammatory cytokine signaling. , 2020, Cardiovascular research.

[5]  S. Achenbach,et al.  Epicardial fat, cardiovascular risk factors and calcifications in patients with chronic kidney disease , 2019, Clinical kidney journal.

[6]  K. Mucha,et al.  IL 6 but not TNF is linked to coronary artery calcification in patients with chronic kidney disease. , 2019, Cytokine.

[7]  M. González-Gay,et al.  IL-6: linking chronic inflammation and vascular calcification , 2019, Nature Reviews Rheumatology.

[8]  M. Rudnicki,et al.  Dickkopf-3 (DKK3) in Urine Identifies Patients with Short-Term Risk of eGFR Loss. , 2018, Journal of the American Society of Nephrology : JASN.

[9]  B. Janssen,et al.  Structural insights into SorCS2–Nerve Growth Factor complex formation , 2018, Nature Communications.

[10]  S. Takashima,et al.  Protein carbamylation exacerbates vascular calcification. , 2018, Kidney international.

[11]  Z. Massy,et al.  New insights into the key role of interleukin 6 in vascular calcification of chronic kidney disease. , 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[12]  P. Boor,et al.  The new SFB/TRR219 Research Centre. , 2018, European heart journal.

[13]  R. Maki,et al.  Myeloperoxidase-catalyzed oxidation of cyanide to cyanate: A potential carbamylation route involved in the formation of atherosclerotic plaques? , 2018, The Journal of Biological Chemistry.

[14]  E. Aikawa,et al.  Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases. , 2018, Arteriosclerosis, thrombosis, and vascular biology.

[15]  S. Thirup,et al.  Acidic Environment Induces Dimerization and Ligand Binding Site Collapse in the Vps10p Domain of Sortilin. , 2017, Structure.

[16]  S. Stirdivant,et al.  Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension , 2017, PloS one.

[17]  A. von Eckardstein,et al.  Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease , 2017, European heart journal.

[18]  Joshua D. Hutcheson,et al.  Serum Sortilin Associates With Aortic Calcification and Cardiovascular Risk in Men , 2017, Arteriosclerosis, thrombosis, and vascular biology.

[19]  A. Hirayama,et al.  Soluble sortilin is released by activated platelets and its circulating levels are associated with cardiovascular risk factors. , 2016, Atherosclerosis.

[20]  H. Bøtker,et al.  Danish study of Non-Invasive testing in Coronary Artery Disease (Dan-NICAD): study protocol for a randomised controlled trial , 2016, Trials.

[21]  P. Libby,et al.  Sortilin mediates vascular calcification via its recruitment into extracellular vesicles. , 2016, The Journal of clinical investigation.

[22]  M. Köhler,et al.  Protein carbamylation is a hallmark of aging , 2015, Proceedings of the National Academy of Sciences.

[23]  D. Fliser,et al.  Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease. , 2015, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[24]  M. Tonelli,et al.  Cause of Death in Patients with Reduced Kidney Function. , 2015, Journal of the American Society of Nephrology : JASN.

[25]  M. Nielsen,et al.  Sortilin, Encoded by the Cardiovascular Risk Gene SORT1, and Its Suggested Functions in Cardiovascular Disease , 2015, Current Atherosclerosis Reports.

[26]  C. Wanner,et al.  Protein carbamylation is associated with heart failure and mortality in diabetic patients with end stage renal disease , 2015, Kidney international.

[27]  E. Falk,et al.  Targeting sortilin in immune cells reduces proinflammatory cytokines and atherosclerosis. , 2014, The Journal of clinical investigation.

[28]  A. Akhmedov,et al.  Carbamylated low-density lipoprotein induces endothelial dysfunction. , 2014, European heart journal.

[29]  Cornelia M. Wilson,et al.  Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors , 2014, Journal of Cell Science.

[30]  Chi Pang Wen,et al.  Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention , 2013, The Lancet.

[31]  R. Herwig,et al.  The enzymatic activity of the VEGFR2 receptor for the biosynthesis of dinucleoside polyphosphates , 2013, Journal of Molecular Medicine.

[32]  Hans-Ulrich Prokosch,et al.  The German Chronic Kidney Disease (GCKD) study: design and methods. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[33]  C. Blobel,et al.  Neuronal Brain-derived Neurotrophic Factor Is Synthesized in Excess, with Levels Regulated by Sortilin-mediated Trafficking and Lysosomal Degradation , 2011, The Journal of Biological Chemistry.

[34]  H. Feldman,et al.  Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin , 2010, Neuron.

[35]  Sudhir V. Shah,et al.  Chronic uremia stimulates LDL carbamylation and atherosclerosis. , 2010, Journal of the American Society of Nephrology : JASN.

[36]  S. Sirpal Myeloperoxidase-mediated lipoprotein carbamylation as a mechanistic pathway for atherosclerotic vascular disease. , 2009, Clinical science.

[37]  P. McCullough,et al.  Accelerated atherosclerotic calcification and Monckeberg's sclerosis: a continuum of advanced vascular pathology in chronic kidney disease. , 2008, Clinical journal of the American Society of Nephrology : CJASN.

[38]  S. Ricard-Blum,et al.  Impact of carbamylation on type I collagen conformational structure and its ability to activate human polymorphonuclear neutrophils. , 2006, Chemistry & biology.

[39]  J. Vincent,et al.  Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line. , 2002, Biochemical and biophysical research communications.

[40]  S. Moestrup,et al.  Propeptide cleavage conditions sortilin/neurotensin receptor‐3 for ligand binding , 1999, The EMBO journal.

[41]  J. Kimmel [70] Guanidination of proteins , 1967 .