Use of Wideband Acoustic Immittance in Neonates and Infants

Abstract With widespread agreement on the importance of early identification of hearing loss, universal newborn hearing screening (UNHS) has become the standard of care in several countries. Despite advancements in screening technology, UNHS and early hearing detection and intervention programs continue to be burdened by high referral rates of false-positive cases due to temporary obstruction of sound in the outer/middle ear at birth. A sensitive adjunct test of middle ear at the time of screening would aid in the interpretation of screening outcomes, minimize unnecessary rescreens, and prioritize referral to diagnostic assessment for infants with permanent congenital hearing loss. Determination of middle ear status is also an important aspect of diagnostic assessment in infants. Standard single-frequency tympanometry used to determine middle ear status in infants is neither efficient nor accurate in newborns and young infants. A growing body of research has demonstrated the utility of wideband acoustic immittance (WAI) testing in both screening and diagnostic settings. Wideband power absorbance (WBA), a WAI measure, has been shown to be more sensitive than tympanometry in the assessment of outer/middle ear function in newborns. Furthermore, age-graded norms also support successful application of WBA in young infants. Despite its merits, uptake of this technology is low among pediatric audiologists and hearing screening health workers. This report describes normative data, methods for assessment and interpretation of WBA, test–retest variations, and other factors pertinent to clinical use of WAI in newborns and infants. Clinical cases illustrate the use of WAI testing in newborn and infant hearing assessment.

[1]  B. Prieve,et al.  Refining Measurements of Power Absorbance in Newborns: Probe Fit and Intrasubject Variability , 2020, Ear and hearing.

[2]  J. Kei,et al.  Pressurized Wideband Absorbance Findings in Healthy Neonates: A Preliminary Study. , 2017, Journal of speech, language, and hearing research : JSLHR.

[3]  J. Kei,et al.  Normative Study of Wideband Acoustic Immittance Measures in Newborn Infants. , 2017, Journal of speech, language, and hearing research : JSLHR.

[4]  J. Kei,et al.  Effect of ear canal pressure and age on wideband absorbance in young infants , 2017, International journal of audiology.

[5]  Denis F. Fitzpatrick,et al.  Longitudinal development of wideband reflectance tympanometry in normal and at-risk infants , 2016, Hearing Research.

[6]  S. E. Voss,et al.  Reflectance Measures from Infant Ears With Normal Hearing and Transient Conductive Hearing Loss , 2016, Ear and hearing.

[7]  Denis F. Fitzpatrick,et al.  Procedures for ambient-pressure and tympanometric tests of aural acoustic reflectance and admittance in human infants and adults. , 2015, The Journal of the Acoustical Society of America.

[8]  J. Kei,et al.  Wideband Absorbance Outcomes in Newborns: A Comparison With High-Frequency Tympanometry, Automated Brainstem Response, and Transient Evoked and Distortion Product Otoacoustic Emissions , 2015, Ear and hearing.

[9]  J. Rosowski,et al.  Acoustic Immittance, Absorbance, and Reflectance in the Human Ear Canal , 2015, Seminars in Hearing.

[10]  Suhana Alam,et al.  Early hearing detection and intervention among infants--hearing screening and follow-up survey, United States, 2005-2006 and 2009-2010. , 2014, MMWR supplements.

[11]  Navid Shahnaz,et al.  Understanding the developmental course of the acoustic properties of the human outer and middle ear over the first 6 months of life by using a longitudinal analysis of power reflectance at ambient pressure. , 2014, Journal of the American Academy of Audiology.

[12]  J. Kei,et al.  Wideband absorbance in young infants (0-6 months): a cross-sectional study. , 2014, Journal of the American Academy of Audiology.

[13]  H. Wada,et al.  Normative sweep frequency impedance measures in healthy neonates. , 2014, Journal of the American Academy of Audiology.

[14]  J. Kei,et al.  Wideband Acoustic Immittance Measures: Developmental Characteristics (0 to 12 Months) , 2013, Ear and hearing.

[15]  Susan E Voss,et al.  Factors That Introduce Intrasubject Variability Into Ear-Canal Absorbance Measurements , 2013, Ear and hearing.

[16]  K. Schairer,et al.  Wideband Acoustic Immittance Normative Data: Ethnicity, Gender, Aging, and Instrumentation , 2013, Ear and hearing.

[17]  L. Hunter,et al.  Wideband Acoustic Immittance: Tympanometric Measures , 2013, Ear and hearing.

[18]  J. Preston,et al.  Identification of Conductive Hearing Loss in Young Infants Using Tympanometry and Wideband Reflectance , 2013, Ear and hearing.

[19]  Denis F. Fitzpatrick,et al.  Wideband aural acoustic absorbance predicts conductive hearing loss in children , 2012, International journal of audiology.

[20]  J. Kei,et al.  Conductive hearing loss and middle ear pathology in young infants referred through a newborn universal hearing screening program in Australia. , 2012, Journal of the American Academy of Audiology.

[21]  Denis F. Fitzpatrick,et al.  Wideband acoustic transfer functions predict middle‐ear effusion , 2012, The Laryngoscope.

[22]  S. E. Voss,et al.  Normative Reflectance and Transmittance Measurements on Healthy Newborn and 1-Month-Old Infants , 2010, Ear and hearing.

[23]  L. Hunter,et al.  Wideband Reflectance in Newborns: Normative Regions and Relationship to Hearing-Screening Results , 2010, Ear and hearing.

[24]  L. Werner,et al.  Ear-Canal Wideband Acoustic Transfer Functions of Adults and Two- to Nine-Month-Old Infants , 2010, Ear and hearing.

[25]  B. Westerberg,et al.  Wideband Reflectance in Normal Caucasian and Chinese School-Aged Children and in Children with Otitis Media with Effusion , 2010, Ear and hearing.

[26]  Denis F. Fitzpatrick,et al.  Sound-Conduction Effects on Distortion-Product Otoacoustic Emission Screening Outcomes in Newborn Infants: Test Performance of Wideband Acoustic Transfer Functions and 1-kHz Tympanometry , 2009, Ear and hearing.

[27]  N. Longridge,et al.  Energy Reflectance and Tympanometry in Normal and Otosclerotic Ears , 2009, Ear and hearing.

[28]  Chris A. Sanford,et al.  Effects of maturation on tympanometric wideband acoustic transfer functions in human infants. , 2008, The Journal of the Acoustical Society of America.

[29]  Lisa L Hunter,et al.  Wideband middle ear power measurement in infants and children. , 2008, Journal of the American Academy of Audiology.

[30]  J. Kei,et al.  Measuring middle ear admittance in newborns using 1000 Hz tympanometry: a comparison of methodologies. , 2007, Journal of the American Academy of Audiology.

[31]  Jackson Roush,et al.  Year 2007 Position Statement: Principles and Guidelines for Early Hearing Detection and Intervention Programs , 2007, Pediatrics.

[32]  Kathy R Vander Werff,et al.  Test-Retest Reliability of Wideband Reflectance Measures in Infants under Screening and Diagnostic Test Conditions , 2007, Ear and hearing.

[33]  Jan Wouters,et al.  Evaluation of Middle Ear Function in Young Children: Clinical Guidelines for the Use of 226- and 1,000-Hz Tympanometry , 2007, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

[34]  B. Louw,et al.  High frequency immittance for neonates: a normative study , 2007, Acta oto-laryngologica.

[35]  Justyn Lutfy,et al.  A nonlinear finite-element model of the newborn ear canal. , 2006, The Journal of the Acoustical Society of America.

[36]  M. Baldwin Choice of probe tone and classification of trace patterns in tympanometry undertaken in early infancy , 2006, International journal of audiology.

[37]  B. Vohr,et al.  A Multicenter Evaluation of How Many Infants With Permanent Hearing Loss Pass a Two-Stage Otoacoustic Emissions/Automated Auditory Brainstem Response Newborn Hearing Screening Protocol , 2005, Pediatrics.

[38]  D. H. Keefe,et al.  Energy transmittance predicts conductive hearing loss in older children and adults. , 2003, The Journal of the Acoustical Society of America.

[39]  R. Margolis,et al.  Tympanometry in newborn infants--1 kHz norms. , 2003, Journal of the American Academy of Audiology.

[40]  Stephen T Neely,et al.  Ear-canal acoustic admittance and reflectance measurements in human neonates. II. Predictions of middle-ear in dysfunction and sensorineural hearing loss. , 2003, The Journal of the Acoustical Society of America.

[41]  M. Helfand,et al.  Universal newborn hearing screening: summary of evidence. , 2001, JAMA.

[42]  C. Yoshinaga-Itano,et al.  The Colorado Newborn Hearing Screening Project: Effects on Speech and Language Development for Children With Hearing Loss , 2000, Journal of Perinatology.

[43]  J. Hearing Year 2007 position statement: Principles and guidelines for early hearing detection and intervention programs. , 2000, Pediatrics.

[44]  Welfare Agencies,et al.  Year 2000 Position Statement: Principles and Guidelines for Early Hearing Detection and Intervention Programs , 2000, Pediatrics.

[45]  B. Vohr,et al.  Identification of Neonatal Hearing Impairment: Ear-Canal Measurements of Acoustic Admittance and Reflectance in Neonates , 2000, Ear and hearing.

[46]  K. Doyle,et al.  External and middle ear effects on infant hearing screening test results , 2000, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[47]  A. Cacace,et al.  New York State Universal Newborn Hearing Screening Demonstration Project: Inpatient Outcome Measures , 2000, Ear and hearing.

[48]  Akihiko Ikui, Isamu Sando, Shin-Ichi Haginomori, M Postnatal Development of the Tympanic Cavity: a Computer-aided Reconstruction and Measurement Study , 2000 .

[49]  C. Kennedy Controlled trial of universal neonatal screening for early identification of permanent childhood hearing impairment: coverage, positive predictive value, effect on mothers and incremental yield , 1999, Acta paediatrica (Oslo, Norway : 1992). Supplement.

[50]  D H Keefe,et al.  Wideband reflectance tympanometry in normal adults. , 1999, The Journal of the Acoustical Society of America.

[51]  J. Hirsch,et al.  Hearing Screening in the Newborn Intensive Care Nursery: Comparison of Methods , 1999, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[52]  Christine Yoshinaga-Itano,et al.  Language of Early- and Later-identified Children With Hearing Loss , 1998, Pediatrics.

[53]  C. Jardine,et al.  Developmental changes in tympanometry: a case study. , 1997, British journal of audiology.

[54]  I. Sando,et al.  Postnatal Change in Angle between the Tympanic Annulus and Surrounding Structures , 1997, The Annals of otology, rhinology, and laryngology.

[55]  D. H. Keefe,et al.  Maturation of the Middle and External Ears: Acoustic Power‐Based Responses and Reflectance Tympanometry , 1996, Ear and hearing.

[56]  A. Stuart,et al.  Neonatal auditory brainstem response thresholds to air- and bone-conducted clicks: 0 to 96 hours postpartum. , 1994, Journal of the American Academy of Audiology.

[57]  D H Keefe,et al.  Ear-canal impedance and reflection coefficient in human infants and adults. , 1993, The Journal of the Acoustical Society of America.

[58]  B. Vohr,et al.  External and middle ear status related to evoked otoacoustic emission in neonates. , 1993, Archives of otolaryngology--head & neck surgery.

[59]  D. Zelterman,et al.  Age-related morphologic changes in the human tympanic membrane. A light and electron microscopic study. , 1991, Archives of otolaryngology--head & neck surgery.

[60]  S. Friel-Patti,et al.  Language learning in a prospective study of otitis media with effusion in the first two years of life. , 1990, Journal of speech and hearing research.

[61]  R. M. Cavanaugh Pneumatic otoscopy in healthy full-term infants. , 1987, Pediatrics.

[62]  C. Marchant,et al.  Objective diagnosis of otitis media in early infancy by tympanometry and ipsilateral acoustic reflex thresholds. , 1986, The Journal of pediatrics.

[63]  J. Paradise Pediatrician's View of Middle Ear Effusions: More Questions than Answers , 1976, The Annals of otology, rhinology, and laryngology.

[64]  R. A. Johnson,et al.  EMBRYONAL CONNECTIVE TISSUE AND EXUDATE IN EAR. A HISTOLOGICAL STUDY OF EAR SECTIONS OF FETUSES AND INFANTS. , 1964, American journal of diseases of children.

[65]  Hammam AlMakadma,et al.  REFINING THE CLINICAL MEASUREMENT OF WIDEBAND ACOUSTIC IMMITTANCE IN NEWBORNS , 2017 .

[66]  J. Kei,et al.  High-frequency (1000 Hz) tympanometry in normal neonates. , 2003, Journal of the American Academy of Audiology.

[67]  L S Chan,et al.  Diagnosis, natural history, and late effects of otitis media with effusion. , 2002, Evidence report/technology assessment.

[68]  I. Sando,et al.  Postnatal development of the tympanic cavity: a computer-aided reconstruction and measurement study. , 2000, Acta oto-laryngologica.

[69]  S. Purdy,et al.  High frequency probe tone tympanometry in infants with middle ear effusion , 1995 .

[70]  R. Margolis,et al.  Developmental changes in multifrequency tympanograms. , 1991, Audiology : official organ of the International Society of Audiology.

[71]  V. J. Vanhuyse,et al.  On the W-Notching of Tympanograms , 1975 .